Results 41 to 50 of about 9,882 (257)

Antigenic and genetic characterization of a divergent African virus, Ikoma lyssavirus [PDF]

, 2014
In 2009, a novel lyssavirus (subsequently named Ikoma lyssavirus, IKOV) was detected in the brain of an African civet (Civettictis civetta) with clinical rabies in the Serengeti National Park of Tanzania.
Alejandro Nunez, Alison J. Peel, Anthony R. Fooks, Ashley C. Banyard, Aubert, Brookes, Charles E. Rupprecht, Daniel Hicks, Daniel L. Horton, David Selden, Dean, Denise A. Marston, Dietzgen, Emma Wise, Estes, Ivan V. Kuzmin, Lodmell, Markotter, Sarah Cleaveland, Tiziana Lembo, Turmelle, Wilbur   +21 more
core   +2 more sources

A Preliminary Study on Bat Lyssavirus in Assam, India [PDF]

Indian Journal of Animal Research
Background: Rabies is a zoonotic disease caused by Lyssavirus of the family Rhabdoviridae, affecting all warm-blooded animals. Although a vast majority of the cases are canine-mediated, many cases of bat-mediated rabies in humans have been documented ...
Tinku Das, Jyoti B Dutta, Prasanta Boro, Shrikrishna Isloor, Sarosh Arif, Ananda Ram Boro, Uma Nahar Saikia   +6 more
openalex   +2 more sources

Transmission dynamics of lyssavirus in Myotis myotis: mechanistic modelling study based on longitudinal seroprevalence data

Proceedings of the Royal Society B, 2023
We investigated the transmission dynamics of lyssavirus in Myotis myotis and Myotis blythii, using serological, virological, demographic and ecological data collected between 2015 and 2022 from two maternity colonies in northern Italian churches. Despite
Younjung Kim, S. Leopardi, D. Scaravelli, B. Zecchin, P. Priori, F. Festa, P. Drzewnioková, P. De Benedictis, P. Nouvellet   +8 more
semanticscholar   +1 more source

Lyssaviruses in Insectivorous Bats, South Africa, 2003–2018

Emerging Infectious Diseases, 2020
We detected 3 lyssaviruses in insectivorous bats sampled in South Africa during 2003–2018. We used phylogenetic analysis to identify Duvenhage lyssavirus and a potentially new lyssavirus, provisionally named Matlo bat lyssavirus, that is related to West ...
Jessica Coertse, Colyn S. Grobler, Claude T. Sabeta, Ernest C.J. Seamark, Teresa Kearney, Janusz T. Paweska, Wanda Markotter   +6 more
doaj   +1 more source

Application of high-throughput sequencing to whole rabies viral genome characterisation and its use for phylogenetic re-evaluation of a raccoon strain incursion into the province of Ontario [PDF]

, 2017
Raccoon rabies remains a serious public health problem throughout much of the eastern seaboard of North America due to the urban nature of the reservoir host and the many challenges inherent in multi-jurisdictional efforts to administer co-ordinated and ...
Biek, Roman, Colville, Adam, Nadin-Davis, Susan A., Real, Leslie, Trewby, Hannah   +4 more
core   +1 more source

Molecular Characterization of Lyssaviruses Originating from Domestic and Wild Cats Provides an Insight on the Diversity of Lyssaviruses and a Risk of Rabies Transmission to Other Susceptible Mammals and Humans in South Africa

Pathogens, 2023
Rabies is one of the most significant public and veterinary health problems, causing approximately 59,000 human deaths annually in the developing countries of Asia and Africa.
Kefentse Tsie, Ernest Ngoepe, Baby Phahladira, Nelisiwe Khumalo, Claude Sabeta   +4 more
doaj   +1 more source

Frequency analysis of cytolytic T lymphocyte precursors (CTL-P) generated in vivo during lethal rabies infection of mice. II. Rabies virus genus specificity of CTL-P [PDF]

, 1984
Cytolytic T lymphocyte precursors (CTL-P) were sensitized in vivo by intraplantar infection of C57BL/6 mice with a lethal dose of rabies virus, strain ERA (ERA).
Aden, Baer, Berke, Cox, Fazekas De, Grimm, Koprowski, Minato, Reddehase, Reddehase, Reddehase, Rosenthal, Rosenthal, Schneider, Sethi, Shope, Shope, Stoker, Taswell, Wiktor, Wiktor, Zinkernagel, Zinkernagel   +22 more
core   +1 more source

Production, characterization, and antigen specificity of recombinant 62-71-3, a candidate monoclonal antibody for rabies prophylaxis in humans [PDF]

, 2013
Rabies kills many people throughout the developing world every year. The murine monoclonal antibody (mAb) 62-71-3 was recently identified for its potential application in rabies postexposure prophylaxis (PEP).
Anthony R. Fooks, Ashley C. Banyard, Bardor M., Benmansour A., Bianca Bulmer‐Thomas, Constantine D. G., Craig Dolleweerd, David Selden, Dietzschold B., Dietzschold B., Dietzschold B., Edward Wright, Fooks A. R., Friedrich Altmann, Gomord V., Hampson K., Hultberg A., Julian K.‐C. Ma, Knobel D. L., Lafay F., Lafon M., Leonard Both, Luo T. R., Ma J. K., Manning S. E., Mansfield K. L., McCormick A. A., Muhamuda K., Müller T., Prehaud C., Satpathy D. M., Seif I., Shantavasinkul P., Sudarshan M. K., Tacket C. O., Tekoah Y., Van Ree R., Warrell M., Wertheim H. F. L., World Health Organization, World Health Organization, Wright E., Zeitlin L.   +42 more
core   +1 more source

mAb therapy controls CNS‐resident lyssavirus infection via a CD4 T cell‐dependent mechanism

EMBO Molecular Medicine, 2023
Infections with rabies virus (RABV) and related lyssaviruses are uniformly fatal once virus accesses the central nervous system (CNS) and causes disease signs.
Kate E Mastraccio, Celeste Huaman, S. Coggins, Caitlyn Clouse, Madeline Rader, Lianying Yan, Pratyusha Mandal, Imran Hussain, Anwar E Ahmed, Trung Ho, Austin Feasley, Bang K Vu, Ina L Smith, Wanda Markotter, Dawn L Weir, E. Laing, C. Broder, Brian C Schaefer   +17 more
semanticscholar   +1 more source

Lyssavirus matrix protein cooperates with phosphoprotein to modulate the Jak-Stat pathway

Scientific Reports, 2019
Phosphoprotein (P) and matrix protein (M) cooperate to undermine the immune response to rabies virus (RABV) infections. While P is involved in the modulation of the Jak-Stat pathway through the cytoplasmic retention of interferon (IFN)-activated STAT1 ...
Florian Sonthonnax, Benoit Besson, Emilie Bonnaud, Grégory Jouvion, David Merino, Florence Larrous, Hervé Bourhy   +6 more
doaj   +1 more source