Results 231 to 240 of about 180,932 (288)

Cholesterol transfer proteins promote Atg-independent ER clearance by lysosomes. [PDF]

Cell Rep
Wang R, Fortier TM, Sun X, Chai F, Velentzas PD, Baehrecke EH.   +5 more
europepmc   +1 more source

The TG2/LRP1 Pathway for T Cell Activation by Post-Translationally Modified Antigens. [PDF]

Immunol Rev
Sewa AS, Yang FC, Khosla C.
europepmc   +1 more source

FIS1 dependent peripheral fission exacerbates mitochondrial fragmentation and dysfunction in prion diseases. [PDF]

Front Neurosci
Gou F, Li Z, Li J, Yang D, Zhao M, Wang D, Wen P, Sun Z, Wang J, Fan Q, Dai Y, Zhao D, Yang L.   +12 more
europepmc   +1 more source

The Lysosome-Cathepsin Axis in Pancreatic Cancer: Mechanisms of Stromal Remodeling, Immune Evasion, and Therapy Resistance. [PDF]

Biomolecules
Mazej Jeram N, Senjor E, Kos J, Perišić Nanut M.   +3 more
europepmc   +1 more source

Fragile mitophagy in long COVID: a proposed recovery-failure endotype for post-exertional malaise. [PDF]

Front Med (Lausanne)
Groysman R.
europepmc   +1 more source

Intracellular Nanopharmacology of Trastuzumab Deruxtecan Reveals Lysosome-Centered Organelle Vulnerabilities in HER2-Positive Breast Cancer Cells. [PDF]

ACS Nano Med
Tagliatti E, Gagliani MC, Bellese G, Salamat S, Crippa M, Sollazzo M, Abbona A, Paccagnella M, Arnaldi P, Rossi L, Petretto A, Rusmini P, Crippa V, Merlano MC, Garrone O, Porcelli AM, Matteoli M, Falletta P, Castagnola P, Cortese K.   +19 more
europepmc   +1 more source

Correction to "Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian cancer cells in combination with proteasome or lysosome inhibitors". [PDF]

Mol Oncol
europepmc   +1 more source

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Lipids and Lysosomes

Current Drug Metabolism, 2012
Lysosomes are cytoplasmic organelles delimited by a single membrane and filled with a variety of hydrolytic enzymes active at acidic pH and collectively capable to degrade the vast majority of macromolecules entering lysosomes via endocytosis, phagocytosis or autophagy.
Hamer, Isabelle, Van Beersel, Guillaume, Arnould, Thierry, Jadot, Michel   +3 more
openaire   +3 more sources

Lysosomal Membrane Proteomics and Biogenesis of Lysosomes

Molecular Neurobiology, 2005
This review focuses on events involved in the biogenesis of the lysosome. This organelle contains a diverse array of soluble, luminal proteins capable of digesting all the macromolecules in the cell. Altered function of lysosomes or its constituent enzymes has been implicated in a host of human pathologies, including storage diseases, cancer, and ...
Richard D, Bagshaw, Don J, Mahuran, John W, Callahan   +2 more
openaire   +2 more sources