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Hemophagocytic lymphohistiocytosis in adults
Dear Sir, I read with interest a recent article by Antonodimitrakis and colleagues in your journal presenting a case of acquired hemophagocytic lymphohistiocytosis (HLH) in a 60-year-old woman suffering from diabetes mellitus type 2 (1). The reported patient developed a life-threatening HLH associated with a reactivation of an Epstein–Barr virus ...
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Primary Hemophagocytic Lymphohistiocytosis in a Newborn Child
The article presents the data of clinical observation of hemophagocytic lymphohistiocytosis in newborn child, complicated with spontaneous splenic rupture. Issues of diagnosis according to the recommendations of the International society for the study of
T.A. Khalturina +7 more
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ABSTRACT Posaconazole is a triazole antifungal agent used for prophylaxis and treatment of invasive fungal diseases. Posaconazole has high inter‐individual variability in dose‐exposure relationship and benefits from therapeutic drug monitoring (TDM). Adult studies report particularly high rates of subtherapeutic exposure among intensive care unit (ICU)
Kathryn Pavia +2 more
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Albayrak, Meryem/0000-0003-2711-5150Objectives: Hemophagocytic lymphohistiocytosis is a syndrome of pathologic immune activation that shares similar clinical and laboratory phenotypes with severe sepsis.
Albayrak, Meryem +5 more
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Secondary hemophagocytic lymphohistiocytosis in a patient with severe leptospirosis: a case report
Background Hemophagocytic lymphohistiocytosis is a rare but life-threatening hyperinflammatory syndrome that can be triggered by infections, malignancies, and autoimmune diseases.
Mariana R. Basurto-Hurtado +3 more
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Familial hemophagocytic lymphohistiocytosis [PDF]
T E, Herman, M J, Siegel
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CASE REPORT Familial Hemophagocytic Lymphohistiocytosis in Two Brothers
Familial hemophagocytic lymphohistiocytosis is a disorder which presents with fever, pancytopenia, liver dysfunction and also an increase in non-malignant histiocytes with prominent hemophagocytosis in various organs.
Medical Centre +2 more
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Hemophagocytic lymphohistiocytosis
Hemophagocytic lymphohistiocytosis (HLH) is a syndrome characterized by inappropriately activated lymphocytesand natural killer cells that produce high concentrations of cytokines. It is evidenced that "hypercytokinemia"and subsequently uncontrolled activation of histiocytes/ macrophages and T-lymphocytes underline the progressiveorgan dysfunction ...
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The article presents a clinical case of successful application of high doses of normal human immunoglobulin in a patient with secondary hemophagocytic syndrome associated with adenovirus infection, who was in the clinic of infectious diseases of the ...
A. A. Selʹkina +10 more
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Hemophagocytic lymphohistiocytosis is a syndrome of immune dysregulation that can lead to an overwhelming inflammatory state. In this case series, we describe 3 cases in which disseminated Histoplasma capsulatum infection caused hemophagocytic ...
Maki, Gina +3 more
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