Results 71 to 80 of about 831,196 (263)

A novel sulfur‐containing photoinitiator based on benzophenone derivatives for rapid photopolymerization

Smart Molecules
In this study, a series of benzophenone (BP)‐based photoinitiators (PIs), designated as BP‐Sn, were synthesized by the integration of small molecule hydrogen donors into the BP scaffold.
Yu Li, Wenzheng Li, Saihe Yang, Lu Li, Shikun Song, Yuting Tang, Han Han, Zhenyue Duan, Yangyang Xin, Jiangli Fan, Pengzhong Chen, Xiaojun Peng   +11 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Does Water Irrigation Control Pleomorphic Adenoma Cell Growth Better Than Saline?

OTO Open
Objective Sterile water irrigation is anecdotally noted as a method to lyse pleomorphic adenoma (PA) cells in the surgical bed and reduce the rate of recurrence if the tumor is ruptured.
Nathaniel Neptune, Anuhya Kanchibhatla, Kelly R. Magliocca, Brianna Brammer, Brendan L. C. Kinney, Vikash Kansal, Brian J. Boyce, H. Michael Baddour, Nicole C. Schmitt   +8 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Viral Regulation on Bacterial Community Impacted by Lysis-Lysogeny Switch: A Microcosm Experiment in Eutrophic Coastal Waters

Frontiers in Microbiology, 2019
Marine viruses are major drivers of global biogeochemical cycles and energy fluxes, yet the importance of viral impacts on the succession and diversity of the bacterial community remains largely unexplored.
Xiaowei Chen, Ruijie Ma, Yunlan Yang, Yunlan Yang, Nianzhi Jiao, Rui Zhang   +5 more
doaj   +1 more source

Lysis from without [PDF]

Bacteriophage, 2011
In this commentary I consider use of the term "lysis from without" (LO) along with the phenomenon's biological relevance. LO originally described an early bacterial lysis induced by high-multiplicity virion adsorption and that occurs without phage production (here indicated as LO(V)).
openaire   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

lysis

Citation: 'lysis' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09658 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage of
  +4 more sources

Phalangeal and metatarsal bone destruction by subungual squamous cell carcinoma complicated by Peptostreptococcus sp. infection in a dog – importance of histopathological diagnosis.

Medicina Veterinária, 2019
The present article reports the case and complications of a canine with a subungual squamous cell carcinoma infected with Peptostreptococcus sp.
Camila Barbosa Amaral, Mário Antônio Pinto Romão, Ana Maria Reis Ferreira   +2 more
doaj