Vesicular Delivery of the Antifungal Antibiotics of Lysobacter enzymogenes C3. [PDF]
Abstract Lysobacter enzymogenes C3 is a predatory strain of gram-negative gliding bacteria that produces antifungal antibiotics by the polyketide synthetic pathway. Outer membrane vesicles (OMV) are formed as a stress response and can deliver virulence factors to host cells.
Meers PR +11 more
europepmc +4 more sources
Hijacking competitor-derived signals: RcsB/C drives Lysobacter enzymogenes to exploit farnesol for enhanced antifungal capacity [PDF]
Microbial antagonism is a fundamental ecological process that shapes community composition and maintains ecosystem balance. However, the molecular signals, such as cross-kingdom interactions between bacteria and fungi in natural environments, remain ...
Fang Nan +7 more
doaj +2 more sources
Background Powdery mildew is a common leaf disease of crops worldwide. A large quantity of chemical fungicides is used to control this disease in horticulture and agriculture, producing serious safety and environmental problems.
Hongjun Yang +4 more
doaj +2 more sources
Separation of Heat-Stable Antifungal Factor From Lysobacter enzymogenes Fermentation Broth via Photodegradation and Macroporous Resin Adsorption [PDF]
Heat-stable antifungal factor (HSAF) is produced by the fermentation of Lysobacter enzymogenes, which is known for its broad-spectrum antifungal activity and novel mode of action.
Bao Tang +8 more
doaj +2 more sources
Interspecies and Intraspecies Signals Synergistically Regulate Lysobacter enzymogenes Twitching Motility. [PDF]
The mechanism underlying bacterial twitching motility is an important research area because it is closely related to social and pathogenic behaviors. The mechanism mediating cell-to-cell perception of twitching motility is largely unknown.
Feng T +9 more
europepmc +4 more sources
The indiscriminate use of chemical fertilizers has led to adverse environmental impacts and poor crop quality and accelerates the depletion of mineral reserves used for fertilizer production.
Danmei Chen +3 more
doaj +2 more sources
Systematic optimization for production of the anti‐MRSA antibiotics WAP‐8294A in an engineered strain of Lysobacter enzymogenes [PDF]
Summary WAP‐8294A is a group of cyclic lipodepsipeptides and considered as the first‐in‐class new chemical entity with potent activity against methicillin‐resistant Staphylococcus aureus.
Xusheng Chen +4 more
doaj +2 more sources
Identification of atypical T4SS effector proteins mediating bacterial defense
To remain competitive, proteobacteria use various contact‐dependent weapon systems to defend against microbial competitors. The bacterial‐killing type IV secretion system (T4SS) is one such powerful weapon.
Xi Shen +11 more
doaj +2 more sources
Biosynthesis of the Polycyclic System in the Antifungal HSAF and Analogues from Lysobacter enzymogenes. [PDF]
AbstractThe biocontrol agent Lysobacter enzymogenes produces polycyclic tetramate macrolactams (PoTeMs), including the antifungal HSAF. To elucidate the biosynthesis of the cyclic systems, we identified eleven HSAF precursors/analogues with zero, one, two, or three rings through heterologous expression of the HSAF gene cluster.
Li Y +6 more
europepmc +5 more sources
LeTetR Positively Regulates 3-Hydroxylation of the Antifungal HSAF and Its Analogs in Lysobacter enzymogenes OH11 [PDF]
The biocontrol agent Lysobacter enzymogenes OH11 produces several structurally distinct antibiotic compounds, including the antifungal HSAF (Heat Stable Antifungal Factor) and alteramides, along with their 3-dehydroxyl precursors (3-deOH).
Lingjun Yu +3 more
doaj +2 more sources

