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Poxvirus A52 protein subverts autophagy flux by blocking autophagosome-lysosome fusion to promote viral replication. [PDF]

open access: yesPLoS Pathog
Niu K   +9 more
europepmc   +1 more source

The Fragile Balance: Autophagy's Role in Neurodegenerative Disease Progression. [PDF]

open access: yesCurr Neuropharmacol
Bhushan B   +5 more
europepmc   +1 more source
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Lysosomal Biogenesis in Lysosomal Storage Disorders

Experimental Cell Research, 1997
Lysosomal biogenesis is an orchestration of the structural and functional elements of the lysosome to form an integrated organelle and involves the synthesis, targeting, functional residence, and turnover of the proteins that comprise the lysosome. We have investigated lysosomal biogenesis during the formation and dissipation of storage vacuoles in two
Karageorgos, L.   +6 more
openaire   +4 more sources

Lysosomal proteinases

Acta Histochemica, 1987
A characteristic of lysosomal cysteine proteinases is given by their kinetic constants with specific substrates, their sequence homology, and their reactivity with monospecific polyclonal antibodies.
H, Kirschke, B, Wiederanders
openaire   +2 more sources

Lysosomes, Lysosomal Enzymes, and Cancer

1992
Publisher Summary Lysosomes are membrane-enclosed cytoplasmic organelles, which posses an acidic interior that contains many hydrolytic enzymes. Their major function is in the the degradation of macromolecules, which may be cellular or foreign in origin.
M J, Boyer, I F, Tannock
openaire   +2 more sources

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