Results 81 to 90 of about 864,381 (312)

A Mutant Isoform of ObgE Causes Cell Death by Interfering with Cell Division

open access: yesFrontiers in Microbiology, 2017
Cell division is a vital part of the cell cycle that is fundamental to all life. Despite decades of intense investigation, this process is still incompletely understood.
Liselot Dewachter   +13 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

BridgesLabCMU/Lysis-sensing-scripts: Paper scripts

open access: yes
<p>Sample scripts for analyzing brightfield timelapses for the manuscript "Cell-lysis sensing drives biofilm formation in <em>Vibrio cholerae</em>"</p ...
Jojo Prentice
core   +1 more source

Lysis of a Single Cyanobacterium for Whole Genome Amplification

open access: yesMicromachines, 2013
Bacterial species from natural environments, exhibiting a great degree of genetic diversity that has yet to be characterized, pose a specific challenge to whole genome amplification (WGA) from single cells. A major challenge is establishing an effective,
Richard N. Zare   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Cell Lysis via Surface Acoustic Waves (SAW)

open access: yes
At the laboratory scale, chemical lysis is the most commonly used method for cell disruption due to its high efficiency, low cost, and compatibility with analytical techniques like PCR and electrophoresis. However, chemical lysis has drawbacks related to
Almanza Alvarez, Gonzalo
core   +1 more source

Imaging the cellular response to transient shear stress using time-resolved digital holography

open access: yes, 2014
Shear stress has been recognized as one of the biophysical methods by which to permeabilize plasma membranes of cells. In particular, high pressure transient hydrodynamic flows created by laser-induced cavitation have been shown to lead to the uptake of ...
Arita, Yoshihiko   +7 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Maximum dose lysis:

open access: yes, 2015
Representative experiments showing clot lysis with fluorescein-labeled plasma clots by tPA (A) and M5 (B) using the three highest doses up to the point at which no further shortening of the lysis time could be achieved.
Victor Gurewich (213767)   +2 more
core   +1 more source

lysis

open access: yes
Citation: 'lysis' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09658 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage of
  +4 more sources

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