Results 11 to 20 of about 5,681 (197)

Temperate phage-antibiotic synergy is widespread—extending to Pseudomonas—but varies by phage, host strain, and antibiotic pairing [PDF]

mBio
Bacteriophages (phages) are bacterial-specific viruses that can be used alone or with antibiotics to reduce bacterial load. Most phages are unsuitable for therapy because they are “temperate” and can integrate into the host genome, forming a lysogen that
Rabia Fatima, Alexander P. Hynes
doaj   +2 more sources

What makes a temperate phage an effective bacterial weapon? [PDF]

mSystems
Temperate bacteriophages (phages) are common features of bacterial genomes and can act as self-amplifying biological weapons, killing susceptible competitors and thus increasing the fitness of their bacterial hosts (lysogens).
M. J. N. Thomas, M. A. Brockhurst, K. Z. Coyte   +2 more
doaj   +2 more sources

Noncanonical amino acids as prophage inducers for protein regulation in bacteria-based delivery systems [PDF]

mBio
Genetically engineered bacteria represent a promising drug delivery tool for disease treatment. The development of new strategies for specific and independent protein regulation is necessary, especially for combination protein drug therapy.
Hongfang Liu, Sijia Shen, Qi Xu, Yuyang Wang, Kejing Qi, Bowen Lu, Bing Tang, Min Wu, Fei Gan   +8 more
doaj   +2 more sources

Isolation and Characterization of the subcluster L2 Mycobacteriophage Underpass and its lysogen. [PDF]

MicroPubl Biol
Toth KR, Rogers AR, Wenzel ER, Ponnwitz F, Galdo ML, Lacour PM, Torres Cruz JA, Parikh M, Bard Hennessy IB, Duval NK, Rosato RA, Elshayet RM, Joshi D, Zile L, Aquilino JF, Braverman JM, Sunnen CN, Lee-Soety JY.   +17 more
europepmc   +3 more sources

Bacterial resistance to temperate phage is influenced by the frequency of lysogenic establishment [PDF]

iScience
Summary: Temperate phages can shape bacterial community dynamics and evolution through lytic and lysogenic life cycles. In response, bacteria that resist phage infection can emerge.
Hiba Baaziz, Rita Makhlouf, Michael McClelland, Bryan B. Hsu   +3 more
doaj   +2 more sources

Isolation from Lysogens v1

, 2015
This is a protocol from: Stedman,K. M., K. Porter, and M. L. Dyall-Smith. 2010. Chapter 6:The isolation of viruses infecting Archaea.Manual of Aquatic Viral Ecology. Waco, TX:American Society of Limnology and Oceanography. doi:10.4319/mave.2010.978-0-9845591-0-7 Please see the published manuscript for additional information.
Kenneth M. Stedman, not provided Kate Porter, not provided and Mike L. Dyall-Smith   +2 more
openaire   +2 more sources

Mycobacteriophage Mcgavigan Uses Noncanonical Bxb1-Like Repressor for Heterotypic Superinfection Immunity. [PDF]

J Basic Microbiol
ABSTRACT Mycobacteriophage Mcgavigan could be a promising candidate for use as a preventative agent against infections with Mycobacterium avium subsp. paratuberculosis. Bioinformatic analysis of the Mcgavigan genome revealed the presence of an operon containing a “Bxb1‐like” repressor.
Shafer N, Dubrule BE, De Buck J.
europepmc   +2 more sources

Temperate Bacteriophages—The Powerful Indirect Modulators of Eukaryotic Cells and Immune Functions

Viruses, 2021
Bacteriophages are natural biological entities that limit the growth and amplification of bacteria. They are important stimulators of evolutionary variability in bacteria, and currently are considered a weapon against antibiotic resistance of bacteria ...
Martyna Cieślik, Natalia Bagińska, Ewa Jończyk-Matysiak, Alicja Węgrzyn, Grzegorz Węgrzyn, Andrzej Górski   +5 more
doaj   +1 more source

Replication Region Analysis Reveals Non-lambdoid Shiga Toxin Converting Bacteriophages

Frontiers in Microbiology, 2021
Shiga toxin is the major virulence factor of enterohemorrhagic Escherichia coli (EHEC), and the gene encoding it is carried within the genome of Shiga toxin-converting phages (Stx phages).
Ann-Katrin Llarena, Marina Aspholm, Kristin O’Sullivan, Grzegorz Wêgrzyn, Toril Lindbäck   +4 more
doaj   +1 more source

Isolation and Characterization of a Novel Temperate Escherichia coli Bacteriophage, Kapi1, Which Modifies the O-Antigen and Contributes to the Competitiveness of Its Host during Colonization of the Murine Gastrointestinal Tract

mBio, 2022
In this study, we describe the isolation and characterization of novel bacteriophage vB_EcoP_Kapi1 (Kapi1) isolated from a strain of commensal Escherichia coli inhabiting the gastrointestinal tract of healthy mice. We show that Kapi1 is a temperate phage
Kat Pick, Tingting Ju, Benjamin P. Willing, Tracy L. Raivio   +3 more
doaj   +1 more source