Results 21 to 30 of about 658 (136)

Indole-Induced Reversion of Intrinsic Multiantibiotic Resistance in Lysobacter enzymogenes. [PDF]

Appl Environ Microbiol, 2017
ABSTRACT Lysobacter species are a group of environmental bacteria that are emerging as a new source of antibiotics. One characteristic of Lysobacter is intrinsic resistance to multiple antibiotics, which had not been studied.
Han Y, Wang Y, Yu Y, Chen H, Shen Y, Du L.   +5 more
europepmc   +4 more sources

Lysobacter enzymogenes: A fully armed biocontrol warrior

Journal of Integrative Agriculture
Lysobacter enzymogenes is less-studied, but emerging as a powerful biocontrol bacterium producing multiple antimicrobial weapons including lytic enzymes, toxins, secondary metabolites and protein secretion systems. The loss of surface-attached flagellum,
Long Lin, Xiaolong Shao, Yicheng Yang, Aprodisia Kavutu Murero, Limin Wang, Gaoge Xu, Yangyang Zhao, Sen Han, Zhenhe Su, Kangwen Xu, Mingming Yang, Jinxing Liao, Kaihuai Li, Fengquan Liu, Guoliang Qian   +14 more
doaj   +3 more sources

Identification of atypical T4SS effector proteins mediating bacterial defense

mLife, 2023
To remain competitive, proteobacteria use various contact‐dependent weapon systems to defend against microbial competitors. The bacterial‐killing type IV secretion system (T4SS) is one such powerful weapon.
Xi Shen, Zixiang Yang, Zihan Li, Dan Xiong, Jinxing Liao, Weimei He, Danyu Shen, Xiaolong Shao, Ben Niu, Yongxing He, Yong‐Gui Gao, Guoliang Qian   +11 more
doaj   +2 more sources

Systematic optimization for production of the anti‐MRSA antibiotics WAP‐8294A in an engineered strain of Lysobacter enzymogenes [PDF]

Microbial Biotechnology, 2019
Summary WAP‐8294A is a group of cyclic lipodepsipeptides and considered as the first‐in‐class new chemical entity with potent activity against methicillin‐resistant Staphylococcus aureus.
Xusheng Chen, Shanren Li, Lingjun Yu, Amanda Miller, Liangcheng Du   +4 more
doaj   +2 more sources

Biosynthesis of the Polycyclic System in the Antifungal HSAF and Analogues from Lysobacter enzymogenes. [PDF]

Angew Chem Int Ed Engl, 2018
AbstractThe biocontrol agent Lysobacter enzymogenes produces polycyclic tetramate macrolactams (PoTeMs), including the antifungal HSAF. To elucidate the biosynthesis of the cyclic systems, we identified eleven HSAF precursors/analogues with zero, one, two, or three rings through heterologous expression of the HSAF gene cluster.
Li Y, Wang H, Liu Y, Jiao Y, Li S, Shen Y, Du L.   +6 more
europepmc   +5 more sources

Mechanism of Lysobacter enzymogenes resistance toward fungi induced by fungal-derived signal α-terpinene [PDF]

Applied and Environmental Microbiology
Bacterial-fungal interactions (BFI) are critical drivers of ecosystem functions, and their molecular mechanisms remain incompletely understood. Chemical signals are crucial mediators of microbial communication, but the signaling mechanisms of terpene ...
Meixue Zhu, Yuying Li, Fang Nan, Jia Wang, Benfeng Gao, Huihui Song, Zeran Bian, Xuejie Wang, Yuxiang Zhu, Yan Wang   +9 more
doaj   +2 more sources

LeTetR Positively Regulates 3-Hydroxylation of the Antifungal HSAF and Its Analogs in Lysobacter enzymogenes OH11 [PDF]

Molecules, 2020
The biocontrol agent Lysobacter enzymogenes OH11 produces several structurally distinct antibiotic compounds, including the antifungal HSAF (Heat Stable Antifungal Factor) and alteramides, along with their 3-dehydroxyl precursors (3-deOH).
Lingjun Yu, Vimmy Khetrapal, Fengquan Liu, Liangcheng Du   +3 more
doaj   +2 more sources

Identification of Pyrrole-2-Carboxylic Acid from the Biocontrol Agent Lysobacter Involved in Interactions with Fusarial Fungi [PDF]

Microorganisms
Lysobacter, a genus of Gram-negative bacteria, is known for producing antibiotic compounds, making it a promising biocontrol agent against crop pathogens.
Vishakha Jayasekera, Yong Han, Liangcheng Du   +2 more
doaj   +2 more sources

Characterization of a bacterial strain T226 and its efficacy in controlling post-harvest citrus anthracnose [PDF]

Frontiers in Microbiology
Postharvest anthracnose of citrus, caused by the fungus Colletotrichum gloeosporioides, leads to significant economic losses. There is a growing need for effective biological control agents to manage this disease. In this study, a bacterial strain (T226)
Qian Wang, Juan Song, Quan Zeng, Xuelian Ye, Guoying Shi, Chunjin Hu   +5 more
doaj   +2 more sources

LesR is a novel upstream regulator that controls downstream Clp expression to modulate antibiotic HSAF biosynthesis and cell aggregation in Lysobacter enzymogenes OH11 [PDF]

Microbial Cell Factories, 2017
Background Heat-stable antifungal factor (HSAF) is a polycyclic tetramate macrolactam secondary metabolite that exhibits broad-spectrum inhibitory activities against filamentous fungal pathogens. The native yield of this chemical is low.
Huiyong Xu, Ruping Wang, Yangyang Zhao, Zheng Qing Fu, Guoliang Qian, Fengquan Liu   +5 more
doaj   +2 more sources