Results 81 to 90 of about 672,004 (247)

Smohaze‐Upregulated RFWD3 Competes with TRIM24 to Stabilize TREX1 and Reduce Cytosolic dsDNA in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
The E3 ubiquitin ligase RFWD3 binds the exonuclease TREX1 and protects it from TRIM24‐mediated ubiquitination and degradation, leading to the eradication of intracellular dsDNA, inhibition of the cGAS‐STING pathway, and immunosuppressive microenvironment of lung cancer.
Xue‐Yan Shi, Yu‐Ke Shen, Meng‐Yao Lv, Yu Sun, Yong‐Fang Lin, Zheng Wang, Xiao‐Liang Jie, Zheng Liu, Yang‐Tong Liu, Yang‐Xin Fu, Zhenhua Ren, Gui‐Zhen Wang, Guang‐Biao Zhou   +12 more
wiley   +1 more source

P1195: A PROSPECTIVE STUDY OF TARGETED SEQUENTIAL IMMUNOTHERAPY. IN PATIENTS WITH RELAPSED REFRACTORY PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA.

HemaSphere, 2023
Yuelu Guo, Kai Hu, Xiaoyan Ke, Teng Xu, Shaomei Feng, Peihao Zheng, Lixia MA, Fan Yang, Hui Shi, Biping Deng, Liu Rui, Zhonghua Fu   +11 more
doaj   +1 more source

Strategies for increasing accrual in cancer clinical trials: What is the evidence?

Cancer Medicine
Introduction Despite the importance of clinical trial participation among cancer patients, few participate—and even fewer patients from ethnic and racial minoritized groups.
Margo Michaels, Elisa S. Weiss, Maria Sae‐Hau, Dora Illei, Bethany Lilly, Leah Szumita, Brian Connell, Marialanna Lee, Eric Cooks, Melissa McPheeters   +9 more
doaj   +1 more source

Clinical and genomic features of macrofocal multiple myeloma: a distinct profile

Haematologica
Not available.
Jin Liu, Jianling Fan, Xinyi Zhou, Xi Chen, Xiaoli Hu, Haiyan He, Lina Jin, Weijun Fu, Jian Hou, Juan Du   +9 more
doaj   +1 more source

Intensive short‐term chemotherapy regimen induces high remission rate (over 90%) and event‐free survival both in children and adult patients with advanced sporadic Burkitt lymphoma/leukemia [PDF]

, 2011
Giuseppe Todeschini, Massimiliano Bonifacio, Cristina Tecchio, Rita Balter, Giuseppe Carli, Piero Maria Stefani, Fausto Adami, Alberto Zamò, Angelo Paolo Dei Tos, Filippo Marino, Filíppo Gherlinzoni, Pierluigi Marradi, Gianpietro Semenzato, Giovanni Pizzolo   +13 more
openalex   +1 more source

Multiscale Construction, Evaluation, and Application of Organoids

Advanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma, Zhenglin Dong, Zhu'anzhen Zheng, Long Bai, Xingcai Zhang, Jiacan Su   +5 more
wiley   +1 more source

EBV and 1q Gains Affect Gene and miRNA Expression in Burkitt Lymphoma [PDF]

, 2023
Nuray Akyüz, Snjezana Janjetovic, Susanne Ghandili, Carsten Bokemeyer, Judith Dierlamm   +4 more
openalex   +1 more source

B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns

Advanced Science, EarlyView.
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang, Youtao Wang, Cong Sun, Tao Liu, Zengfeng Wu, Lipeng Chen, Lina Chen, Penglin Li, Zhengkang Li, Cangui Zhang, Bingyun Lu, Ye Chen, Bing Gu, Qian Zhong, Xin Wei Wang, Mu‐Sheng Zeng, Jinping Liu   +16 more
wiley   +1 more source

Lack of serological evidence for an association between simian virus 40 and lymphoma [PDF]

, 2003
Sílvia de Sanjosé, Keerti V. Shah, Eva Domingo‐Doménech, Eric A. Engels, Alberto Fernández de Sevilla, Tomás Álvaro, Mercedes Garcia‐Villanueva, Vicens Romagosa, Eva González‐Barca, Raphael P. Viscidi   +9 more
openalex   +1 more source

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, EarlyView.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source