Bacterial resistance to temperate phage is influenced by the frequency of lysogenic establishment [PDF]
iScienceSummary: Temperate phages can shape bacterial community dynamics and evolution through lytic and lysogenic life cycles. In response, bacteria that resist phage infection can emerge.
Hiba Baaziz +3 more
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Mycobacteriophage Mcgavigan Uses Noncanonical Bxb1-Like Repressor for Heterotypic Superinfection Immunity. [PDF]
J Basic MicrobiolABSTRACT Mycobacteriophage Mcgavigan could be a promising candidate for use as a preventative agent against infections with Mycobacterium avium subsp. paratuberculosis. Bioinformatic analysis of the Mcgavigan genome revealed the presence of an operon containing a “Bxb1‐like” repressor.
Shafer N, Dubrule BE, De Buck J.
europepmc +2 more sources
A φSa3int (NM3) Prophage Domestication in <i>Staphylococcus aureus</i> Leads to Increased Virulence Through Human Immune Evasion. [PDF]
MedComm (2020)Prophages play a significant role in modulating bacterial virulence and pathogenicity. Our results suggest domestication of φSa3int prophage leads to reduced phagocytosis mediating escape of S. aureus from human innate immunity. As such, targeted identification of mobile genetic elements (MGEs) in addition to species and strain identification may lead ...
Nepal R +9 more
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Temperate Bacteriophages—The Powerful Indirect Modulators of Eukaryotic Cells and Immune Functions
Viruses, 2021 Bacteriophages are natural biological entities that limit the growth and amplification of bacteria. They are important stimulators of evolutionary variability in bacteria, and currently are considered a weapon against antibiotic resistance of bacteria ...
Martyna Cieślik +5 more
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An Efficient, Counter-Selection-Based Method for Prophage Curing in Pseudomonas aeruginosa Strains
Viruses, 2021 Prophages are bacteriophages in the lysogenic state, where the viral genome is inserted within the bacterial chromosome. They contribute to strain genetic variability and can influence bacterial phenotypes. Prophages are highly abundant among the strains
Esther Shmidov +5 more
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Life, 2023 Antimicrobial resistance is rising as a major global public health threat and antibiotic resistance genes are widely spread among species, including human oral pathogens, e.g., Aggregatibacter actinomycetemcomitans.
Gaoyan Grace Tang-Siegel
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Replication Region Analysis Reveals Non-lambdoid Shiga Toxin Converting Bacteriophages
Frontiers in Microbiology, 2021 Shiga toxin is the major virulence factor of enterohemorrhagic Escherichia coli (EHEC), and the gene encoding it is carried within the genome of Shiga toxin-converting phages (Stx phages).
Ann-Katrin Llarena +4 more
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Characterization of prophages in bacterial genomes from the honey bee (Apis mellifera) gut microbiome [PDF]
PeerJ, 2023 The gut of the European honey bee (Apis mellifera) possesses a relatively simple bacterial community, but little is known about its community of prophages (temperate bacteriophages integrated into the bacterial genome).
Emma K. Bueren +5 more
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mBio, 2022 In this study, we describe the isolation and characterization of novel bacteriophage vB_EcoP_Kapi1 (Kapi1) isolated from a strain of commensal Escherichia coli inhabiting the gastrointestinal tract of healthy mice. We show that Kapi1 is a temperate phage
Kat Pick +3 more
doaj +1 more source
From bacterial predators to partners: phages in agriculture. [PDF]
New PhytolSummary Bacteriophages, viruses that infect bacteria, are critical players for shaping the taxonomic and functional composition of plant‐associated microbiomes. Yet, their roles in plant health remain overlooked, along with their implications for sustainable agriculture.
Salehimoghaddam Z, Hynes AP, Doyle RT.
europepmc +2 more sources