Results 31 to 40 of about 36,827 (260)

Strategies for the Endoscopic Management and Post-Resection Treatment of Superficial Esophageal Squamous Cell Carcinoma [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Endoscopic resection (ER) is preferred for treating superficial esophageal squamous cell carcinoma (SESCC) that has a low risk of lymph node metastasis; the preference is due to the technique’s minimal invasiveness and having outcomes comparable to those
Hyun Ho Choi
doaj   +1 more source

Prognostic Value of the Width of Invasion in pT3 Cutaneous Melanomas

International Journal of Translational Medicine, 2023
Intermediate-thickness melanomas display highly variable outcomes influenced by both clinical and histopathological characteristics. This study investigates several clinicopathological prognostic factors for pT3 cutaneous melanomas, focusing on a novel ...
Dana Antonia Țăpoi, Ancuța-Augustina Gheorghișan-Gălățeanu, Laura Maria Gosman, Adrian Vasile Dumitru, Ana Maria Ciongariu, Mariana Costache   +5 more
doaj   +1 more source

Clinicopathological significance of perineural and lymphovascular invasion in oral and oesophageal squamous cell carcinoma: a retrospective study

Journal of the Pakistan Medical Association
Objective: To determine the presence and association of perineural and lymphovascular invasion with different stages of oral and oesophageal squamous cell carcinoma, and to assess their relationship with lymph node metastasis in both types of tumours.
Anita George, Mahrukh Sheikh, Uzma Bukhari, Syeda Sadia Zafar, Samra Bokhari, Ramsha Azhar   +5 more
doaj   +1 more source

Risk factors for lymph node metastasis in early gastric cancer patients: Report from Eastern Europe country– Lithuania

BMC Surgery, 2017
Background Current risk factors for lymph node metastasis in early gastric cancer have been primarily determined in Asian countries; however their applicability to Western nations is under discussion.
Rimantas Bausys, Augustinas Bausys, Indre Vysniauskaite, Kazimieras Maneikis, Dalius Klimas, Martynas Luksta, Kestutis Strupas, Eugenijus Stratilatovas   +7 more
doaj   +1 more source

F7 Drives Gastric Cancer Metastasis Through Anoikis Resistance and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
ABSTRACT Coagulation factor VII (F7) has been implicated in tumor progression; however, its role in gastric cancer metastasis and immune evasion remains incompletely understood. In this study, we identified F7 as a clinically relevant driver of gastric cancer.
Lei Gao, Qinying Han, Yunpeng Wang, Xuemei Li, Bofang Wang, Baohong Gu, Weidong Li, Lin Xiang, Ying Zhang, Hao Chen   +9 more
wiley   +1 more source

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

Advanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang, Yunfeng Zheng, Chenfan Tian, Yuan Tu, Xiaoxia Chang, Jiaxin Yu, Hangkun Yu, Chunxia Gong, Jie Xiong, Philip N. Baker, Yong Fu, Chao Tong   +11 more
wiley   +1 more source

Prognostic Value of Lymphangiogenesis and Lymphovascular Invasion in Invasive Breast Cancer

Annals of Surgery, 2004
The aim of this study was to investigate the prognostic relevance of lymphangiogenesis and lymphovascular invasion in a large cohort of breast cancer patients.Invasion of tumor cells into blood and lymphatic vessels is one of the critical steps for metastasis.
Sebastian F, Schoppmann, Guenther, Bayer, Klaus, Aumayr, Susanne, Taucher, Silvana, Geleff, Margaretha, Rudas, Ernst, Kubista, Hubert, Hausmaninger, Hellmut, Samonigg, Michael, Gnant, Raimund, Jakesz, Reinhard, Horvat   +11 more
openaire   +3 more sources

Genomic spectra of lymphovascular invasion in breast cancer. [PDF]

Chin J Cancer Res
Lymphovascular invasion (LVI) is a crucial step in metastasis and is closely associated with poor prognosis in patients with breast cancer. However, its clinical and molecular characteristics remain insufficiently defined. We aimed to identify molecular targets for LVI-positive (LVI+) breast cancer and predict patient prognosis via the analysis of ...
Shen C, Lin C, Qu F, Chen C, Shao Z, Jiang Y, Hu X, Di G.   +7 more
europepmc   +3 more sources

Calpastatin is associated with lymphovascular invasion in breast cancer

The Breast, 2011
Metastasis of breast cancer is a major contributor to mortality. Histological assessment of vascular invasion (VI) provides important prognostic information and demonstrates that VI occurs predominantly via lymphatics in breast cancer. We sought to examine genes and proteins involved in lymphovascular invasion (LVI) to understand the mechanisms of this
Sarah J, Storr, Rabab A A, Mohammed, Caroline M, Woolston, Andrew R, Green, Tim, Parr, Inmaculada, Spiteri, Carlos, Caldas, Graham R, Ball, Ian O, Ellis, Stewart G, Martin   +9 more
openaire   +2 more sources

Safe Omission of Postoperative Neck Irradiation in Selected pN0 Patients With Locally Advanced Oral Cavity Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Postoperative radiotherapy is the standard treatment for locally advanced oral squamous cell carcinoma (OSCC); however, the indication for neck irradiation (NI) in pN0 patients remains debatable. We evaluated whether the omission of NI compromises outcomes in pT3–T4 pN0 patients treated with adequate neck dissection (ND).
Mathilde Mirallié, Anouchka Modesto, Marie Pajiep, Sébastien Vergez, Jérôme Sarini, Lucie Piram, Céline Dalmasso, Benjamin Vairel, Emilien Chabrillac, Agnès Dupret‐Bories   +9 more
wiley   +1 more source