Results 21 to 30 of about 5,247 (197)
Methods for the preparation of lysophosphatidylcholine
Journal of Pharmacy and Pharmacology, 1971 Abstract The surfactant and solubilizing properties of lysophosphatidylcholine (LPC) could have industrial uses if it became available in technical quantity and purity. The two most promising routes for obtaining it are isolation from cereal starches and mono-deacylation of egg phosphatidylcholine (PC). Baker's yeast autolysed by Letters'
D S, Merryfield, J J, Wren
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Journal of Lipid Research, 1992 A water-soluble fluorescent phosphatidylcholine, 1,2-bis[4-(1-pyreno-butanoyl]-sn-glycero-3-phosphocholine (DPybPC) has been used to develop a sensitive, continuous assay for pure lecithin:cholesterol acyltransferase (LCAT) in solution.
FS Bonelli, A Jonas
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ATP Release Drives Inflammation with Lysophosphatidylcholine [PDF]
ImmunoHorizons, 2020 Abstract Lysophosphatidylcholine (LPC), a dominant lipid component of oxidized low-density lipoprotein, plays a major role in inflammation associated with atherosclerosis and neurodegenerative disorders. It activates inflammatory responses from macrophages, neuronal cells, and endothelial cells.
Sana, Ismaeel, Ayub, Qadri
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The presence of lysophosphatidylcholine in chromaffin granules [PDF]
Biochemical Journal, 1980 Lysophosphatidylcholine is thought to be a characteristic component of the chromaffin granules in adrenal glands. By the use of a t.l.c. system that resolves minor phospholipids satisfactorily, this subcellular location was confirmed in the present study in bovine glands.
G, Arthur, A, Sheltawy
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Frontiers in MedicineMorbid obesity represents the most severe form of obesity and is associated with increased cardiometabolic risk, including type 2 diabetes and cardiovascular complications. Current diagnostic approaches rely on anthropometric measures, failing to capture
Eleonora Stefanini +18 more
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Journal of Inflammation, 2008 Background Lysophosphatidylcholines (lysoPCs) are products of phospholipase A2 (PLA2) enzyme activity, and like the enzyme, have a direct role in toxic inflammatory responses in variety of organ systems.
Lucena Angel +2 more
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Defining Acute Coronary Syndrome through Metabolomics
Metabolites, 2021 As an emerging platform technology, metabolomics offers new insights into the pathomechanisms associated with complex disease conditions, including cardiovascular diseases.
Arun Surendran +4 more
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Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes [PDF]
Journal of Lipid Research, 2008 The pathogenesis of nonalcoholic steatohepatitis (NASH) is unclear, despite epidemiological data implicating FFAs. We studied the pathogenesis of NASH using lipoapoptosis models. Palmitic acid (PA) induced classical apoptosis of hepatocytes. PA-induced lipoapoptosis was inhibited by acyl-CoA synthetase inhibitor but not by ceramide synthesis inhibitors,
Myoung Sook Han +15 more
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Анналы клинической и экспериментальной неврологииPost-stroke cognitive impairment (PSCI) is a major complication of cerebrovascular disease, spanning from mild cognitive impairment to dementia. PSCI pathogenesis involves complex mechanisms, including neuroinflammation, oxidative stress, and neuronal ...
Chandra Wirawan +5 more
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Frontiers in Pharmacology, 2022 The 9-(R)-HODE is an active compound isolated from cortex lycii that showed significant hypoglycemic effects in our previous in vitro study. In this study, 9-(R)-HODE’s in vivo hypoglycemic activity and effect on alleviating diabetic complications ...
Yueqiu Liu +14 more
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