Results 1 to 10 of about 6,447 (173)
Practical Laboratory Medicine, 2023 Background and objectives: Very long-chain fatty acyl-lysophosphatidylcholines (VLCFA-LysoPCs) are measured in dried blood spots (DBS) for identifying X-linked adrenoleukodystrophy (X-ALD) and other inherited peroxisomal disorders.
Rita Christopher
exaly +4 more sources
Untargeted Metabolomics Reveals Metabolic Reprogramming Linked to HCC Risk in Late Diagnosed Tyrosinemia Type 1 [PDF]
MetabolitesBackground/Objectives: Tyrosinemia type 1 (HT-1) is a treatable inherited disorder characterized by disrupted tyrosine metabolism, leading to severe liver, renal, and occasionally neurological dysfunction.
Anna Sidorina +10 more
doaj +2 more sources
Identification of plasma lipid metabolism and potential biomarkers in patients with different coronary occlusive acute myocardial infarction [PDF]
Frontiers in Cell and Developmental BiologyAcute myocardial infarction (AMI) is the main cause of death worldwide. We aim to compare the differences in plasma lipid metabolites between AMI patients and normal controls to search for biomarker molecules for AMI with different infarct sites.
Hao Chen +4 more
doaj +2 more sources
Weizmannia coagulans BC99 Ameliorates Obesity and Associated Inflammation by Remodeling the Gut Microbiota and Regulating Lysophosphatidylcholine and Conjugated Bile Acid Metabolism [PDF]
MetabolitesBackground: Obesity is closely related to dysbiosis. Probiotics may improve metabolism and alleviate inflammation by regulating microbial–host interaction. Methods: Obesity was induced in rats by feeding a high-fat diet, followed by gavage administration
Yujia Pan +9 more
doaj +2 more sources
Microbiology SpectrumGut microbiota have been found to promote hypoxia-induced intestinal injury. However, the role of gut microbiota in high-altitude pulmonary edema (HAPE), the preventive effect of synbiotic on HAPE, and the mechanisms by which they might work remain ...
Jingming Jia, Anhua Wang
exaly +3 more sources
Metabolic profiles of squamous cell lung carcinoma and diagnostic model construction [PDF]
Scientific ReportsCancer cells exhibit metabolic reprogramming to fulfill their increased demands for abnormal growth and proliferation. We studied metabolic profiles of squamous cell lung carcinoma (LUSC).
Kyung Soo Kim +5 more
doaj +2 more sources
Lysophosphatidylcholines and phosphatidylcholines as biomarkers for stroke recovery
Frontiers in Neurology, 2022 Stroke is a serious global public health issue, associated with severe disability and high mortality rates. Its early detection is challenging, and no effective biomarkers are available.
Meiling Huang +8 more
doaj +1 more source
Frontiers in Endocrinology, 2023 AimsThis study aimed to explore associations of mannan-binding lectin-associated serine protease (MASP) levels in early pregnancy with gestational diabetes mellitus (GDM).
Ming Gao +16 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2021 Aortic dissection (AD) is a catastrophic cardiovascular emergency with a poor prognosis, and little preceding symptoms. Abnormal lipid metabolism is closely related to the pathogenesis of AD.
Huang Huang +14 more
doaj +1 more source
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source