Results 61 to 70 of about 34,204 (229)

Extracavitary Manifestation of Primary Effusion Lymphoma as a Right Atrial Mass [PDF]

open access: yes, 2013
Primary effusion lymphoma (PEL) is a subset of large B cell lymphomas and has been mostly associated with human immunodeficiency virus infection. Rare cases have been reported in organ transplant recipients and chronic hepatitis C patients.
Guddati, Achuta K   +4 more
core   +2 more sources

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa   +3 more
wiley   +1 more source

HHV8‐unrelated primary effusion lymphoma in a patient with HBV‐related liver cirrhosis: A case successfully treated with rituximab and lenalidomide

open access: yesClinical Case Reports, 2023
Human herpesvirus type 8 (HHV‐8) unrelated primary effusion lymphoma (PEL) like lymphoma (PEL‐LL) is an exceedingly rare non‐Hodgkin lymphoma with no characteristic symptoms and consensus on the optimal treatment.
Peng‐Jun Liao   +2 more
doaj   +1 more source

Cytotoxic drugs activate KSHV lytic cycle in latently infected PEL cells by inducing a moderate ROS increase controlled by HSF1, NRF2 and p62/SQSTM1 [PDF]

open access: yes, 2018
Previous studies have indicated that cytotoxic treatments may induce or not activate viral lytic cycle activation in cancer cells latently infected by Kaposi’s sarcoma-associated herpesvirus (KSHV). To investigate the molecular mechanisms responsible for
Angiolillo, Camilla   +5 more
core   +1 more source

Analysis of interstitial lung disease in pharmacovigilance databases: Coding challenges and interpretation biases—An update

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Clinically, interstitial lung disease (ILD) is a heterogeneous group of respiratory disorders. Due to their low incidence, pharmacovigilance database analysis is useful to detect them. Precise diagnosis is challenging as well as coding in these databases. Query criteria are among the key elements for a good signal detection.
Romane Freppel   +4 more
wiley   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Suppression of KSHV lytic replication and primary effusion lymphoma by selective RNF5 inhibition.

open access: yesPLoS Pathogens, 2023
Primary effusion lymphoma (PEL), a rare aggressive B-cell lymphoma in immunosuppressed patients, is etiologically associated with oncogenic γ-herpesvirus infection.
Xiaojuan Li   +4 more
doaj   +1 more source

Long‐term cardiovascular outcomes of immune checkpoint inhibitor‐related myocarditis: A large single‐centre analysis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1237-1245, April 2025.
Abstract Aims Immune checkpoint inhibitors (ICI) are the cornerstone of modern oncology; however, side effects such as ICI‐related myocarditis (irM) can be fatal. Recently, Bonaca proposed criteria for irM; however, it is unknown if they correlate well with cardiovascular (CV) ICI‐related adverse events.
Lorenzo Braghieri   +12 more
wiley   +1 more source

Primary Effusion Lymphoma: A Rare and Challenging Diagnosis for Recurrent Pleural Effusion

open access: yesDiagnostics, 2023
Primary Effusion Lymphoma is an extremely rare and aggressive subtype of B-cell lymphoma, accounting for only
Letícia Jacome Pereira   +10 more
doaj   +1 more source

Upper Airway Obstruction due to Kaposi Sarcoma—Presenting Sign of HIV: Case Report and Review

open access: yesThe Laryngoscope, EarlyView.
This study presents a case of undiagnosed HIV presenting with Kaposi sarcoma (KS) of the head and neck with acute upper airway obstruction (UAO) and provides an updated scoping literature review to examine the patient characteristics, lesion characteristics, interventions, and outcomes of KS cases with UAO from the pharynx, larynx, and/or trachea.
Zachary A. Wykoff   +3 more
wiley   +1 more source

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