Results 201 to 210 of about 239,873 (360)

MO047MEGALIN/CUBILIN-LYSOSOME-MEDIATED ALBUMIN REABSORPTION IS INVOLVED IN THE TUBULAR CELL ACTIVATION OF NLRP3 INFLAMMASOME AND TUBULOINTERSTITIAL INFLAMMATION [PDF]

, 2016
Dan Liu, Bi‐Cheng Liu
openalex   +1 more source

The SARS-CoV-2 nucleocapsid protein associates with the replication organelles before viral assembly at the Golgi/ERGIC and lysosome-mediated egress

, 2021
Katharina M. Scherer, Luca Mascheroni, George Carnell, Lucia C. S. Wunderlich, Stanislaw Makarchuk, Marius Brockhoff, Ioanna Mela, Ana Fernández‐Villegas, Max Barysevich, Hazel Stewart, Maria Suau Sans, Charlotte George, Jacob R. Lamb, Gabriele S. Kaminski Schierle, Jonathan L. Heeney, Clemens F. Kaminski   +15 more
openalex   +1 more source

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

Huntington's disease-associated ankyrin repeat palmitoyl transferases are rate-limiting factors in lysosome formation and fusion. [PDF]

PLoS Genet
Szenci G, Boda A, Nagy A, Károlyi D, Rubics A, Szőke Z, Falcsik G, Kovács T, Lőrincz P, Juhász G, Takáts S.   +10 more
europepmc   +1 more source

1α,25-Dihydroxyvitamin D3 reduces uropathogenic E. coli persistence in bladder epithelial cells by restoring lysosome acidification

Hao Yin, Xue Yi, Xin Wang
openalex   +2 more sources

The position of lysosomes within the cell determines their luminal pH [PDF]

, 2016
Danielle Johnson, Philip P. Ostrowski, Valentin Jaumouillé, Sergio Grinstein   +3 more
openalex   +1 more source

Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell Death

Advanced Science, EarlyView.
Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan, Huzi Zhao, Pei Zhang, Pengfei Yu, Yunfei Ji, Gang Chen, Hongli Jin, Yanfang Liu, Jin Liu, Zhe‐Sheng Chen, Aiping Lyu, Xinmiao Liang, Yang Chen   +12 more
wiley   +1 more source

Lysophosphatidylcholine Acyltransferase 1-Phosphatidylcholine Axis Protects Nucleus Pulposus Cells From Ferroptosis by Facilitating Lysosomal Repair via Interaction With the Endoplasmic Reticulum. [PDF]

Neurospine
Li C, Jiang J, Tu S, Dong Y, Zhang W, Chen X.   +5 more
europepmc   +1 more source

Microtubules Support Production of Starvation-induced Autophagosomes but Not Their Targeting and Fusion with Lysosomes [PDF]

, 2006
Ephraim Fass, Elena Shvets, Ilan Degani, Koret Hirschberg, Zvulun Elazar   +4 more
openalex   +1 more source

Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles

Advanced Science, EarlyView.
The proximity labeling enzyme APEX2 is displayed on extracellular vesicle (EV) surfaces via genetic fusion with EV‐sorting scaffolds, enabling in situ biotinylation of native surface proteins, adsorbed corona components, and interacting cellular proteins.
Wenyi Zheng, Metoboroghene Mowoe, Wenqing Hou, Daniel W. Hagey, Koshi Imami, Samir EL Andaloussi   +5 more
wiley   +1 more source