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Minimal risk of Rabies lyssavirus spillover from bats in Israel: findings from long-term surveillance [PDF]
Frontiers in MicrobiologyRabies, caused by viruses of the genus Lyssavirus (family Rhabdoviridae), remains a persistent public health and veterinary challenge in Israel, a small but strategically positioned country at the crossroads of Africa, Asia, and Europe.
Maya Weinberg +9 more
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Structures of two lyssavirus glycoproteins trapped in pre- and post-fusion states and the implications on the spatial-temporal conformational transition along with pH-decrease. [PDF]
PLoS PathogensLyssavirus glycoprotein plays a crucial role in mediating virus entry and serves as the major target for neutralizing antibodies. During membrane fusion, the lyssavirus glycoprotein undergoes a series of low-pH-induced conformational transitions.
Fanli Yang +13 more
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Viruses, 2023 Rabies is a zoonotic and fatal encephalitis caused by members of the Lyssavirus genus. Among them, the most relevant species is Lyssavirus rabies, which is estimated to cause 60,000 human and most mammal rabies deaths annually worldwide.
Petra Drzewnioková +4 more
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Novel Bat Lyssaviruses Identified by Nationwide Passive Surveillance in Taiwan, 2018–2021
Viruses, 2022 Bat lyssaviruses were identified in Taiwan’s bat population during 2016–2017. The lyssavirus surveillance system was continuously conducted to understand the epidemiology.
Shu-Chia Hu +6 more
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PLoS Neglected Tropical Diseases, 2022 Neutralizing antibodies (nAbs) prevent the entry of viruses into permissive cells. Since nAbs represent correlates of protection against the Rabies lyssavirus, the presence of sufficient nAbs indicates effective vaccination.
Lara Schöler +4 more
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Viruses, 2023 We report the genetic characterization of two potentially novel rabies-related lyssaviruses identified from bats in Limpopo province, South Africa. Matlo bat lyssavirus (MBLV) was identified in two Miniopterus natalensis (Natal long-fingered) bats in ...
Natalie Viljoen +3 more
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Discovery of a novel bat lyssavirus in a Long-fingered bat (Myotis capaccinii) from Slovenia.
PLoS Neglected Tropical Diseases, 2023 Lyssaviruses are the causative agents of rabies, a zoonotic, fatal disease that is thought to be ancestral to bats. In the last decade, the detection of bat associated lyssaviruses is increasing also in Europe.
Danijela Černe +5 more
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Attenuation of clinical and immunological outcomes during SARS‐CoV‐2 infection by ivermectin
EMBO Molecular Medicine, 2021 The devastating pandemic due to SARS‐CoV‐2 and the emergence of antigenic variants that jeopardize the efficacy of current vaccines create an urgent need for a comprehensive understanding of the pathophysiology of COVID‐19, including the contribution of ...
Guilherme Dias de Melo +14 more
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International Journal of Infectious Diseases, 2022 Purpose: Without pre- or post-exposure prophylaxis, lyssaviruses cause rabies, an invariably fatal disease responsible for over 59,000 human deaths per year.
B. Auld +6 more
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Lyssaviruses in Insectivorous Bats, South Africa, 2003–2018
Emerging Infectious Diseases, 2020 We detected 3 lyssaviruses in insectivorous bats sampled in South Africa during 2003–2018. We used phylogenetic analysis to identify Duvenhage lyssavirus and a potentially new lyssavirus, provisionally named Matlo bat lyssavirus, that is related to West ...
Jessica Coertse +6 more
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