Results 31 to 40 of about 15,433 (212)
Cell Proliferation, Volume 58, Issue 4, April 2025.This manuscript provides a comprehensive overview of the state‐of‐the‐art in non‐viral CAR‐NK cell engineering, highlighting its potential to revolutionise cancer treatment. ABSTRACT The recent advancements in cancer immunotherapy have spotlighted the potential of natural killer (NK) cells, particularly chimeric antigen receptor (CAR)–transduced NK ...
Zhaokai Zhou +18 more
wiley +1 more source
The role of HuR in the post-transcriptional regulation of interleukin-3 in T cells. [PDF]
PLoS ONE, 2014 Human Interleukin-3 (IL-3) is a lymphokine member of a class of transiently expressed mRNAs harboring Adenosine/Uridine-Rich Elements (ARE) in their 3' untranslated regions (3'-UTRs).
José A González-Feliciano +10 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 BackgroundSkin cancer is one of the most commonly diagnosed cancers worldwide. The 5-year survival rate of the most aggressive late-stage skin cancer ranges between 20 and 30%. Thus, the discovery and investigation of novel target therapeutic agents that
Xiaorong Fu +20 more
doaj +1 more source
Biological processes and factors involved in soft and hard tissue healing
Periodontology 2000, Volume 97, Issue 1, Page 16-42, February 2025.Abstract Wound healing is a complex and iterative process involving myriad cellular and biologic processes that are highly regulated to allow satisfactory repair and regeneration of damaged tissues. This review is intended to be an introductory chapter in a volume focusing on the use of platelet concentrates for tissue regeneration.
Mark Bartold, Saso Ivanovski
wiley +1 more source
PPARγ induces PD-L1 expression in MSS+ colorectal cancer cells
OncoImmunology, 2021 Only a small subset of colorectal cancer (CRC) patients benefits from immunotherapies, comprising blocking antibodies (Abs) against checkpoint receptor “programmed-cell-death-1” (PD1) and its ligand (PD-L1), because most cases lack the required ...
Tobias Gutting +21 more
doaj +1 more source
PBK/TOPK: A Therapeutic Target Worthy of Attention
Cells, 2021 Accumulating evidence supports the role of PDZ-binding kinase (PBK)/T-lymphokine-activated killer-cell-originated protein kinase (TOPK) in mitosis and cell-cycle progression of mitotically active cells, especially proliferative malignant cells.
Ziping Han +4 more
doaj +1 more source
Adoptive cell transfer: new perspective treatment in veterinary oncology
Acta Veterinaria Scandinavica, 2018 Cancer immunotherapy is recently considered the most promising treatment for human patients with advanced tumors and could be effectively combined with conventional therapies such as chemotherapy or radiotherapy.
Joanna Katarzyna Bujak +3 more
doaj +1 more source
Health Science Reports, Volume 8, Issue 1, January 2025.ABSTRACT Background and Aims Dengue is a mosquito‐borne viral disease that frequently causes seasonal outbreaks in Bangladesh, particularly during the monsoon months from June to September. Recent outbreaks have shown significant shifts in clinical manifestations, including changes in the timeframe and serotype mixing.
Md. Jubayer Hossain +4 more
wiley +1 more source
The LIN28B–let‐7–PBK pathway is essential for group 3 medulloblastoma tumor growth and survival
Molecular Oncology, 2023 Children with Group 3 medulloblastoma (G3 MB) have a very poor prognosis, and many do not survive beyond 5 years after diagnosis. A factor that may contribute to this is the lack of available targeted therapy.
Shubin W. Shahab +12 more
doaj +1 more source
An arthritogenic lymphokine in the rat. [PDF]
The Journal of experimental medicine, 1985 A type II collagen-specific arthritogenic lymphokine has been identified in the rat. Arthritogenic factor (AF) is a 65 kD protein generated in vitro by T cells from rats with collagen arthritis, and it induces an erosive, proliferative synovitis when injected into the knee joint of syngeneic naive recipients.
David E. Trentham +3 more
openaire +3 more sources