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Poxvirus A52 protein subverts autophagy flux by blocking autophagosome-lysosome fusion to promote viral replication. [PDF]
Niu K +9 more
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Integrated biochemical, histological, and transcriptomic analyses reveal dose-dependent effects of sodium alginate on the physiology of Meretrix meretrix. [PDF]
Wang Y +8 more
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The Fragile Balance: Autophagy's Role in Neurodegenerative Disease Progression. [PDF]
Bhushan B +5 more
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The lysosome and proteostatic stress at the intersection of pediatric neurological disorders and adult neurodegenerative diseases. [PDF]
Lane-Donovan C, Paredes M, Kao AW.
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Advances in Pharmacological Treatments for Cystinosis: Cysteamine and Its Alternatives. [PDF]
Carneiro A, Jones DH.
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Lysosomal Biogenesis in Lysosomal Storage Disorders
Experimental Cell Research, 1997Lysosomal biogenesis is an orchestration of the structural and functional elements of the lysosome to form an integrated organelle and involves the synthesis, targeting, functional residence, and turnover of the proteins that comprise the lysosome. We have investigated lysosomal biogenesis during the formation and dissipation of storage vacuoles in two
Karageorgos, L. +6 more
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Acta Histochemica, 1987
A characteristic of lysosomal cysteine proteinases is given by their kinetic constants with specific substrates, their sequence homology, and their reactivity with monospecific polyclonal antibodies.
H, Kirschke, B, Wiederanders
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A characteristic of lysosomal cysteine proteinases is given by their kinetic constants with specific substrates, their sequence homology, and their reactivity with monospecific polyclonal antibodies.
H, Kirschke, B, Wiederanders
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Lysosomes, Lysosomal Enzymes, and Cancer
1992Publisher Summary Lysosomes are membrane-enclosed cytoplasmic organelles, which posses an acidic interior that contains many hydrolytic enzymes. Their major function is in the the degradation of macromolecules, which may be cellular or foreign in origin.
M J, Boyer, I F, Tannock
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