Results 191 to 200 of about 416,272 (263)

Lysine Triggers Acute Oviposition by Activating the 20E-ETH-JH Signaling Cascade in <i>Drosophila melanogaster</i>. [PDF]

Int J Mol Sci
Yu S, Zhou G, Wang X, Zhang L, Li P.
europepmc   +1 more source

Larvae of the Solitary Bee Epicharis bicolor Are a Rich Source of Yeasts, Including Four Novel Species of the Genera Starmerella, Wickerhamiella and Zygoascus

Yeast, EarlyView.
Four novel yeast species are described associated with larvae of the ground‐nesting solitary bee Epicharis bicolor in Brazil. These yeasts are described based on sequencing of the ITS‐5.8S region and D1/D2 domains of the large subunit of the rRNA gene and phylogenomic analyses.
Ana Raquel O. Santos, Ana Pontes, Katharina O. Barros, Daniela de Laet Souza, Glória R. Franco, Reisla Oliveira, Clemens Schlindwein, Paula Gonçalves, Carla Gonçalves, Marizeth Groenewald, José Paulo Sampaio, Marc‐André Lachance, Carlos A. Rosa   +12 more
wiley   +1 more source

Serum metabolic signatures of nutritional status in early childhood: results from the Brazilian National Survey on Child Nutrition (ENANI-2019). [PDF]

Eur J Nutr
da Silva Rosa Freire S, Nahuel Keller V, Normando P, Machado Schincaglia R, Freitas-Costa NC, Rugani Ribeiro de Castro I, Kroezen Z, Shanmuganathan M, Britz-McKibbin P, Kac G.   +9 more
europepmc   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Safety and efficacy of a feed additive consisting of zinc-lysinate sulfate for all animal species (Phytobiotics Futterzusatzstoffe GmbH). [PDF]

EFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A, Prieto-Maradona M, Theodoridou K, Gropp J, Holczknecht O, Galobart J, Gkimprixi E, Ortuño J, Pizzo F, Tarrès J, Vettori MV, Navarro-Villa A.   +24 more
europepmc   +1 more source

Brain metastasis‐associated fibroblasts shape the tumour microenvironment to enhance cancer cell invasion

Brain Pathology, EarlyView.
Brain metastasis‐associated fibroblasts are active stromal components of the metastatic niche characterised by extracellular matrix remodelling and production of pro‐migratory mediators. They promote monocyte and cancer cell migration and enhance cancer cell invasion while having no growth‐promoting effect on cancer cells.
Barbora Výmolová, Lucie Pfeiferová, Tadeáš Karel Smetana, Petr Výmola, Nikola Ternerová, Michal Zubaľ, Michal Kolář, Jana Šáchová, Soňa Gyönyörová, Eva Balážiová, Magdalena Houdová Megová, Jakub Červenka, Helena Kupcová Skalníková, Michal Španko, Karel Smetana Jr., Lukáš Lacina, David Netuka, Robert Tomáš, Petr Bušek, Aleksi Šedo   +19 more
wiley   +1 more source

An assessment of the cytochrome P450 2-hydroxyisoflavanone synthase (2-HIS) crystal structure. [PDF]

Commun Biol
Poulos TL.
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Modifications of Lysine Residues 294 and 311 Within the Microtubule-Binding Region Alter Tau Aggregation and Tubulin Binding Equilibria. [PDF]

Angew Chem Int Ed Engl
Vogl DP, Migotti M, Konrat R, Conibear AC, Becker CFW.   +4 more
europepmc   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source