Results 161 to 170 of about 609,507 (300)

Lysine-241 has a role in coupling 2OG turnover with substrate oxidation during KDM4-catalysed histone demethylation

, 2018
The JmjC histone demethylases (KDMs) play important roles in modulating histone methylation states and have the potential to be regulated by oxygen availability. Lys‐241 of the KDM4 subfamily is proposed to be important in oxygen binding by KDM4A.
E Flashman (7799900), A Kawamura (7747037), M Abboud (7799894), R Hancock (7799891), C Schofield (7799903), Richard Hopkinson (1267620), T Smart (7799897)   +6 more
core  

Author Correction: KDM6B/Pdk1 glycolytic pathway-driven ZEB2 lactylation promotes cellular cementum formation. [PDF]

Int J Oral Sci
Yang Z, Wang H, Xiao J, Yang Q, Sun J, Liu H, Huang Z, Ma L, Huang X, Wang C, Wang X, Cao Z.   +11 more
europepmc   +1 more source

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

Advanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang, Chunhua Ren, Zhou Qin, Yimeng Cui, Bingbing Zhang, Peng Luo, Xuan Wang, Yaoqi Xie, Xin Zhang, Aifen Yan, Yang Zhang, Dingding Fan, Yang Liu, Wenjie Pan, Xiao Jiang, Lihong Yuan, Haipeng Qin, David M. Irwin, Chaoqun Hu, Yang Liu, Ting Chen   +20 more
wiley   +1 more source

Dynamic global acetylation remodeling during the yeast heat shock response. [PDF]

Genome Biol
Hardman-Kavanaugh RE, Storey AJ, Stuecker TN, Hood SE, Barrett-Wilt GA, Krishnamurthi VR, Wang Y, Byrum SD, Mackintosh SG, Edmondson RD, Wahls WP, Tackett AJ, Lewis JA.   +12 more
europepmc   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

Effect of ruminally protected lysine on growth and nitrogen balance of grain-finished beef cattle fed diets of decreasing protein concentration. [PDF]

Transl Anim Sci
Herzog DS, Jo J, Nakajima D, Nakagawa K, Torres RNS, Nolasco LJ, Schoonmaker JP.   +6 more
europepmc   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

Adaptation of White Adipocytes to Cooler Temperatures: Impacts on Energy Metabolism and Protein Acetylation. [PDF]

FASEB J
Mori H, Hariri H, Moe W, Durham S, Guzman Y, Paulsson E, Simmermon RC, Bhanderi PB, Peterson SK, Dickson MJ, Evans CR, MacDougald OA.   +11 more
europepmc   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Quantitative dietary lysine requirement for juvenile Sebastes schlegeli

, 2006
A 8-week growth trial was conducted to determine the quantitative dietary lysine requirement for juvenile Sebastes schlegeli Semipurified diets were formulated to be isonitrogenous and isoenergetic (48.50% crude protein and 18.04kJ/g gross energy ...
Lei Wu, Xie Shou-Qi (sqxie@ihb.ac.cn), Yan Quan-Gen, Yang Yun-Xia, Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China, Zhu Xiao-Ming   +5 more
core