Results 101 to 110 of about 8,797 (254)

Isolation and Characterization of Novel Mycobacteriophages From the Central Illinois Region [PDF]

, 2013
Members of the Illinois Wesleyan General Biology Science Education Alliance (SEA) laboratory isolated and characterized fifteen distinctive phages capable of infecting Mycobacterium smegmatis. Each student collected soil samples from the central Illinois
Aron, Rachel, Beehler, Blake, Ende, Rachel, Garthe, Logan, Joiner, Netherland, Kelley, Tess, Killough, Lauren, Kozdronkiewicz, Michal, Kraut, Jessica, Lang, Jennifer, Piotrowiak, Matthew, Ramachandran, Prartana, Walker, Faculty Advisor, Loni   +12 more
core   +1 more source

Physiochemically and Genetically Engineered Bacteria: Instructive Design Principles and Diverse Applications

Advanced Science, Volume 11, Issue 30, August 14, 2024.
Engineered bacteria specifically refer to advanced physiochemical or genetic modifications of diagnostic bacteria, which can compensate for the shortcomings of natural strains. After engineering, these diagnostic bacteria are encouraged to lyse tumors, regulate immunity and cellular communication such immune cells, influence metabolic pathways ...
Xia Lin, Rong Jiao, Haowen Cui, Xuebing Yan, Kun Zhang   +4 more
wiley   +1 more source

New functions of pirin proteins and a 2‐ketoglutarate: Ferredoxin oxidoreductase ortholog in Bacteroides fragilis metabolism and their impact on antimicrobial susceptibility to metronidazole and amixicile

MicrobiologyOpen, Volume 13, Issue 4, August 2024.
This study reveals that several enzymes involved in the central metabolism of Bacteroides fragilis are regulated by protein‐protein interactions with pirin proteins. We observed changes in susceptibility to the antimicrobials metronidazole and amixicile in various metabolic mutants.
Andrea M. Gough, Anita C. Parker, Patricia J. O'Bryan, Terence R. Whitehead, Sourav Roy, Brandon L. Garcia, Paul S. Hoffman, C. Jeffrey Smith, Edson R. Rocha   +8 more
wiley   +1 more source

Population fitness and the regulation of Escherichia coli genes by bacterial viruses.

PLoS Biology, 2005
Temperate bacteriophage parasitize their host by integrating into the host genome where they provide additional genetic information that confers higher fitness on the host bacterium by protecting it against invasion by other bacteriophage, by increasing ...
Ying Chen, Ido Golding, Satoshi Sawai, Ling Guo, Edward C Cox   +4 more
doaj   +2 more sources

Specific Integration of Temperate Phage Decreases the Pathogenicity of Host Bacteria

Frontiers in Cellular and Infection Microbiology, 2020
Temperate phages are considered as natural vectors for gene transmission among bacteria due to the ability to integrate their genomes into a host chromosome, therefore, affect the fitness and phenotype of host bacteria. Many virulence genes of pathogenic
Yibao Chen, Yibao Chen, Lan Yang, Lan Yang, Dan Yang, Dan Yang, Jiaoyang Song, Jiaoyang Song, Can Wang, Erchao Sun, Erchao Sun, Erchao Sun, Changqin Gu, Huanchun Chen, Huanchun Chen, Yigang Tong, Pan Tao, Pan Tao, Pan Tao, Bin Wu, Bin Wu   +20 more
doaj   +1 more source

Designer Gene Networks: Towards Fundamental Cellular Control

, 2001
The engineered control of cellular function through the design of synthetic genetic networks is becoming plausible. Here we show how a naturally occurring network can be used as a parts list for artificial network design, and how model formulation leads ...
Ackers, Arkin, Barkai, Becksei, Bialek, Bray, Chen, Dickson, Elowitz, Endy, Gardner, Gillespie, Glass, Glass, Glass, Hammond, Harada, Harding, Hartwell, Hasty, Jacob, Johnson, Johnson, Kauffman, Keller, Lauffenburger, Lowman, McAdams, McAdams, McAdams, McClure, Meyer, Monod, Monod, Moran, Novak, Novak, Novick, Ohlendorf, Palsson, Ptaschne, Reinitz, Rozanov, Samoilov, Sancho, Savageau, Savageau, Savageau, Shea, Smolen, Sveiczer, Szafranski, Tyson, Villaverde, von Hippel, Wolf, Wong   +56 more
core   +1 more source

The PDZ domain of the SpoIVB serine peptidase facilitates multiple functions [PDF]

, 2001
During spore formation in Bacillus subtilis, the SpoIVB protein is a critical component of the sigma (K) regulatory checkpoint. SpoIVB has been shown to be a serine peptidase that is synthesized in the spore chamber and which self-cleaves, releasing ...
Beebe K. D., Cutting S., Cutting S., Cutting S., Cutting S., Daniels D. L., Doyle D. A., Gee S. H., Gomez M., Gomez M., Hillier B. J., Keiler K. C., Kraulis P. J., Lewis A. P., Oke V., Pallen M. J., Pallen M. J., Ponting C. P., Ponting C. P., Resnekov O., Resnekov O., Rudner D. Z., Sali A., Sandman K., Schneider S., Schultz J., Songyang Z., Stricker N. L., Tsunoda S., Wakeley P., Wakeley P.   +30 more
core   +3 more sources

Transfer of antibiotic resistance in Staphylococcus aureus [PDF]

, 2017
Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers. Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance genes from other S. aureus strains or even from other genera.
Haaber, Jakob, Ingmer, Hanne, Penadés, José R.   +2 more
core   +1 more source

Genetic and phenotypic diversity in Burkholderia: contributions by prophage and phage-like elements [PDF]

, 2010
Background Burkholderia species exhibit enormous phenotypic diversity, ranging from the nonpathogenic, soil- and water-inhabiting Burkholderia thailandensis to the virulent, host-adapted mammalian pathogen B. mallei.
Catherine M Ronning, Liliana Losada, Lauren Brinkac, Jason Inman, Ricky L Ulrich, Mark Schell, William C Nierman, David DeShazer   +7 more
core   +2 more sources

The prevalence and impact of lysogeny among oral isolates of Enterococcus faecalis

Journal of Oral Microbiology, 2019
Bacterial phenotypic properties are frequently influenced by the uptake of extrachromosomal genetic elements, such as plasmids and bacteriophage genomes.
Roy H. Stevens, Hongming Zhang, Christine Sedgley, Adam Bergman, Anil Reddy Manda   +4 more
doaj   +1 more source