Results 71 to 80 of about 20,096 (124)

Emerging roles of lysophosphatidic acid receptor subtype 5 (LPAR5) in inflammatory diseases and cancer. [PDF]

Pharmacol Ther, 2023
Dacheux MA, Norman DD, Tigyi GJ, Lee SC.
europepmc   +1 more source

Lysophosphatidic Acid Receptor Signaling in the Human Breast Cancer Tumor Microenvironment Elicits Receptor-Dependent Effects on Tumor Progression. [PDF]

Int J Mol Sci, 2023
Benesch MGK, Wu R, Tang X, Brindley DN, Ishikawa T, Takabe K.   +5 more
europepmc   +1 more source

Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model. [PDF]

Proc Natl Acad Sci U S A, 2022
Axelsson Raja A, Wakimoto H, DeLaughter DM, Reichart D, Gorham J, Conner DA, Lun M, Probst CK, Sakai N, Knipe RS, Montesi SB, Shea B, Adam LP, Leinwand LA, Wan W, Choi ES, Lindberg EL, Patone G, Noseda M, Hübner N, Seidman CE, Tager AM, Seidman JG, Ho CY.   +23 more
europepmc   +1 more source

Gintonin Binds to Reduced LPA4 Receptor Subtype in Human Cortical Neurons in Alzheimer’s Disease Brains

Biomolecules
Ginseng, a traditional herbal medicine with a long history of use, is known to support human health, particularly by influencing brain function. Recent studies have identified gintonin, a lysophosphatidic acid (LPA) receptor ligand derived from ginseng ...
Kyu-Sung Kim, Rami Lee, Inyeong Park, Sung-Hee Hwang, Yeshin Kim, Jae-Won Jang, Hyung-Seok Kim, Seong-Min Choi, Sang Jin Kim, Hwa Jin Cho, Ik-Hyun Cho, Jong-Hoon Kim, Do-Geun Kim, Seung-Yeol Nah   +13 more
doaj   +1 more source

Structure of the active G_i-coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. [PDF]

Nat Commun, 2022
Akasaka H, Tanaka T, Sano FK, Matsuzaki Y, Shihoya W, Nureki O.   +5 more
europepmc   +1 more source

An Update on Sphingosine-1-Phosphate and Lysophosphatidic Acid Receptor Transcripts in Rodent Olfactory Mucosa. [PDF]

Int J Mol Sci, 2022
Toebbe JT, Genter MB.
europepmc   +1 more source

Molecular Regulation of Lysophosphatidic Acid Receptor 1 Maturation and Desensitization. [PDF]

Cell Biochem Biophys, 2021
Zhao J, Stephens T, Zhao Y.
europepmc   +1 more source

Isoquinolone derivatives as lysophosphatidic acid receptor 5 (LPA5) antagonists: Investigation of structure-activity relationships, ADME properties and analgesic effects. [PDF]

Eur J Med Chem, 2022
Zhang D, Decker AM, Woodhouse K, Snyder R, Patel P, Harris DL, Tao YX, Li JX, Zhang Y.   +8 more
europepmc   +1 more source

Lysophosphatidic Acid Receptor 6 (LPAR6) Is a Potential Biomarker Associated with Lung Adenocarcinoma. [PDF]

Int J Environ Res Public Health, 2021
He J, Gao R, Meng M, Yu M, Liu C, Li J, Song Y, Wang H.   +7 more
europepmc   +1 more source

Inhibition of lysophosphatidic acid receptor 1 relieves PMN recruitment in CNS via LPA1/TSP1/CXCR2 pathway and alleviates disruption on blood-brain barrier following intracerebral haemorrhage in mice. [PDF]

Fluids Barriers CNS, 2023
Gao L, Peng L, Sherchan P, Tang H, Liu Y, Xiao J, Shi H, Luo Y, Tang J, Zhang JH, Xia Y.   +10 more
europepmc   +1 more source