Results 101 to 110 of about 1,236,497 (367)
Lytic and mechanical stability of clots composed of fibrin and blood vessel wall components. [PDF]
, 2013 Background Proteases expressed in atherosclerotic plaque lesions generate collagen fragments, release glycosaminoglycans (chondroitin sulfate [CS] and dermatan sulfate [DS]) and expose extracellular matrix (ECM) proteins (e.g.
Bóta, Attila +7 more
core +1 more source
Molecular Oncology, EarlyView.Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou +11 more
wiley +1 more source
Microorganisms, 2020 Interest in preventive or therapeutic strategies targeting gut microbiota is increasing. Such strategies may involve the direct replenishment of the gut microbiota with single strains or strain mixtures, or the manipulation of strain abundance through ...
Mathilde Lebas +4 more
doaj +1 more source
Stochastic modeling of hyposmotic lysis and characterization of different osmotic stability subgroups of human erythrocytes [PDF]
arXiv, 2019 This study proposes a novel stochastic model for the study of hyposmotic hemolysis. This model is capable of reproducing both the kinetics in the transient phase and the lysis equilibrium in the stationary phase, as well as the variability of the experimental measurements.
arxiv
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
BiologyFire blight, caused by the plant-pathogenic bacterium Erwinia amylovora, is a highly contagious and difficult-to-control disease due to its efficient dissemination and survival and the scarcity of effective control methods. Copper and antibiotics are the
Elena G. Biosca +6 more
doaj +1 more source
An attempt to improve the results of treatment for breast cancer complicated by lysis
Опухоли женской репродуктивной системы, 2014 Lysis in locally advanced breast cancer (BC) is not a sign of tumor process dissemination. The correct elaboration of management tactics for such patients may achieve rather good early and late results. The doxorubicin + xeloda regimen for BC complicated
G. A. Khakimov +3 more
doaj +1 more source
Statistical Inference for Stochastic Differential Equations with Memory [PDF]
arXiv, 2013 In this paper we construct a framework for doing statistical inference for discretely observed stochastic differential equations (SDEs) where the driving noise has 'memory'. Classical SDE models for inference assume the driving noise to be Brownian motion, or "white noise", thus implying a Markov assumption.
arxiv
DNA looping provides stability and robustness to the bacteriophage lambda switch [PDF]
, 2009 The bistable gene regulatory switch controlling the transition from lysogeny to lysis in bacteriophage lambda presents a unique challenge to quantitative modeling. Despite extensive characterization of this regulatory network, the origin of the extreme stability of the lysogenic state remains unclear.
arxiv +1 more source
Minimizing technical variation during sample preparation prior to label-free quantitative mass spectrometry [PDF]
, 2015 Sample preparation is the crucial starting point to obtain high-quality mass spectrometry data and can be divided into two main steps in a bottom-up proteomics approach: cell/tissue lysis with or without detergents and a(n) (in-solution) digest ...
De Sutter, Petra +6 more
core +2 more sources