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B lymphocytes and tertiary lymphoid structures have a prognostic impact on penile squamous cell carcinoma. [PDF]
Zavillová N +8 more
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A dual diacylglycerol kinase (DGK) alpha/zeta inhibitor augments the activity of human tumor infiltrating lymphocytes in <i>in vivo</i> and <i>ex vivo</i> models. [PDF]
Areesawangkit P +20 more
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CSDE1 depletion inhibits tumor progression through enhancing B-cell infiltration in NSCLC. [PDF]
Li W +12 more
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Editorial: Unveiling the next generation of cancer immunity & immunotherapy. [PDF]
Sadasivam M, Muniraj N, Thangavel C.
europepmc +1 more source
FAM135B Deficiency Inhibits Cytotoxic T-cell Activity in Triple-Negative Breast Cancer by Blocking the IFI16-Dependent STING Pathway. [PDF]
Lin W +7 more
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Tumor-Infiltrating Lymphocytes
The Cancer Journal, 2015Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TILs) in combination with lymphodepletion and high-dose interleukin 2 has shown reproducible objective response rates of approximately 50% in patients with highly advanced, refractory metastatic melanoma.
Michal J, Besser +2 more
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Clonal dynamics of tumor-infiltrating lymphocytes
European Journal of Immunology, 2005The presence of tumor-infiltrating lymphocytes (TIL) provides important evidence of anti-tumor immunity in vivo. However, TIL are usually not sufficient for inhibiting tumor growth. We explored the spatial and temporal aspects of clonal accumulation of TIL using RT-PCR/single-strand conformation polymorphism analysis.
Rong, Yu +4 more
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Tumor-Infiltrating Lymphocyte Therapy
The Cancer Journal, 2015Autologous adoptive T-cell therapies have made tremendous strides over the last few years with excitement currently being generated by technologies that can reprogram T-cell specificities toward any desired antigen including chimeric antigen receptors and recombinant T-cell receptors.
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