Results 11 to 20 of about 6,447 (173)

Lysophosphatidylcholines and Chlorophyll-Derived Molecules from the Diatom Cylindrotheca closterium with Anti-Inflammatory Activity [PDF]

Marine Drugs, 2020
Microalgae have been shown to be excellent producers of lipids, pigments, carbohydrates, and a plethora of secondary metabolites with possible applications in the pharmacological, nutraceutical, and cosmeceutical sectors. Recently, various microalgal raw
Chiara Lauritano, Kirsti Helland, Gennaro Riccio, Jeanette H. Andersen, Adrianna Ianora, Espen H. Hansen   +5 more
doaj   +2 more sources

Product inhibition of secreted phospholipase A2 may explain lysophosphatidylcholines' unexpected therapeutic properties [PDF]

Journal of Inflammation, 2008
Background Lysophosphatidylcholines (lysoPCs) are products of phospholipase A2 (PLA2) enzyme activity, and like the enzyme, have a direct role in toxic inflammatory responses in variety of organ systems.
Lucena Angel, Yao Lihua, Cunningham Timothy J   +2 more
doaj   +2 more sources

Independent and Opposite Associations Between Branched-Chain Amino Acids and Lysophosphatidylcholines With Incident Diabetes in Thais

Metabolites, 2020
Branched-chain amino acids (BCAAs) and lysophosphatidylcholines (LPCs) have been reported to be associated with diabetes. The purpose of the present study was to investigate the relative contributions of BCAAs and LPCs to the progression of prediabetes ...
La-or Chailurkit, Nitchawat Paiyabhroma, Piyamit Sritara, Prin Vathesatogkit, Sukit Yamwong, Nisakron Thonmung, Boonsong Ongphiphadhanakul   +6 more
doaj   +2 more sources

Lipid profiling of Parkinson’s disease brain highlights disruption in Lysophosphatidylcholines, and triacylglycerol metabolism

npj Parkinson's Disease
Parkinson’s disease (PD) is the second most common neurodegenerative disorder following Alzheimer’s disease, with a 1.5 times higher prevalence in males.
Ali Yilmaz, Nadia Ashrafi, Romana Ashrafi, Sumeyya Akyol, Nazia Saiyed, Ieva Kerševičiūtė, Migle Gabrielaite, Juozas Gordevicius, Stewart F. Graham   +8 more
doaj   +2 more sources

Nettle supplementation improves antioxidant status and modulates inflammatory response by altering lysophosphatidylcholines and enterolactone metabolism in dairy cows

Animal Nutrition
Nettle is not only a nutrient-rich forage but also possesses the potential to act as a nutritional and physiological regulator. This study investigated the effects of supplementing nettle hay into the total mixed rations (TMR) on milk yield, milk ...
Qian Zhang, Na Ta, Jize Zhang, Xiaozhen Liu, He Ding, Xiaoqing Zhang   +5 more
doaj   +2 more sources

Altered plasma lysophosphatidylcholines and amides in non-obese and non-diabetic subjects with borderline-to-moderate hypertriglyceridemia: a case-control study. [PDF]

PLoS ONE, 2015
Hypertriglyceridemia (HTG) is a risk factor for atherosclerotic cardiovascular disease (CVD). We investigated alterations in plasma metabolites associated with borderline-to-moderate HTG (triglycerides (TG) 150-500 mg/dL).
Sae Young Lee, Minjoo Kim, Saem Jung, Sang-Hyun Lee, Jong Ho Lee   +4 more
doaj   +2 more sources

Association between the third trimester maternal serum metabolome and child growth and development through the first year of life

Scientific Reports
Evidence suggests that maternal metabolome may be associated with child health outcomes. We analyzed the association between the maternal metabolome between 28–35 gestational weeks and child growth and development during the first year.
Samary da Silva Rosa Freire, Marina Padilha, Ana Lorena Lima Ferreira, Raquel Machado Schincaglia, Amanda Caroline Cunha Figueiredo, Nathalia Cristina Freitas-Costa, Xiaofei Yin, Lorraine Brennan, Gilberto Kac   +8 more
doaj   +2 more sources

Broad Metabolome Alterations Associated with the Intake of Oral Contraceptives Are Mediated by Cortisol in Premenopausal Women

Metabolites, 2021
The use of oral contraceptives (OCs) has been associated with elevated blood cortisol concentrations. However, metabolic downstream effects of OC intake are not well described.
Clara Eick, Johanna Klinger-König, Stephanie Zylla, Anke Hannemann, Kathrin Budde, Ann Kristin Henning, Maik Pietzner, Matthias Nauck, Henry Völzke, Hans J. Grabe, Johannes Hertel   +10 more
doaj   +1 more source

Metabolomic signatures of SSRI exposure during neural differentiation and correlation of lysophosphatidylcholines with early symptoms of neurodevelopmental disorders. [PDF]

EBioMedicine
Background Selective serotonin reuptake inhibitors (SSRIs) are often prescribed during pregnancy. Epidemiological studies examining in-utero SSRI exposure and neurodevelopmental outcomes such as autism and ADHD have produced mixed results, in part due to
Arora A, Vacy K, Marques C, Degeratu MO, Mastropasqua F, Humphrey J, Ye X, Oksanen M, Vuillermin P, Ponsonby AL, Lanekoff I, Tammimies K, Barwon Infant Study Investigator Group.   +12 more
europepmc   +2 more sources

Metabolic Profiling of Plasma in Different Calving Body Condition Score Cows Using an Untargeted Liquid Chromatography-Mass Spectrometry Metabolomics Approach

Animals, 2020
This study was undertaken to identify metabolite differences in plasma of dairy cows with a normal or high calving body condition score (CBCS), using untargeted liquid chromatography-mass spectrometry (LC-MS) metabolomics.
Jian Wang, Chuang Zhang, Qingyao Zhao, Congcong Li, Shuang Jin, Xianhong Gu   +5 more
doaj   +1 more source