Results 21 to 30 of about 6,447 (173)

The maternal blood lipidome is indicative of the pathogenesis of severe preeclampsia

open access: yesJournal of Lipid Research, 2021
Preeclampsia is a pregnancy-specific syndrome characterized by hypertension and proteinuria after 20 weeks of gestation. However, it is not well understood what lipids are involved in the development of this condition, and even less is known how these ...
Bing He   +7 more
doaj   +1 more source

Lowering of lysophosphatidylcholines in ovariectomized rats by Curcuma comosa.

open access: yesPLoS ONE, 2022
Decline of ovarian function in menopausal women increases metabolic disease risk. Curcuma comosa extract and its major compound, (3R)-1,7-diphenyl-(4E,6E)-4,6-heptadien-3-ol (DPHD), improved estrogen-deficient ovariectomized (OVX) rat metabolic ...
Jetjamnong Sueajai   +7 more
doaj   +1 more source

Fetal Exposure to Maternal Smoking and Neonatal Metabolite Profiles

open access: yesMetabolites, 2022
Fetal tobacco exposure has persistent effects on growth and metabolism. The underlying mechanisms of these relationships are yet unknown. We investigated the associations of fetal exposure to maternal smoking with neonatal metabolite profiles.
Kim N. Cajachagua-Torres   +6 more
doaj   +1 more source

Circulating lysophosphatidylcholines in early pregnancy and risk of gestational diabetes in Chinese women [PDF]

open access: yes, 2020
Objectives: This study aimed to explore associations of lysophosphatidylcholines (LPCs) in early pregnancy with gestational diabetes mellitus (GDM), and whether LPCs mediated the associations of bile acids with GDM risk or had interactive effects with ...
Liu, Jinnan   +11 more
core   +2 more sources

Comprehensive lipidomics reveals phenotypic differences in hepatic lipid turnover in ALD and NAFLD during alcohol intoxication⋆

open access: yesJHEP Reports, 2021
Background & Aims: In experimental models, alcohol induces acute changes in lipid metabolism that cause hepatocyte lipoapoptosis and inflammation. Here we study human hepatic lipid turnover during controlled alcohol intoxication.
Mads Israelsen   +10 more
doaj   +1 more source

Serum lipidomic determinants of human diabetic neuropathy in type 2 diabetes

open access: yesAnnals of Clinical and Translational Neurology, 2022
Objective The serum lipidomic profile associated with neuropathy in type 2 diabetes is not well understood. Obesity and dyslipidemia are known neuropathy risk factors, suggesting lipid profiles early during type 2 diabetes may identify individuals who ...
Farsad Afshinnia   +11 more
doaj   +1 more source

Plasma Lipidomics Analysis Reveals the Potential Role of Lysophosphatidylcholines in Abdominal Aortic Aneurysm Progression and Formation

open access: yes, 2023
Abdominal aortic aneurysm (AAA) is hallmarked by irreversible dilation of the infrarenal aorta. Lipid deposition in the aortic wall and the potential importance of a lipid disorder in AAA etiology highlight the need to explore lipid variation during AAA ...
Jianqiang Wu   +9 more
core   +1 more source

Continuous fluorescence assay for lecithin:cholesterol acyltransferase using a water-soluble phosphatidylcholine.

open access: yesJournal of Lipid Research, 1992
A water-soluble fluorescent phosphatidylcholine, 1,2-bis[4-(1-pyreno-butanoyl]-sn-glycero-3-phosphocholine (DPybPC) has been used to develop a sensitive, continuous assay for pure lecithin:cholesterol acyltransferase (LCAT) in solution.
FS Bonelli, A Jonas
doaj   +1 more source

Epilipidomics of Senescent Dermal Fibroblasts Identify Lysophosphatidylcholines as Pleiotropic Senescence-Associated Secretory Phenotype (SASP) Factors

open access: yes, 2020
Während des Alterns sammelt die Haut seneszente Zellen an. Die vorübergehende Anwesenheit von seneszenten Zellen, gefolgt von ihrer Clearance durch das Immunsystem, ist wichtig für die Gewebereparatur und Homöostase.
Pils, Vera; orcid:   +26 more
core   +1 more source

Isoprenoid Derivatives of Lysophosphatidylcholines Enhance Insulin and GLP-1 Secretion through Lipid-Binding GPCRs

open access: yes, 2021
Insulin plays a significant role in carbohydrate homeostasis as the blood glucose lowering hormone. Glucose-induced insulin secretion (GSIS) is augmented by glucagon-like peptide (GLP-1), a gastrointestinal peptide released in response to ingesting ...
Daria Kamińska   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy