Results 41 to 50 of about 415,767 (291)
Of mice and lymphoid aggregates: modeling tertiary lymphoid structures in cancer
Frontiers in Immunology, 2023 Tertiary lymphoid structures (TLS) are lymph node-like aggregates that can form in association with chronic inflammation or cancer. Mature TLS are organized into B and T cell zones, and are not encapsulated but include all cell types necessary for eliciting an adaptive immune response.
Vaccaro, Alessandra +4 more
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Epigenetic Activation of SOX11 in Lymphoid Neoplasms by Histone Modifications [PDF]
, 2011 Recent studies have shown aberrant expression of SOX11 in various types of aggressive B-cell neoplasms. To elucidate the molecular mechanisms leading to such deregulation, we performed a comprehensive SOX11 gene expression and epigenetic study in stem ...
Amador Virginia +107 more
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Innate lymphoid cells and cancer
, 2022 International audienceThe innate lymphoid cell (ILC) family is composed of natural killer (NK) cells, ILC1, ILC2 and ILC3, which participate in immune responses to virus, bacteria, parasites and transformed cells.
Vivier, Eric +3 more
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MIXED HYALINE VASCULAR AND PLASMA CELL TYPE CASTLEMAN’S DISEASE: REPORT OF A CASE [PDF]
Acta Medica Iranica, 2006 Castleman’s disease (angiofollicular lymphoid hyperplasia) includes a heterogeneous group of lymphoproliferative disorders. The cause of this disease remains uncertain.
F. Asgarani +4 more
doaj +1 more source
Lymphoid Neogenesis and Tertiary Lymphoid Organs in Transplanted Organs [PDF]
Frontiers in Immunology, 2016 The progressive organization of immune effectors into functional ectopic lymphoid structures, named tertiary lymphoid organs (TLO), has been observed in many conditions in which target antigens fail to be eliminated by the immune system. Not surprisingly, TLO have been recurrently identified in chronically rejected allografts.
Koenig, Alice, Thaunat, Olivier
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Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy [PDF]
, 2014 Helminth parasites such as the nematode Heligmosomoides polygyrus strongly inhibit T helper type 2 (Th2) allergy, as well as colitis and autoimmunity. Here, we show that the soluble excretory/secretory products of H.
McSorley, H. J.; id_orcid +15 more
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Castle man disease: a case report and review of the literature
The Pan African Medical Journal, 2014 The Castleman disease (CD) is a rare disease of unknown etiology, characterized histologically by angiofollicular lymphoid hyperplasia. It comes in two forms, unicentric and multicentric.
Mounir Kettani +6 more
doaj +1 more source
Innate lymphoid cells in secondary lymphoid organs
Immunological Reviews, 2016 SummaryThe family of innate lymphoid cells (ILCs) has attracted attention in recent years as its members are important regulators of immunity, while they can also cause pathology. In both mouse and man, ILCs were initially discovered in developing lymph nodes as lymphoid tissue inducer (LTi) cells.
Bar-Ephraïm, JE, Mebius, Reina E.
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Journal for ImmunoTherapy of Cancer, 2021 Background Full application of cytokines as oncoimmunotherapeutics requires identification of optimal regimens. Our initial effort with intravenous bolus recombinant human interleukin-15 (rhIL-15) was limited by postinfusional reactions.
Thomas A Waldmann +11 more
doaj +1 more source
Interplay between inflammation, autoimmunity and regeneration in the NOD mouse model of type 1 diabetes and Sjogren’s Syndrome. [PDF]
, 2011 PhDA continuous process of tissue remodelling and regeneration is a fundamental feature of the homeostatic response of the target organ of several autoimmune diseases.
Astorri, Elisa
core +4 more sources