Results 71 to 80 of about 23,252 (297)

Microscopic colitis: Etiopathology, diagnosis, and rational management

eLife, 2022
Microscopic colitis is an inflammatory bowel disease divided into two subtypes: collagenous colitis and lymphocytic colitis. With an increasing incidence of microscopic colitis exceeding those of ulcerative and Crohn’s disease among elderly people in ...
Ole Haagen Nielsen, Fernando Fernandez-Banares, Toshiro Sato, Darrell S Pardi   +3 more
doaj   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

Oral chondroitin sulfate and prebiotics for the treatment of canine Inflammatory Bowel Disease: a randomized, controlled clinical trial [PDF]

, 2016
BACKGROUND Canine inflammatory bowel disease (IBD) is a chronic enteropathy of unknown etiology, although microbiome dysbiosis, genetic susceptibility, and dietary and/or environmental factors are hypothesized to be involved in its pathogenesis. Since
A Ghiselli, A Tvarijonaviciute, A Wächtershäuser, ABC Samuelsen, AE Jergens, AE Jergens, AJ Schottelius, Alberto Muñoz-Prieto, Alfonso Velasco, Antonio Rodríguez-Bertos, CG Fraga, CS Brennan, D Boehm, D Martínez-Puig, Daniel Martínez-Puig, E Gisbert, Fernando Rodríguez-Franco, G Rossi, G Rossi, IE Koutroubakis, JE Fogle, JJ Ceron, José Cerón, JS Suchodolski, JS Suchodolski, K Allenspach, K Allenspach, Karin Allenspach, KS Swanson, KW Simpson, L Kaufman, M Castillo, M García-Sancho, M Krzystek-Korpacka, M Nofrarías, M Roca, M Volkmann, MA Murphy, Marta Cerdà-Cuéllar, MT Collins, N Luckschander, O Erel, P Souich du, PG Xenoulis, RJ Washabau, S Martinez-Subiela, Sergi Segarra, Silvia Martínez-Subiela, TM McCann, VL Cabral, Y Minamoto, Y You   +51 more
core   +6 more sources

Lymphocytic colitis: a distinct clinical entity? A clinicopathological confrontation of lymphocytic and collagenous colitis [PDF]

Gut, 1999
BACKGROUND AND AIMS It is not known whether lymphocytic colitis and collagenous colitis represent different clinical entities or constitute part of a spectrum of disease. METHODS Detailed clinical features and histological findings ...
Baert, F., Wouters, K., D'Haens, G., Hoang, P., Naegels, S., D'Heygere, F., Holvoet, J., Louis, Edouard, Devos, Martine, Geboes, K.   +9 more
openaire   +5 more sources

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

The price of tumor control [PDF]

, 2013
Ipilimumab, a cytotoxic T-lymphocyte antigen-4 (CTLA-4) blocking antibody, has been approved for the treatment of metastatic melanoma and induces adverse events (AE) in up to 64% of patients.
Bergmann, Tanja, Berking, Carola, Bockmeyer, Clemens L., Dummer, Reinhard, Eigentler, Thomas, Fluck, Michael, Garbe, Claus, Goldinger, Simone M., Grabbe, Stephan, Gutzmer, Ralf, Göppner, Daniela, Hauschild, Axel, Hein, Rüdiger, Heinzerling, Lucie M., Hundorfean, Gheorghe, Justich, Armin, Kaehler, Katharina C., Keller, Ullrich, Klein, Christina, Loquai, Carmen, Mateus, Christine, Mohr, Peter, Moos, Roger von, Paetzold, Sylvie, Robert, Caroline, Satzger, Imke, Schadendorf, Dirk, Schlaeppi, Marc, Schuler, Gerold, Schuler-Thurner, Beatrice, Trefzer, Uwe, Ulrich, Jens, Vaubel, Julia, Voskens, Caroline J., Weder, Patrik, Wilhelm, Tabea   +35 more
core   +1 more source

T cells, the next big target in axSpA?

Arthritis &Rheumatology, Accepted Article.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells.
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

The occurrence of diversion colitis in patients with a sigmoid neovagina [PDF]

, 1993
Diversion colitis is an inflammatory process occurring in segments of the colorectum surgically diverted from the fecal stream. Clinical symptoms of this condition are rectal discomfort, pain, discharge, and bleeding.
Chadha-Ajwani, S. (Savi), Drogendijk, A.C., Freundt, I. (Ingrid), Huikeshoven, F.J. (Frans), Jeekel, J. (Hans), Toolenaar, T.A.   +5 more
core   +2 more sources

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

British Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse, Christophe Hommel, Nadine Petitpain, Philippe Kerschen   +3 more
wiley   +1 more source

Identification of a new intestinal spirochete with pathogenicity for chickens [PDF]

, 1995
Two intestinal spirochete isolates obtained from chickens with diarrhea were examined by electron microscopy, biochemical tests, rRNA gene restriction pattern analysis, and multilocus enzyme electrophoresis.
Swayne, D.E, Eaton, K.A., Stoutenburg, J., Trott, D.J., Hampson, D.J., Jensen, N.S.   +5 more
core   +1 more source