Results 61 to 70 of about 5,681 (197)

Pavlovian‐Type Learning in Environmental Bacteria: Regulation of Herbicide Resistance by Arsenic in Pseudomonas putida

Environmental Microbiology, Volume 26, Issue 12, December 2024.
Similar to Pavlov's dog experiment, where two different stimuli can elicit the same response, environmental bacteria exposed to one of two simultaneous and unrelated stimuli may eventually trigger responses to both. ABSTRACT The canonical arsRBC genes of the ars1 operon in Pseudomonas putida KT2440, which confer tolerance to arsenate and arsenite, are ...
David Paez‐Espino, Gonzalo Durante‐Rodríguez, Elena Alonso Fernandes, Manuel Carmona, Victor de Lorenzo   +4 more
wiley   +1 more source

Estimating the Importance of Viral Contributions to Soil Carbon Dynamics

Global Change Biology, Volume 30, Issue 10, October 2024.
Written Summary: Viruses are ubiquitous in soils and impact global carbon cycling through infection of microbial hosts. Using existing data from the literature, we generate a global budget of the carbon potentially released from microbial biomass by viral infections in soils.
Amy E. Zimmerman, Emily B. Graham, Jason McDermott, Kirsten S. Hofmockel   +3 more
wiley   +1 more source

DNA Packaging Specificity in the λ‐Like Phages: Gifsy‐1

Molecular Microbiology, Volume 122, Issue 4, Page 491-503, October 2024.
Dimeric λ TerS and chimera transition points. The N‐termini of each TerS derives from a λ‐like source phage: Gifsy‐1, 21, and N15 (labeled arrows). The N‐terminus includes the winged‐helix‐turn‐helix (HTH) DNA‐binding motif that confers the source phage's DNA packaging specificity.
Michael Feiss, Jean Arens Sippy
wiley   +1 more source

Phages for Phage Therapy: Isolation, Characterization, and Host Range Breadth

Pharmaceuticals, 2019
For a bacteriophage to be useful for phage therapy it must be both isolated from the environment and shown to have certain characteristics beyond just killing strains of the target bacterial pathogen.
Paul Hyman
doaj   +1 more source

Physiochemically and Genetically Engineered Bacteria: Instructive Design Principles and Diverse Applications

Advanced Science, Volume 11, Issue 30, August 14, 2024.
Engineered bacteria specifically refer to advanced physiochemical or genetic modifications of diagnostic bacteria, which can compensate for the shortcomings of natural strains. After engineering, these diagnostic bacteria are encouraged to lyse tumors, regulate immunity and cellular communication such immune cells, influence metabolic pathways ...
Xia Lin, Rong Jiao, Haowen Cui, Xuebing Yan, Kun Zhang   +4 more
wiley   +1 more source

New functions of pirin proteins and a 2‐ketoglutarate: Ferredoxin oxidoreductase ortholog in Bacteroides fragilis metabolism and their impact on antimicrobial susceptibility to metronidazole and amixicile

MicrobiologyOpen, Volume 13, Issue 4, August 2024.
This study reveals that several enzymes involved in the central metabolism of Bacteroides fragilis are regulated by protein‐protein interactions with pirin proteins. We observed changes in susceptibility to the antimicrobials metronidazole and amixicile in various metabolic mutants.
Andrea M. Gough, Anita C. Parker, Patricia J. O'Bryan, Terence R. Whitehead, Sourav Roy, Brandon L. Garcia, Paul S. Hoffman, C. Jeffrey Smith, Edson R. Rocha   +8 more
wiley   +1 more source

Mycobacterium Phage Butters-Encoded Proteins Contribute to Host Defense against Viral Attack

mSystems, 2020
A diverse set of prophage-mediated mechanisms protecting bacterial hosts from infection has been recently uncovered within cluster N mycobacteriophages isolated on the host, Mycobacterium smegmatis mc2155.
Catherine M. Mageeney, Hamidu T. Mohammed, Marta Dies, Samira Anbari, Netta Cudkevich, Yanyan Chen, Javier Buceta, Vassie C. Ware   +7 more
doaj   +1 more source

Phages produce persisters

Microbial Biotechnology, Volume 17, Issue 8, August 2024.
Bacterial infections are predicted to be the main cause of death by 2050, and persister cells often form during periods of lethal stress. Here, we show phage infections generate persister cells, and these persisters may undermine phage therapy. Abstract Arguably, the greatest threat to bacteria is phages.
Laura Fernández‐García, Joy Kirigo, Daniel Huelgas‐Méndez, Michael J. Benedik, María Tomás, Rodolfo García‐Contreras, Thomas K. Wood   +6 more
wiley   +1 more source

Establishing a straightforward I‐SceI‐mediated recombination one‐plasmid system for efficient genome editing in P. putida KT2440

Microbial Biotechnology, Volume 17, Issue 7, July 2024.
In this study, we demonstrate a one‐plasmid genome editing tool, accelerating the engineering cycle from 9 to 3 days. Based on the pEMG backbone, a tightly controllable I‐sceI gene and a constitutive sacB gene were assembled on a single plasmid. The requirement of a second plasmid transformation and a laborious plasmid curing process was circumvented ...
Hao Meng, Sebastian Köbbing, Lars M. Blank   +2 more
wiley   +1 more source

Population fitness and the regulation of Escherichia coli genes by bacterial viruses.

PLoS Biology, 2005
Temperate bacteriophage parasitize their host by integrating into the host genome where they provide additional genetic information that confers higher fitness on the host bacterium by protecting it against invasion by other bacteriophage, by increasing ...
Ying Chen, Ido Golding, Satoshi Sawai, Ling Guo, Edward C Cox   +4 more
doaj   +2 more sources