Gastric LTi cells promote lymphoid follicle formation but are limited by IRAK-M and do not alter microbial growth. [PDF]
Lymphoid tissue inducer (LTi) cells are activated by accessory cell IL-23, and promote lymphoid tissue genesis and antibacterial peptide production by the mucosal epithelium.
Banerjee, A+9 more
core +5 more sources
Synthesis of artificial lymphoid tissue with immunological function. [PDF]
The ability to generate functional artificial lymphoid tissue to induce specific immunity at ectopic sites could offer a potential breakthrough for treatment of diseases such as cancer and severe infection using immunotherapy.
Kobayashi, Yuka, Watanabe, Takeshi
core +1 more source
Transplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization [PDF]
In this report we describe a transplantation system where embryonic spleens are grafted into adult hosts. This model can be used to analyze the cellular and molecular requirements for the development and organization of splenic microenvironments.Whole ...
Aloisi+43 more
core +2 more sources
Coreceptor Choice and T Cell Depletion by R5, X4, and R5X4 HIV-1 Variants in CCR5-Deficient (CCR5Δ32) and Normal Human Lymphoid Tissue [PDF]
Coreceptor utilization by HIV-1 is an important determinant of pathogenesis. However, coreceptor selectivity is defined in vitro, while in vivo critical pathogenic events occur in lymphoid tissues.
Collman, Ronald G.+9 more
core +1 more source
Antigen-presenting cells and antigen presentation in tertiary lymphoid organs [PDF]
Tertiary lymphoid organs (TLOs) form in territorialized niches of peripheral tissues characterized by the presence of antigens; however, little is known about mechanism(s) of antigen handling by ectopic lymphoid structures.
Bedaj, Marija+3 more
core +1 more source
Association between malaria exposure and Kaposi's sarcoma-associated herpes virus seropositivity in Uganda. [PDF]
OBJECTIVE: Unlike other herpes viruses, Kaposi's sarcoma-associated herpes virus (KSHV) is not ubiquitous worldwide and is most prevalent in sub-Saharan Africa. The reasons for this are unclear. As part of a wider investigation of factors that facilitate
Cose, Stephen+8 more
core +2 more sources
Enrichment of innate lymphoid cell populations in gingival tissue [PDF]
Innate lymphoid cells (ILCs) are a population of lymphocytes that act as the first line of immunologic defense at mucosal surfaces. The ILC family in the skin, lungs, and gastrointestinal tissues has been investigated, and there are reports of individual
Adrados Planell, A.+5 more
core +2 more sources
Tissue Tropism in Host Transcriptional Response to Members of the Bovine Respiratory Disease Complex. [PDF]
Bovine respiratory disease (BRD) is the most common infectious disease of beef and dairy cattle and is characterized by a complex infectious etiology that includes a variety of viral and bacterial pathogens.
Behura, Susanta K+11 more
core +3 more sources
Zebrafish Caudal Haematopoietic Embryonic Stromal Tissue (CHEST) Cells Support Haematopoiesis. [PDF]
Haematopoiesis is an essential process in early vertebrate development that occurs in different distinct spatial locations in the embryo that shift over time.
Aggio, Julian+6 more
core +1 more source
HiJAKing innate lymphoid cells? [PDF]
The family of innate lymphoid cells (ILCs) consists of a heterogeneous group of cytokine-producing cells that have features in common with adaptive T helper (Th) cells.
Gadina, Massimo+2 more
core +1 more source