Results 101 to 110 of about 375,831 (354)
Advances and Strategies in Enhancing mRNA Cancer Vaccines
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang+4 more
wiley +1 more source
Aim - presents data on the number of cells of the lymphoid series and the cellular composition of the lymphoid tissue in the mucosa of the vaginal vestibule at different age periods of ontogenesis. Materials and methods.
S. V. Shadlinskaya
doaj +1 more source
Transcript Identification Using Arrayed Hydrogels With TrapFISH
TrapFISH is a novel method for high‐throughput single‐cell transcriptomics. It embeds cells in hyaluronic acid hydrogel beads and uses probe hybridization to quantify custom gene panels. By arraying hydrogels in microfluidic devices, cell barcoding is removed, enhancing scalability for studying cellular heterogeneity and rare cell states by targeting ...
David B. Morse+5 more
wiley +1 more source
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen+2 more
wiley +1 more source
The Lymphoid Tissue and Antibody Formation
SummaryAdrenalectomized rabbits with hypertrophy of the lymphoid tissues produce antibodies in amounts far in excess of that produced by intact animals. this is evident not only by definite reactions in higher dilution but by the more masive precipitate in low dilutions.
James B. Murphy, Ernest Sturm
openaire +3 more sources
Type 2 innate lymphoid cell and kidney disease
Innate lymphoid cells(ILCs)are a newly-discovered family of immune cells in innate immunity with acquired immune function.Usually located at mucosal barriers, they mediate early immunosurveillance and regulate immune responses through secreting cytokines.
Yao Deng-hu+2 more
doaj
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi+5 more
wiley +1 more source
Uterine natural killer cell heterogeneity: Lessons from mouse models [PDF]
Natural killer (NK) cells are the most abundant lymphocytes at the maternal-fetal interface. Epidemiological data implicate NK cells in human pregnancy outcomes.
Sojka, Dorothy K
core +1 more source
EXPERIMENTS ON THE RÔLE OF LYMPHOID TISSUE IN THE RESISTANCE TO EXPERIMENTAL TUBERCULOSIS IN MICE [PDF]
James B. Murphy, Ernest Sturm
openalex +1 more source
Cytokine Engineering Approaches for Regenerative Medicine
Engineered cytokines represent a powerful strategy to promote tissue repair and regeneration by precisely modulating immune responses. This review highlights recent advances in cytokine engineering, including strategies to enhance half‐life, improve tissue and cell targeting, and control receptor signaling.
Shiyi Li, Wenhao You, Mikaël M. Martino
wiley +1 more source