Results 1 to 10 of about 35,966 (245)

Recent advances in adoptive cell therapy for cancer immunotherapy [PDF]

open access: yesFrontiers in Immunology
Adoptive cell therapy (ACT), a key direction in tumor immunotherapy, has achieved remarkable progress in recent years. This paper systematically reviews the current status and future trends of ACT, covering lymphokine-activated killer cells (LAK), tumor ...
Jiameng Qian   +3 more
doaj   +2 more sources

Regulation of T cell lymphokine production by killer cell inhibitory receptor recognition of self HLA class I alleles. [PDF]

open access: hybrid, 1996
The killer cell inhibitory receptors (KIRs) are surface glycoproteins expressed by natural killer (NK) and T cells that specifically recognize defined groups of polymorphic human histocompatibility leukocyte antigen (HLA) class I molecules.
Chang, C   +3 more
core   +3 more sources

CAR T cell therapy for central nervous system solid tumors: current progress and future directions [PDF]

open access: yesFrontiers in Immunology
Central nervous system (CNS) tumors are the second most common type of cancer in children and remain the leading cause of mortality in pediatric oncology.
Yaroslav Kaminskiy   +3 more
doaj   +2 more sources

Evolution of cell therapy for renal cell carcinoma [PDF]

open access: yesMolecular Cancer
Treatment for renal cell carcinoma (RCC) has improved dramatically over the last decade, shifting from high-dose cytokine therapy in combination with surgical resection of tumors to targeted therapy, immunotherapy, and combination therapies.
Yufei Wang   +9 more
doaj   +2 more sources

Lymphokine-activated killer cell transplantation after anti-cancer treatment in two aged cats [PDF]

open access: yesOpen Veterinary Journal, 2019
Immunotherapy improves both survival and remission rates after cancer surgery in humans, but its veterinary use has been limited. We determined the safety and feasibility of lymphokine-activated killer (LAK) cell transplantation in two aged cats that had
Noritaka Maeta   +3 more
doaj   +1 more source

The role of egg antigens, cytokines in granuloma formation in murine schistosomiasis mansoni

open access: yesMemorias do Instituto Oswaldo Cruz, 1992
The induction of granuloma formation by soluble egg antigens (SEA) of Schistosoma mansoni is accompanied by T cell-mediated lymphokine production that regulates the intensity of the response.
Dov L. Boros, Nicholas W. Lukacs
doaj   +1 more source

Battle of Thermopylae: 300 Spartans (natural killer cells plus obinutuzumab) versus the immortal warriors (chronic lymphocytic leukemia cells) of Xerxes’ army

open access: yesFuture Science OA, 2019
Aim: To analyze the effects of subcutaneous or intravenous rituximab + lymphokine-activated killer cells, obinutuzumab or ibrutinib on natural killer (NK) cell levels in chronic lymphocytic leukemia and follicular lymphoma patients.
Ricardo García-Muñoz   +15 more
doaj   +1 more source

Mouse Ocilrp2/Clec2i negatively regulates LPS-mediated IL-6 production by blocking Dap12-Syk interaction in macrophage

open access: yesFrontiers in Immunology, 2022
C-type lectin Ocilrp2/Clec2i is widely expressed in dendritic cells, lymphokine-activated killer cells and activated T cells. Previous studies have shown that Ocilrp2 is an important regulator in the activation of T cells and NK cells.
Mingya Cao   +12 more
doaj   +1 more source

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism. [PDF]

open access: yes, 1990
BALB/c mice infected with Leishmania major develop fatal, progressive disease, despite an immune response characterized by expansion of CD4+ T cells in the draining lymph nodes.
Dawkins, RS   +5 more
core   +1 more source

Intraperitoneal biotherapy of malignant peritoneal effusions in ovarian cancer patients

open access: yesОпухоли женской репродуктивной системы, 2014
Malignant peritoneal effusions often arise in patients with of ovarian cancer. They are dangerous complication of cancer. Intraperitoneal chemotherapy isn’t always effective and causes side effects.
К. S. Titov   +5 more
doaj   +1 more source

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