Results 71 to 80 of about 2,347,326 (232)

Ibrutinib in B-cell lymphoma: single fighter might be enough?

Cancer Cell International, 2020
Background In recent years, the B cell receptor (BCR) signaling pathway has become a “hot point” because it plays a critical role in B-cell proliferation and function. Bruton’s tyrosine kinase (BTK) is overexpressed in many subtypes of B-cell lymphoma as
Chao Xue, Xin Wang, Lingyan Zhang, Qingyuan Qu, Qian Zhang, Yujie Jiang   +5 more
doaj   +1 more source

Development of a novel cell line‐derived xenograft model of primary herpesvirus 8‐unrelated effusion large B‐cell lymphoma and antitumor activity of birabresib in vitro and in vivo

Cancer Medicine, 2021
Background Primary human herpesvirus 8 (HHV8)‐unrelated effusion large B‐cell lymphoma is a clinical disease entity distinct from HHV8‐positive primary effusion lymphoma (PEL).
Tomohiro Nishimori, Tomonori Higuchi, Yumiko Hashida, Takako Ujihara, Ayuko Taniguchi, Fumiya Ogasawara, Naoya Kitamura, Ichiro Murakami, Kensuke Kojima, Masanori Daibata   +9 more
doaj   +1 more source

Metagenomic deep sequencing of aqueous fluid detects intraocular lymphomas. [PDF]

, 2017
IntroductionCurrently, the detection of pathogens or mutations associated with intraocular lymphomas heavily relies on prespecified, directed PCRs. With metagenomic deep sequencing (MDS), an unbiased high-throughput sequencing approach, all pathogens as ...
Acharya, Nisha, Bloomer, Michele, DeRisi, Joseph L, Doan, Thuy, Gonzales, John, Shantha, Jessica G, Wilson, Michael R   +6 more
core   +1 more source

EBV Positive Diffuse Large B Cell Lymphoma with Negative Pan-B Cell Markers, Case Report, and Literature Review

Case Reports in Hematology
Most B cell lymphomas are positive for one or more B cell markers including CD19, CD20, CD79a, or PAX5. However, rare cases of mature B cell lymphoma not expressing any B cell markers have been characterized and recognized as distinct diagnostic entities
Janna Shold, Lea Jukic, Daniel Farrell, Wei Cui, Da Zhang   +4 more
doaj   +1 more source

T-cell/histiocyte-rich large B-cell lymphoma presenting as a primary central nervous system lymphoma

Rare Tumors, 2015
Primary central nervous system (PCNSL) lymphoma is an aggressive extranodal non-Hodgkin lymphoma, and most cases are classified as diffuse large B-cell lymphoma (DLBCL) by histology.
Pooja Advani, Jason Starr, Abhisek Swaika, Liuyan Jiang, Yushi Qiu, Zhimin Li, Han W. Tun   +6 more
doaj   +1 more source

Combined detection of lymphocyte clonality and MALT1 translocations in bronchoalveolar lavage fluid for diagnosing pulmonary lymphomas

Scientific Reports, 2021
Diagnosis of pulmonary lymphoma using small tissue samples is difficult and often requires surgical procedures; thus, a less invasive sampling method is desirable.
Takashi Kido, Hiroshi Ishimoto, Hiroshi Ishii, Kanako Hara, Mutsumi Ozasa, Hiroki Kawabata, Toshinori Kawanami, Yu Suzuki, Hiroki Yoshikawa, Atsuko Hara, Noriho Sakamoto, Nobuhiro Matsumoto, Chiharu Yoshii, Junya Fukuoka, Masaki Fujita, Masamitsu Nakazato, Junichi Kadota, Hiroshi Mukae, Kazuhiro Yatera   +18 more
doaj   +1 more source

Human leukocyte antigens and genetic susceptibility to lymphoma [PDF]

, 2015
Familial aggregation, coupled with ethnic variation in incidence, suggests that inherited susceptibility plays a role in the development of lymphoma, and the search for genetic risk factors has highlighted the contribution of the human leukocyte antigen (
Jarrett, R.F., McAulay, K.A.
core   +1 more source

CAR T Cell Toxicity: Current Management and Future Directions

HemaSphere, 2019
. By late 2018, 2 chimeric antigen receptor T (CAR T) cell products have been approved by US and European regulatory authorities. Tisagenlecleucel (Kymriah, Novartis) is indicated in the treatment of patients up to 25 years of age with B-cell acute ...
Lucrecia Yáñez, Miriam Sánchez-Escamilla, Miguel-Angel Perales   +2 more
doaj   +1 more source

Non-Hodgkin and Hodgkin Lymphomas Select for Overexpression of BCLW. [PDF]

, 2017
Purpose: B-cell lymphomas must acquire resistance to apoptosis during their development. We recently discovered BCLW, an antiapoptotic BCL2 family member thought only to contribute to spermatogenesis, was overexpressed in diffuse large B-cell lymphoma ...
Adams, Clare M., Eischen, Christine M., Gong, MD, Jerald Z., Mitra, Ramkrishna   +3 more
core   +1 more source

Protein kinase CK2 is widely expressed in follicular, Burkitt and diffuse large B-cell lymphomas and propels malignant B-cell growth. [PDF]

, 2015
Serine-threonine kinase CK2 is highly expressed and pivotal for survival and proliferation in multiple myeloma, chronic lymphocytic leukemia and mantle cell lymphoma.
Agostinelli, C, Benvenuti, P, Casellato, A, Fuligni, F, Mandato, E, Piazza, Francesco, Pileri, Sa, Pizzi, Marco, Rugge, Massimo, Semenzato, Gianpietro Carlo   +9 more
core   +1 more source