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Primary mediastinal large B cell lymphoma (PMBCL) is an aggressive non-Hodgkin’s lymphoma, predominantly affecting young patients. We analyzed 45 primary PMBCL tumor biopsies and 3 PMBCL-derived cell lines for the presence of genetic alterations ...
Anja Mottok +16 more
doaj +1 more source
Characterization of lymphoid tissue inducer cells and lymphoid tissue development in adult interleukin 7 transgenic mice [PDF]
During embryogenesis, the development of secondary lymphoid organs (SLOs) such as lymph nodes (LNs) and Peyer’s patches (PPs) requires the cellular crosstalk between vascular cell adhesion molecule (VCAM)-1+ mesenchymal organizer cells and CD45+CD4 ...
Schmutz, Sandrine
core +1 more source
In situ characterisation of CD4+ t cell behaviour in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance [PDF]
The behavior of antigen-specific CD4+ T lymphocytes during initial exposure to antigen probably influences their decision to become primed or tolerized, but this has not been examined directly in vivo.
Cahalan, M. +12 more
core +4 more sources
The Role of T Lymphocytes in Skeletal Muscle Repair From Traumatic and Contraction-Induced Injury
Skeletal muscle is prone to damage from a range of stimuli, and initiates a robust repair process that requires the participation of immune cells. Among the more well characterized immune cells involved in muscle repair are those of the myeloid lineage ...
Michael R. Deyhle, Robert D. Hyldahl
doaj +1 more source
MALAT1 expression is associated with aggressive behavior in indolent B-cell neoplasms
MALAT1 long non-coding RNA has oncogenic roles but has been poorly studied in indolent B-cell neoplasms. Here, MALAT1 expression was analyzed using RNA-seq, microarrays or qRT-PCR in primary samples from clinico-biological subtypes of chronic lymphocytic
Elena María Fernández-Garnacho +17 more
doaj +1 more source
Immunophenotypic Aberrancies in Acute Leukemia: A Tertiary Care Centre Experience
Objectives: Acute leukemias (AL) are a heterogeneous group of hematological malignancies with the presence of 20% or more blasts in the peripheral blood or bone marrow.
Monika Gupta +5 more
doaj +1 more source
Background: Immunophenotyping improves both accuracy and reproducibility of acute leukemia classification and is considered, particularly useful for identifying acute myeloid leukemia (AML) with lymphoid marker expression.
Wafaa Mohammed Al-Anizi +1 more
doaj +1 more source
Primary mediastinal B-cell lymphoma (PMBL) is currently curable in 85–95% of patients. Treatment regimens frequently used include RCHOP ± radiotherapy, DAEPOCH-R, or occasionally more intensive protocols.
Joanna Romejko-Jarosinska +18 more
doaj +1 more source
The thymus and T-cell ontogeny in ballan wrasse (Labrus bergylta) is nutritionally modelled
Marine fish larvae often experience high mortality unrelated to predation during early life stages, and farmed ballan wrasse (Labrus bergylta) is no exception.
Angela Etayo +6 more
doaj +1 more source
Regulation of myeloid and lymphoid cell development by O-glycans on Notch
Notch signaling via NOTCH1 stimulated by Delta-like ligand 4 (DLL4) is required for the development of T cells in thymus, and NOTCH2 stimulated by Notch ligand DLL1 is required for the development of marginal zone (MZ) B cells in spleen.
Pamela Stanley, Ankit Tanwar
doaj +1 more source

