Results 41 to 50 of about 864,381 (312)

Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by D94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis [PDF]

open access: yes, 1998
Human histocompatibility leukocyte antigen (HLA)-E is a nonclassical HLA class I molecule, the gene for which is transcribed in most tissues. It has recently been reported that this molecule binds peptides derived from the signal sequence of HLA class I ...
John E. Coligan   +14 more
core   +1 more source

Nanoparticle Lysis of Cryptosporidium Oocysts

open access: yesMethods and Protocols
The extraction of DNA from Cryptosporidium oocysts is challenging due to the robust oocyst wall. Nanoparticles have been applied to disinfect Cryptosporidium oocysts; here, we demonstrate the utilisation of nanoparticles to disrupt the oocyst wall to ...
Ameya Vaidya   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Characterization and Application of a Lytic Phage D10 against Multidrug-Resistant Salmonella

open access: yesViruses, 2021
Salmonella is a widely distributed foodborne pathogen that is a serious threat to human health. The accelerated development of drug resistance and the increased demand for natural foods invoke new biocontrol agents to limit contamination by multidrug ...
Zhiwei Li   +7 more
doaj   +1 more source

Tumor Lysis Syndrome [PDF]

open access: yesArchives of Pathology & Laboratory Medicine, 2018
Tumor lysis syndrome (TLS) is an acute, life-threatening disease among adults and children that is associated with the initiation of cytoreductive therapy in the treatment of malignancy. A pattern of metabolic derangements occurs as a result of a massive release of intracellular contents into the systemic circulation.
Shelly M, Williams, Anthony A, Killeen
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Effectiveness of Laser Suture Lysis After Trabeculectomy with High Early-Postoperative Intraocular Pressure

open access: yes, 2013
Pur po se: To evaluate the effectiveness of laser suture lysis in patients with high intraocular pressure (IOP) after trabeculectomy. Ma te ri al and Met hod: We evaluated retrospectively 22 eyes of 22 patients who had undergone trabeculectomy followed ...
Çiğdem Altan   +6 more
core   +1 more source

Dissolved organic matter and microbial carbon of Protocalcic Chernozems of different land management

open access: yesБюллетень Почвенного института им. В.В. Докучаева, 2022
Water-extractable organic matter is the most active and mobile form of soil carbon. The other active fraction and extremely biolabile is the carbon constituent of microorganisms.
V. A. Kholodov   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Role of hypothetical protein PA1-LRP in antibacterial activity of endolysin from a new Pantoea phage PA1

open access: yesFrontiers in Microbiology
IntroductionPantoea ananatis has emerged as a significant plant pathogen affecting various crops worldwide, causing substantial economic losses. Bacteriophages and their endolysins offer promising alternatives for controlling bacterial infections ...
Ye Tian   +14 more
doaj   +1 more source

Home - About - Disclaimer - Privacy