Results 91 to 100 of about 32,338 (252)

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Non-Targeted Metabolomics Reveal Apomorphine’s Therapeutic Effects and Lysophospholipid Alterations in Steatohepatitis

Antioxidants
Metabolic dysfunction-associated steatohepatitis (MASH), characterized by progressive inflammation and fibrosis, evolves from metabolic dysfunction-associated steatotic liver disease and significantly heightens the risk of cirrhosis and hepatocellular ...
Hideo Ogiso, Kouichi Miura, Ryozo Nagai, Hitoshi Osaka, Kenichi Aizawa   +4 more
doaj   +1 more source

Loss of G2A promotes macrophage accumulation in atherosclerotic lesions of low density lipoprotein receptor-deficient mice

Journal of Lipid Research, 2005
Lysophosphatidylcholine (LPC) is considered a major proatherogenic component of oxidized low density lipoprotein based on its proinflammatory actions in vitro. LPC stimulates macrophage and T-cell chemotaxis via the G protein-coupled receptor G2A and may
Brian W. Parks, Ginger P. Gambill, Aldons J. Lusis, Janusz H.S. Kabarowski   +3 more
doaj   +1 more source

Lysophosphatidylcholine and sodium-calcium exchange in cardiac sarcolemma: comparison with ischemia

, 1991
Lysophosphoglyceride accumulation in ischemic myocardium has been hypothesized to be a mechanism for altered sarcolemmal properties that underlie electrophysiological changes and Ca2+ accumulation in ischemia.
M. M. Bersohn, K. D. Philipson, R. S. Weiss   +2 more
core   +1 more source

Metabolic pattern across energy imbalance: An exploratory metabolomics study of female body weight extremes including anorexia nervosa and athletes

Experimental Physiology, EarlyView.
Abstract In anorexia nervosa (AN), prolonged metabolic adaptation to severe energy deficiency can impair treatment efficacy. Similarly, low energy availability poses a recognized risk to athletes, potentially compromising health and performance. This cross‐sectional study aimed to characterize the plasma metabolic pattern of females with varying ...
Sonja Lackner, Olli Kärkkäinen, Sabrina Mörkl, Wolfram Müller, Alfred Fürhapter‐Rieger, Kati Hanhineva, Sandra Johanna Holasek   +6 more
wiley   +1 more source

Dietary phospholipid carriers of DHA do not increase brain DHA levels: a replication study

Journal of Lipid Research
DHA is primarily found in fish and seafood as triacylglycerols and phospholipids (PLs). Oral administration of PL DHA forms, sn-1 lysophosphatidylcholine-DHA (sn-1 LPC-DHA) and di-DHA phosphatidylcholine (di-DHA-PC), has been suggested to increase brain ...
Brinley J. Klievik, Yan Fu, Aidan D. Tyrrell, Chuck T. Chen, Adam H. Metherel, Richard P. Bazinet   +5 more
doaj   +1 more source

Exchange of phospholipid classes between liver microsomes and plasma: comparison of rat, rabbit, and guinea pig

Journal of Lipid Research, 1971
Rat and guinea pig liver microsomes labeled with phospholipid 32P were incubated with rat, guinea pig, and rabbit plasma in a KC1–Tris–EDTA buffer. A net transfer of microsomal phosphatidylcholine and phosphatidylethanolamine to plasma was observed.
D.B. ZILVERSMIT
doaj   +1 more source

Acute exercise‐induced lipolysis and increase in levels of fatty acid esters of hydroxy fatty acids in adipose tissue are impaired in obese and aged mice

Experimental Physiology, EarlyView.
Abstract Improving adipose tissue (AT) metabolism through exercise might increase production of lipokines from the fatty acid esters of hydroxy fatty acids (FAHFA) family. Although exercise training can increase insulin sensitivity and levels of specific FAHFA in AT and the circulation in humans, the effects of acute exercise on FAHFA levels remain ...
Marko Mitrovic, Olga Horakova, Martin Riecan, Veronika Kleinova, Tomas Cajka, Lenka Rossmeislova, Ondrej Kuda, Martin Rossmeisl   +7 more
wiley   +1 more source

Distinct Plasma LPC Signatures Differentiate COVID-19 Sepsis from Other Sepsis Aetiologies

Biomedicines
Background/Objectives: Low levels of lysophosphatidylcholine (LPC) in the blood can be used as a diagnostic marker for sepsis. SARS-CoV-2 infection, a more recent cause of sepsis, shares similarities with non-SARS-CoV-2 sepsis but also exhibits distinct ...
Vlad Pavel, Patricia Mester, Marcus Höring, Gerhard Liebisch, Stephan Schmid, Martina Müller, Christa Buechler   +6 more
doaj   +1 more source

Arrhythmogenic age-related effects of lysophosphatidylcholine in the rat heart.

, 1990
Ventricular arrhythmias are the most common cause of death among patients with coronary artery disease; this is more evident in the elderly, who tend to have more severe coronary artery disease and age-dependent modifications of cardiac ...
Abete P., Caccese P, LEOSCO, DARIO, Caccese P., Orlando M, FERRARA, NICOLA, Orlando M., De Caprio L, Rengo F., De Caprio L., ABETE, PASQUALE   +10 more
core