Results 41 to 50 of about 381,885 (288)

Lymphoid tissue inducer cells [PDF]

open access: yesCurrent Biology, 2011
What are they? Lymphoid tissue inducer (LTi) cells are a hematopoietic cell type with critical roles in the immune system during both the embryonic and adult stages of development. Their distinguishing features are expression of RORγt and IL-7Rα in the absence of lineage markers (e.g. CD3, CD19, B220, CD11c, Gr-1).
openaire   +2 more sources

Perivascular adipose tissue inflammation in vascular disease [PDF]

open access: yes, 2017
Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in volume and becomes dysfunctional, with altered cellular composition and molecular ...
Guzik, Tomasz J., Nosalski, Ryszard
core   +1 more source

Characteristics of intestinal-related lymphoid hyperplasia in children and its correlation with intussusception of children

open access: yesBMC Pediatrics, 2022
Background Primary intussusception in children is a common acute abdominal disease. The cause of this disease is still not fully understood. Many articles have reported that children with intussusception are often accompanied by hyperplasia of mesenteric
Qingtao Yan   +4 more
doaj   +1 more source

Editorial: tertiary lymphoid organs (TLOs): powerhouses of disease immunity [PDF]

open access: yes, 2017
No abstract ...
Habenicht, Andreas J.R.   +3 more
core   +2 more sources

Tissue Tregs and Maintenance of Tissue Homeostasis

open access: yesFrontiers in Cell and Developmental Biology, 2021
Regulatory T cells (Tregs) specifically expressing Forkhead box P3 (Foxp3) play roles in suppressing the immune response and maintaining immune homeostasis.
Qing Shao   +27 more
doaj   +1 more source

Transplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization [PDF]

open access: yes, 2009
In this report we describe a transplantation system where embryonic spleens are grafted into adult hosts. This model can be used to analyze the cellular and molecular requirements for the development and organization of splenic microenvironments.Whole ...
Rennert   +43 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. [PDF]

open access: yes, 2016
Group 2 innate lymphoid cells (ILC2s) and type 2 helper T cells (Th2 cells) are the primary source of interleukin 5 (IL-5) and IL-13 during type 2 (allergic) inflammation in the lung.
Austen, K Frank   +5 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Formation of immune structures in small intestine of Muscovy ducks (Cairina moschata)

open access: yesTheoretical and Applied Veterinary Medicine, 2020
Of particular importance in our time is the detailed study of morphology, physiology and biochemistry, the digestive system of new poultry crosses, which is the biological basis for the development of complete feeding and improving the productive ...
V. V. Logvinova   +2 more
doaj   +1 more source

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