Results 101 to 110 of about 864,381 (312)
Immunoprecipitation Lysis Buffer v1
This lysis buffer is strong enough for lysis most cell lines and wild enough to keep protein interactions. It has been tested on mouse embryonic stem cells, cancer cell lines and overexpressed cells.
Vivian Liu
core +1 more source
Raw data from the cell lysis evaluation in Fig 2 (see Methods section for more details). (XLSX)
Mara Baldry (843609) +14 more
core +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Genomewide Patterns of Substitution in Adaptively Evolving Populations of the RNA Bacteriophage MS2 [PDF]
Experimental evolution of bacteriophage provides a powerful means of studying the genetics of adaptation, as every substitution contributing to adaptation can be identified and characterized.
Charlesworth, Brian +1 more
core +1 more source
Raw data from the cell lysis evaluation in S6 Fig (see Methods section for more details). (XLSX)
Mara Baldry (843609) +14 more
core +1 more source
In this commentary I consider use of the term "lysis from without" (LO) along with the phenomenon's biological relevance. LO originally described an early bacterial lysis induced by high-multiplicity virion adsorption and that occurs without phage production (here indicated as LO(V)).
openaire +2 more sources
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Rapid cell lysis and DNA capture in a lysis microreactor
In clinical diagnostics, the detection and identification of bacterial organisms based on the analysis of their nucleic acids require cell lysis and DNA extraction from clinical samples.
Viljoen, Hendrik +4 more
core +1 more source
Raw data from the induced cell lysis evaluation in Fig 3 (see Methods section for more details). (XLSX)
Mara Baldry (843609) +14 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source

