Results 41 to 50 of about 119,571 (264)

Serum amyloid P component promotes formation of distinct aggregated lysozyme morphologies and reduces toxicity in Drosophila flies expressing F57I lysozyme.

PLoS ONE, 2020
Many conflicting reports about the involvement of serum amyloid P component (SAP) in amyloid diseases have been presented over the years; SAP is known to be a universal component of amyloid aggregates but it has been suggested that it can both induce and
Liza Bergkvist, Daniel R Richards, Ana Bernardo-Gancedo, Janet R Kumita, Peter R Nilsson, Ann-Christin Brorsson   +5 more
doaj   +1 more source

A novel hybrid protein composed of superoxide-dismutase-active Cu(II) complex and lysozyme

Scientific Reports, 2023
A novel hybrid protein composed of a superoxide dismutase-active Cu(II) complex (CuST) and lysozyme (CuST@lysozyme) was prepared. The results of the spectroscopic and electrochemical analyses confirmed that CuST binds to lysozyme.
Tetsundo Furuya, Daisuke Nakane, Kenichi Kitanishi, Natsuki Katsuumi, Arshak Tsaturyan, Igor N. Shcherbakov, Masaki Unno, Takashiro Akitsu   +7 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Oral administration of lysozyme protects against injury of ileum via modulating gut microbiota dysbiosis after severe traumatic brain injury

Frontiers in Cellular and Infection Microbiology
ObjectiveThe current study sought to clarify the role of lysozyme-regulated gut microbiota and explored the potential therapeutic effects of lysozyme on ileum injury induced by severe traumatic brain injury (sTBI) and bacterial pneumonia in vivo and in ...
Weijian Yang, Weijian Yang, Weijian Yang, Weijian Yang, Weijian Yang, Caihua Xi, Caihua Xi, Caihua Xi, Caihua Xi, Caihua Xi, Haijun Yao, Haijun Yao, Haijun Yao, Haijun Yao, Haijun Yao, Qiang Yuan, Qiang Yuan, Qiang Yuan, Qiang Yuan, Qiang Yuan, Jun Zhang, Jun Zhang, Jun Zhang, Jun Zhang, Jun Zhang, Qifang Chen, Qifang Chen, Qifang Chen, Qifang Chen, Qifang Chen, Gang Wu, Gang Wu, Gang Wu, Gang Wu, Gang Wu, Jin Hu, Jin Hu, Jin Hu, Jin Hu, Jin Hu   +39 more
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Lysozyme Modification Using Proteolytic Enzymes

Molecules, 2023
The lysozyme in the chicken egg white consists of various bioactive amino acids. However, these compounds are inactive when they are in the sequence of parent proteins. They become active only when isolated from these proteins.
Łukasz Tomczyk, Grzegorz Leśnierowski, Renata Cegielska-Radziejewska   +2 more
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Lysozyme Inhibitors as Tools for Lysozyme Profiling: Identification and Antibacterial Function of Lysozymes in the Hemolymph of the Blue Mussel

Molecules, 2023
Lysozymes are universal components of the innate immune system of animals that kill bacteria by hydrolyzing their main cell wall polymer, peptidoglycan.
Lise Vanderkelen, Joris M. Van Herreweghe, Chris W. Michiels   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Bactericidal Effect of Lysozyme

Антибиотики и Химиотерапия, 2020
Isolation of lysozyme from hemolymph of Alveonasus lahorensis (Acari: Parasitiformes, Argasidae) and Hyalomma marginatum (Acari: Parasitiformes, Ixodidae) with using ultrasound is described.
V. M. Podboronov, M. Yu. Shchelkanov, I. P. Smirnova, L. A. Burenkova, V. P. Novikova, V. A. Aristova, E. L. Novikova, G. G. Moskvitina, A. M. Ioffe   +8 more
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