Results 61 to 70 of about 42,616 (282)

Primary Orbital Lymphoma – A Challenging Diagnosis

Acta Medica Bulgarica, 2020
Background and purpose: The occurrence of primary orbital lymphoma comprises approximately 1% of non-Hodgkin’s lymphoma and 8% of extranodal lymphoma. The vast majority of orbital lymphomas are of B-cell origin, of which extranodal marginal zone B-cell ...
Vylkanov St., Trifonova K., Slaveykov K., Dzhelebov D.   +3 more
doaj   +1 more source

Gastric cancer is the leading cause of death in Italian adult patients with common variable immunodeficiency [PDF]

, 2018
An increased prevalence of malignant lymphoma and of gastric cancer has been observed in large cohorts of patients with common variable immunodeficiency (CVID), the most frequently symptomatic primary immunodeficiency. Surveillance strategies for cancers
Agostini, Carlo, Cinetto, Francesco, Crescenzi, Ludovica, Milito, Cinzia, Pecoraro, Antonio, Pulvirenti, Federica, Quinti, Isabella, Rizzo, Francesca, Santangeli, Enrico, Spadaro, Giuseppe, Tabolli, Stefano, Valente, Michele   +11 more
core   +3 more sources

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies [PDF]

, 2010
Sequence variants at the TERT-CLPTM1L locus in chromosome 5p have been recently associated with disposition for various cancers. Here we show that this locus including the gene encoding the telomerase reverse-transcriptase TERT at 5p13.33 is rarely but ...
Akasaka, T. (T.), Ammerpohl, O. (Ole), Callet-Bauchu, E. (E.), Dyer, M.J.S. (Martin J. S.), Gascoyne, R.D (R. D.), Gesk, S. (Stefan), Harder, L. (Lana), Horsman, D. (D.), Klapper, W. (Wolfram), Majid, A. (Aneela), Martin-Subero, J.I. (Jose Ignacio), Martinez-Climent, J.A. (José Ángel), Nagel, I. (Inga), Siebert, R. (Reiner), Stilgenbauer, S. (Stepahn), Szczepanowski, M. (Monika), Tönnies, H. (Holger)   +16 more
core  

Clinicopathological features of extranodal lymphomas: Kuwait experience [PDF]

, 2004
A total of 935 patients with extranodal non-Hodgkin lymphoma (NHL) diagnosed in the period between January 1985 and December 2000 in Kuwait Cancer Center, serving the whole population of Kuwait, were used to describe the clinicopathological and ...
Bamanikar S, D'Amore F, Ducreux M, F. Sinowatz, Freeman C, Gospodarowicz MK, H. Amanguno, H. Baker, Hauke RJ, J.P. Madda, L. Temmim, Longo DL, Neugut AI, Penn I, Shome DK, Stiller CA, Weisenburger DD, Zeeb H   +17 more
core   +1 more source

An Investigation of Hyperostosis Frontalis Interna in a Modern Anatomical Body Donor Population

Clinical Anatomy, EarlyView.
ABSTRACT This research sought to examine the prevalence and severity of hyperostosis frontalis interna (HFI) in the Chicagoland anatomical body donor population. The study further aimed to elucidate potential demographic risk factors for HFI, including sex, age at death, and structural vulnerability index (SVI), as well as any common comorbidities, as ...
Amy C. Beresheim, Amanda Hall
wiley   +1 more source

Primary Breast Lymphoma in a 30-Year-Old Female Patient: A MALT Lymphoma or Pediatric Nodal Marginal Zone Lymphoma? A Case Report and Literature Review

Клиническая онкогематология
Primary lymphoma accounts for less than 0.5 % of all breast malignancies. One of the most ubiquitous diseases in this group is extranodal lymphoma of mucosa-associated marginal zone lymphoid tissue (MALT lymphoma).
Mariya Vladimirovna Melnikova, A. M. Kovrigina   +1 more
doaj   +1 more source

Combinations of idelalisib with rituximab and/or bendamustine in patients with recurrent indolent non-Hodgkin lymphoma [PDF]

, 2016
Key Points Combining phosphatidylinositol-3-kinase δ inhibition with rituximab, bendamustine, or both is feasible and active in relapsed iNHL.
Barrientos, Jacqueline C., Boccia, Ralph V., Boyd, Thomas E., Coutre, Steven E., de Vos, Sven, Flinn, Ian W., Fowler, Nathan H., Furman, Richard R., Godfrey, Wayne R., Kim, Yeonhee, Leonard, John P., Rai, Kanti R., Schreeder, Marshall T., Sharman, Jeff P., Wagner-Johnston, Nina D.   +14 more
core   +2 more sources

Machine Learning for Predictive Modeling in Nanomedicine‐Based Cancer Drug Delivery

Med Research, EarlyView.
The integration of AI/ML into nanomedicine offers a transformative approach to therapeutic design and optimization. Unlike conventional empirical methods, AI/ML models (such as classification, regression, and neural networks) enable the analysis of complex clinical and formulation datasets to predict optimal nanoparticle characteristics and therapeutic
Rohan Chand Sahu, Sanchit Arora, Dinesh Kumar, Ashish Kumar Agrawal   +3 more
wiley   +1 more source

Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma [PDF]

, 2009
Signaling through the Notch1 receptor has a pivotal role in early thymocyte development. Gain of Notch1 function results in the development of T-cell acute lymphoblastic leukemia in a number of mouse experimental models, and activating Notch1 mutations ...
Chiba Shigeru, Fukayama Masashi, Hangaishi Akira, Izutsu Koji, Kumano Keiki, Kurokawa Mineo, Lee Suk-young, Matsumoto Akihiko, Nakazaki Kumi, Nannya Yasuhito, Ogawa Seishi, Ota Satoshi, Ota Yasunori, Sakata-Yanagimoto Mamiko, Sanada Masashi, Seto Masao, Suzuki Ritsuro, Yagita Hideo, Yamamoto Go, 千葉 滋, 坂田（柳元） 麻実子   +20 more
core   +1 more source