Results 11 to 20 of about 88,412 (297)

Rituximab-Containing Treatment Regimens May Imply a Long-Term Risk for Difficult-To-Treat Chronic Hepatitis E [PDF]

, 2020
Hepatitis E virus (HEV) infection is an emerging disease in industrialized countries which is usually characterized by a self-limited course. However, there is an increased risk of HEV persistence in immunocompromised risk populations, comprising ...
Biedermann, Paula, Bock, Claus-Thomas, Choi, Mira, Hanitsch, Leif Gunnar, Hofmann, Jörg, Mueller, Tobias, Schulz, Marten, Tacke, Frank   +7 more
core   +1 more source

Possible Mechanisms of Lymphopenia in Severe Tuberculosis

Microorganisms, 2023
Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (M. tuberculosis). In lymphopenia, T cells are typically characterized by progressive loss and a decrease in their count results.
Fei Li, Dandan Chen, Qingqing Zeng, Yunjie Du   +3 more
doaj   +1 more source

The Relationship between Severity of Lung Involvement Based on High-Resolution Computed Tomography (HRCT) Findings and Lymphopenia in Patients with COVID-19 [PDF]

Disease and Diagnosis, 2022
Background: Lymphopenia may reflect the degree of lung injury in patients with coronavirus disease 2019 (COVID-19). Given that few studies have been conducted in this regard, this study aimed to evaluate the association between severity of lung ...
Abolfazl Izadi, Fatemeh Khaleghi, Nasim Namiranian, Mohammad Cheraghipour, Kazem Ansari, Mehrdad Mansouri, Fatemeh Aghaeimeybodi   +6 more
doaj   +1 more source

Reduction of lymphocyte count at early stage elevates severity and death risk of COVID-19 patients: a hospital-based case-cohort study

Archives of Medical Science, 2020
Introduction Several reports have noted that severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) induced lymphopenia in coronavirus disease 2019 (COVID-19) patients. However, the clinical significance of lymphopenia remains unclear.
Jun Fei, Lin Fu, Ying Li, Hui-Xian Xiang, Ying Xiang, Meng-Die Li, Fang-Fang Liu, De-Xiang Xu, Hui Zhao   +8 more
doaj   +1 more source

Rapid recovery of postnivolumab vemurafenib-induced Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome after tocilizumab and infliximab administration [PDF]

, 2020
Background Immune checkpoint inhibitors such as nivolumab and targeted BRAF inhibitors have dramatically altered the treatment outcomes of metastatic melanoma over the past few years. Skin toxicity is the most common adverse event (AE) related to the
Maestro, Alessandra, Marcuzzi, Annalisa, Maximova, Natalia, Zanon, Davide   +3 more
core   +1 more source

Prognostic Value and Risk Factors of Treatment-Related Lymphopenia in Malignant Glioma Patients Treated With Chemoradiotherapy: A Systematic Review and Meta-Analysis

Frontiers in Neurology, 2022
Background: Immunotherapy has shown promising therapeutic efficacy in various cancers but not gliomas. Circulating lymphocytes play critical roles in cancer control and responses to immune checkpoint inhibitors.
Yongchao Zhang, Shichao Chen, Hualei Chen, Shanshan Chen, Zhen Li, Enshan Feng, Wei Li   +6 more
doaj   +1 more source

Severe lymphopenia as a prognostic factor in rectal cancer patients receiving adjuvant chemoradiotherapy: a retrospective study

Scientific Reports, 2023
The relationship between total lymphocyte counts (TLCs) and survival is not well documented in rectal cancer. This study aimed to investigate the association between TLCs and disease-free survival (DFS) and identify factors associated with lymphopenia in
Shuang Li, Weiping Yao, Ruiqi Liu, Yanwei Lu, Haibo Zhang, Xiaodong Liang   +5 more
doaj   +1 more source

Lymphopenia: A predictive marker of disease severity in COVID-19 infection [PDF]

Romanian Journal of Medical Practice, 2021
Background. With the latest COVID-19 deaths reported to WHO now exceeding 3.3 million, COVID-19 has developed into a milestone of our medical generation, causing disruption in communities and hospital services.
Georgeta Daniela Georgescu, Marius Balea, Viola Popov, Mihaela Andreescu, Mircea Munteanu, Mihaela Popescu, Oana Patrinoiu, Geanina Ofiteru, Felicia Mihai, Claudia Despan, Silvia Nicoleta Ion   +10 more
doaj   +1 more source

Unraveling The Link Between Lymphopenia And Systemic Lupus Erythematosus: Implications For Disease Severity And Potential Treatment Strategies

Eurasian Journal of Science and Engineering, 2023
Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by chronic inflammation that can potentially impact any body part. Lymphopenia, abnormal low lymphocyte numbers, are frequently observed in individuals with active SLE.
Sawsan S. Al- Rawi, Ahmad H. Ibrahim, Gasheen B. Ahmed   +2 more
doaj   +1 more source

Pooled prevalence of lymphopenia in all-cause hospitalisations and association with infection: a systematic review and meta-analysis

BMC Infectious Diseases, 2023
Background Lymphopenia is defined as a decrease below normal value (often 1.0 x 109 cells/L) of blood circulating lymphocyte count. In the general population, lymphopenia is associated with an increased risk of hospitalisation secondary to infection ...
ZC Elçioğlu, L Errington, B Metes, W Sendama, J Powell, AJ Simpson, AJ Rostron, TP Hellyer   +7 more
doaj   +1 more source