Results 91 to 100 of about 22,112 (212)

Screening assays for primary haemophagocytic lymphohistiocytosis in children presenting with suspected macrophage activation syndrome [PDF]

, 2014
BACKGROUND: Primary haemophagocytic lymphohistiocytosis (HLH) screening assays are increasingly being performed in patients presenting with macrophage activation syndrome (MAS).
Anoop, P, Brogan, PA, Cruikshank, M, Eleftheriou, D, Gilmour, K, Nikolajeva, O, Rao, A, Rao, K   +7 more
core  

X-Linked Lymphoproliferative Disease Type 1: A Clinical and Molecular Perspective [PDF]

, 2018
X-linked lymphoproliferative disease (XLP) was first described in the 1970s as a fatal lymphoproliferative syndrome associated with infection with Epstein–Barr virus (EBV).
Baldanzi, Bar, Bergsten, Bloch-Queyrat, Booth, Booth, Booth, Bottino, Candotti, Cannon, Cannons, Cannons, Cannons, Cannons, Chan, Chan, Chen, Chu, Chung, Coffey, Cohen, Crotty, Crotty, Czar, Das, Dong, Dong, Dupré, Dutz, Freeman, Gadue, Georgiadis, Ghosh, Gilmour, Grierson, Griewank, Harada, Harrington, Henter, Hislop, Holt, Hron, Jordan, Kageyama, Kanegane, Kim, Kohn, Lankester, Latour, Latour, Li, Loeffel, Ma, Ma, Marsh, Marsh, McCausland, Mejstríková, Menard, Milone, Morra, Nakajima, Nichols, Nichols, Nichols, Ochs, Pachlopnik Schmid, Palendira, Palendira, Parolini, Pasquier, Pawson, Porteus, Poy, Provisor, Purtilo, Purtilo, Qasim, Qi, Rigaud, Rivat, Rougemont, Ruffo, Sayos, Schwartzberg, Seemayer, Sepulveda, Shlapatska, Snow, Sullivan, Sumegi, Sumegi, Talaat, Tangye, Tangye, Tangye, Thorley-Lawson, Veillette, Victora, Worth, Wu, Wu, Wu, Yin, Zhang, Zhao   +105 more
core   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Disseminated tuberculosis and hemophagocytic syndrome although TB prophylaxis in patients with inflammatory bowel disease treated with Infliximab

IDCases, 2019
Purpose: We present de case of a 27-year-old woman admitted to ICU after scheduled splenectomy to study her short course of fever, leukopenia and splenic space-occupying lesions and splenomegaly.
Modesto Martínez-Pillado, Marina Varela-Durán, Ismael Said-Criado, Pilar Díaz-Parada, María Rodríguez-Losada, María Mendoza-Pintos   +5 more
doaj   +1 more source

Loomulike tappurrakkude aktiivsuse tsütomeetriline määramine [PDF]

, 2008
Loomulikud tappurrakud (ingl natural killers, NK) on loomulikku immuunsust tagavad lümfotsüüdid, mis on võimeli­sed hävitama teisi rakke ilma eelneva immunoloogilisekogemuseta.
Aints, Alar, Everaus, Hele, Štšerbakova, Anna   +2 more
core   +2 more sources

Treatment-refractory immune checkpoint inhibitor-induced hemophagocytic lymphohistiocytosis in the setting of adjuvant pembrolizumab for resected stage IIC melanoma: a case report

Journal of Medical Case Reports
Background Hemophagocytic lymphohistiocytosis is rare and does not have any distinct clinical features or laboratory abnormalities, whereby a high index of suspicion is required for diagnosis.
Kar Ven Cavan Chow, Kimberley Mui, Stewart Hunt, Chun Loo Gan   +3 more
doaj   +1 more source

Secondary hemophagocytic lymphohistiocytosis in a child with Leptospira infection: A case report

The Turkish Journal of Pediatrics, 2018
Leptospirosis caused by spirochetes of the genus Leptospira in most patients result in very mild illness without jaundice. However, a small portion of patients develop various complications due to the involvement of multiple organ systems ...
Dragana Jevtic, Dragomir Djokic, Danka Redzic, Dragana Aleksic, Miro Parezanovic, Srdjan Pasic   +5 more
doaj   +1 more source

Genetic dissection of NK cell responses [PDF]

, 2013
The association of Natural Killer (NK) cell deficiencies with disease susceptibility has established a central role for NK cells in host defence. In this context, genetic approaches have been pivotal in elucidating and characterizing the molecular ...
Jennifer Marton, Nassima Fodil-Cornu, Peter Moussa, Silvia M. Vidal   +3 more
core   +2 more sources

Secondary Dengue Infection Complicated by Hemophagocytic Lymphohistiocytosis: A Case Report

Case Reports in Infectious Diseases
Hemophagocytic lymphohistiocytosis is a fatal hyperinflammatory disorder in which CD8+ cytotoxic T-cells, natural killer cells, and macrophages destroy hematopoietic cells and vital organs. Viral infections, such as Epstein–Barr virus, are known to cause
Dominique D. Davis, Saffett Guleryuz, Yehuda Galili, Pablo A. Bejarano   +3 more
doaj   +1 more source

Hemophagocytic lymphohistiocytosis presenting in a pediatric patient with near total colonic and small bowel aganglionosis: a case report

Journal of Medical Case Reports, 2017
Background Total colonic and small bowel aganglionosis is a rare condition typically requiring intestinal transplant for long-term survival. There have not been any previously reported cases of near total intestinal aganglionosis complicated by concerns ...
Brittany Badal, Michael J. Wilsey, Sara Karjoo   +2 more
doaj   +1 more source