Results 41 to 50 of about 9,235 (254)

mAb therapy controls CNS‐resident lyssavirus infection via a CD4 T cell‐dependent mechanism

EMBO Molecular Medicine, 2023
Infections with rabies virus (RABV) and related lyssaviruses are uniformly fatal once virus accesses the central nervous system (CNS) and causes disease signs.
Kate E Mastraccio, Celeste Huaman, S. Coggins, Caitlyn Clouse, Madeline Rader, Lianying Yan, Pratyusha Mandal, Imran Hussain, Anwar E Ahmed, Trung Ho, Austin Feasley, Bang K Vu, Ina Smith, Wanda Markotter, Dawn L Weir, E. Laing, C. Broder, Brian C Schaefer   +17 more
semanticscholar   +1 more source

Isolation and Characterization of Cross-Reactive Human Monoclonal Antibodies That Potently Neutralize Australian Bat Lyssavirus Variants and Other Phylogroup 1 Lyssaviruses [PDF]

Viruses, 2021
Australian bat lyssavirus (ABLV) is a rhabdovirus that circulates in four species of pteropid bats (ABLVp) and the yellow-bellied sheath-tailed bat (ABLVs) in mainland Australia.
Dawn L. Weir, Si’Ana A. Coggins, Bang K. Vu, Jessica Coertse, Lianying Yan, Ina Smith, Eric D. Laing, Wanda Markotter, Christopher C. Broder, Brian C. Schaefer   +9 more
openalex   +2 more sources

The Challenge of Lyssavirus Infections in Domestic and Other Animals: A Mix of Virological Confusion, Consternation, Chagrin, and Curiosity. [PDF]

Pathogens
Lyssaviruses are RNA viruses in the Family Rhabdoviridae, Genus Lyssavirus. They represent the causative agents of acute, progressive encephalitis, known historically as rabies.
Rupprecht CE, Belsare AV, Cliquet F, Mshelbwala PP, Seetahal JFR, Wicker VV.   +5 more
europepmc   +2 more sources

The complete coding sequence of a rabies lyssavirus (RABV) detected in an American black bear (Ursus americanus) in Connecticut, USA. [PDF]

Microbiol Resour Announc
The complete coding sequence of a rabies lyssavirus (RABV) detected in a black bear (Ursus americanus) was generated. RNA extracted from brain tissues was amplified using reverse transcription followed by tiling PCR sequencing to obtain RABV whole viral ...
Helal ZH, Francesca Soriano N, Hyeon J-Y, Chun H, Sims M, Wheeler A, Risatti GR.   +6 more
europepmc   +2 more sources

Attenuation of clinical and immunological outcomes during SARS‐CoV‐2 infection by ivermectin

EMBO Molecular Medicine, 2021
The devastating pandemic due to SARS‐CoV‐2 and the emergence of antigenic variants that jeopardize the efficacy of current vaccines create an urgent need for a comprehensive understanding of the pathophysiology of COVID‐19, including the contribution of ...
Guilherme Dias de Melo, Françoise Lazarini, Florence Larrous, Lena Feige, Etienne Kornobis, Sylvain Levallois, Agnès Marchio, Lauriane Kergoat, David Hardy, Thomas Cokelaer, Pascal Pineau, Marc Lecuit, Pierre‐Marie Lledo, Jean‐Pierre Changeux, Hervé Bourhy   +14 more
doaj   +1 more source

Transmission dynamics of lyssavirus in Myotis myotis: mechanistic modelling study based on longitudinal seroprevalence data

Proceedings of the Royal Society B, 2023
We investigated the transmission dynamics of lyssavirus in Myotis myotis and Myotis blythii, using serological, virological, demographic and ecological data collected between 2015 and 2022 from two maternity colonies in northern Italian churches. Despite
Younjung Kim, S. Leopardi, D. Scaravelli, B. Zecchin, P. Priori, F. Festa, P. Drzewnioková, P. De Benedictis, P. Nouvellet   +8 more
semanticscholar   +1 more source

Communicating the risks of handling bats: analysing approaches used by Australian stakeholders in the context of Australian bat lyssavirus.

Australian Veterinary Journal, 2023
Australian bat lyssavirus (ABLV) is a member of the Lyssavirus genus of the Rhabdoviridae family and is found in Australian bat species. It is of public health concern because of the rabies-like syndrome it causes in humans, resulting in government ...
BP Liang, K. Wingett, K. Bosward, MR Taylor   +3 more
semanticscholar   +1 more source

Lyssaviruses in Insectivorous Bats, South Africa, 2003–2018

Emerging Infectious Diseases, 2020
We detected 3 lyssaviruses in insectivorous bats sampled in South Africa during 2003–2018. We used phylogenetic analysis to identify Duvenhage lyssavirus and a potentially new lyssavirus, provisionally named Matlo bat lyssavirus, that is related to West ...
Jessica Coertse, Colyn S. Grobler, Claude T. Sabeta, Ernest C.J. Seamark, Teresa Kearney, Janusz T. Paweska, Wanda Markotter   +6 more
doaj   +1 more source

Antigenic and genetic characterization of a divergent African virus, Ikoma lyssavirus [PDF]

, 2014
In 2009, a novel lyssavirus (subsequently named Ikoma lyssavirus, IKOV) was detected in the brain of an African civet (Civettictis civetta) with clinical rabies in the Serengeti National Park of Tanzania.
Alejandro Nunez, Alison J. Peel, Anthony R. Fooks, Ashley C. Banyard, Aubert, Brookes, Charles E. Rupprecht, Daniel Hicks, Daniel L. Horton, David Selden, Dean, Denise A. Marston, Dietzgen, Emma Wise, Estes, Ivan V. Kuzmin, Lodmell, Markotter, Sarah Cleaveland, Tiziana Lembo, Turmelle, Wilbur   +21 more
core   +2 more sources

Cross-neutralization activities of antibodies against 18 lyssavirus glycoproteins.

Japanese journal of infectious diseases (Print), 2023
Some lyssaviruses, including the rabies virus (RABV), induce lethal neurological symptoms in humans. However, commercial vaccines have only been evaluated for their efficacy against RABV and not against other lyssaviruses.
Yusuke Inoue, Yoshihiro Kaku, Michiko Harada, Keita Ishijima, Y. Kuroda, Kango Tatemoto, Milagros Virhuez-Mendoza, Ayano Nishino, Tsukasa Yamamoto, Satoshi Inoue, Aya Matsuu, Ken Maeda   +11 more
semanticscholar   +1 more source