Results 51 to 60 of about 9,235 (254)

A Step Forward in Molecular Diagnostics of Lyssaviruses – Results of a Ring Trial among European Laboratories [PDF]

, 2013
Rabies is a lethal and notifiable zoonotic disease for which diagnostics have to meet the highest standards. In recent years, an evolution was especially seen in molecular diagnostics with a wide variety of different detection methods published ...
A Orlowska, A Vos, A Vos, Anita Huovilainen, Anthony R. Fooks, B Hoffmann, B Hoffmann, B Hoffmann, Bernard Brochier, Bernd Hoffmann, CM Freuling, Conrad M. Freuling, D David, Denise A. Marston, DT Hayman, E Picard-Meyer, E Robardet, EM Black, Engbert A. Kooi, Florence Cliquet, GJ Hughes, IV Kuzmin, J Coertse, JE Echevarria, JE Whitby, Jean Mooney, Kerstin Wernike, L Dacheux, L Dacheux, M Biswal, M Fischer, M Ito, Marcin Smreczak, Martin Beer, Mats Isaksson, Melina Fischer, Mihai Turcitu, ML East, Orhan Aylan, P Crepin, P De Benedictis, Peter Hostnik, PR Heaton, PR Wakeley, S Vazquez-Moron, S Wacharapluesadee, S Wacharapluesadee, SA Nadin-Davis, Sandra Revilla-Fernández, Sonia Vázquez-Morón, T Müller, T Nagaraj, Thomas B. Rasmussen, Thomas Müller, V Shankar, W Saengseesom, Wanda Markotter   +56 more
core   +14 more sources

A two-step lyssavirus real-time polymerase chain reaction using degenerate primers with superior sensitivity to the fluorescent antigen test [PDF]

, 2014
A generic two-step lyssavirus real-time reverse transcriptase polymerase chain reaction (qRT-PCR), based on a nested PCR strategy, was validated for the detection of different lyssavirus species.
De Craeye, Stéphane, Francart, Aurélie, Kalai, Michael, Lamoral, Sophie, Nazé, Florence, Suin, Vanessa, Van Gucht, Steven   +6 more
core   +4 more sources

The matrix protein of lyssavirus hijacks autophagosome for efficient egress by recruiting NEDD4 through its PPxY motif. [PDF]

Autophagy
Lyssaviruses are well-known worldwide and often cause fatal encephalitis. Previous studies have shown that autophagy is beneficial for the replication of rabies virus (RABV), the representative lyssavirus, but the detailed mechanism remains obscure.
Yuan Y, Fang A, Wang Z, Chen H, Fu ZF, Zhou M, Zhao L.   +6 more
europepmc   +2 more sources

Production, characterization, and antigen specificity of recombinant 62-71-3, a candidate monoclonal antibody for rabies prophylaxis in humans [PDF]

, 2013
Rabies kills many people throughout the developing world every year. The murine monoclonal antibody (mAb) 62-71-3 was recently identified for its potential application in rabies postexposure prophylaxis (PEP).
Anthony R. Fooks, Ashley C. Banyard, Bardor M., Benmansour A., Bianca Bulmer‐Thomas, Constantine D. G., Craig Dolleweerd, David Selden, Dietzschold B., Dietzschold B., Dietzschold B., Edward Wright, Fooks A. R., Friedrich Altmann, Gomord V., Hampson K., Hultberg A., Julian K.‐C. Ma, Knobel D. L., Lafay F., Lafon M., Leonard Both, Luo T. R., Ma J. K., Manning S. E., Mansfield K. L., McCormick A. A., Muhamuda K., Müller T., Prehaud C., Satpathy D. M., Seif I., Shantavasinkul P., Sudarshan M. K., Tacket C. O., Tekoah Y., Van Ree R., Warrell M., Wertheim H. F. L., World Health Organization, World Health Organization, Wright E., Zeitlin L.   +42 more
core   +1 more source

Australian bat lyssavirus

Australian Journal of General Practice, 2018
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Merritt, Tony, Taylor, Kathryn, Cox-Witton, Keren, Field, Hume, Wingett, Kate, Mendez, Diana, Power, Michelle, Durrheim, David   +7 more
openaire   +6 more sources

The Lyssavirus glycoprotein: A key to cross-immunity

Virology, 2016
Rabies is an acute viral encephalomyelitis in warm-blooded vertebrates, caused by viruses belonging to Rhabdovirus family and genus Lyssavirus. Although rabies is categorised as a neglected disease, the rabies virus (RABV) is the most studied amongst Lyssaviruses which show nearly identical infection patterns.
Sindisiwe Buthelezi, Heini W. Dirr, Ereck Chakauya, Rachel Chikwamba, Lennart Martens, Tsepo L. Tsekoa, Stoyan Stoychev, Elien Vandermarliere   +7 more
openalex   +4 more sources

Machine Learning Identifies Cellular and Exosomal MicroRNA Signatures of Lyssavirus Infection in Human Stem Cell-Derived Neurons

Frontiers in Cellular and Infection Microbiology, 2021
Despite being vaccine preventable, rabies (lyssavirus) still has a significant impact on global mortality, disproportionally affecting children under 15 years of age.
Ryan J. Farr, Nathan Godde, Christopher Cowled, Vinod Sundaramoorthy, Diane Green, Cameron Stewart, John Bingham, Carmel M. O’Brien, Carmel M. O’Brien, Megan Dearnley   +9 more
doaj   +1 more source

Lyssavirus matrix protein cooperates with phosphoprotein to modulate the Jak-Stat pathway

Scientific Reports, 2019
Phosphoprotein (P) and matrix protein (M) cooperate to undermine the immune response to rabies virus (RABV) infections. While P is involved in the modulation of the Jak-Stat pathway through the cytoplasmic retention of interferon (IFN)-activated STAT1 ...
Florian Sonthonnax, Benoit Besson, Emilie Bonnaud, Grégory Jouvion, David Merino, Florence Larrous, Hervé Bourhy   +6 more
doaj   +1 more source

Application of high-throughput sequencing to whole rabies viral genome characterisation and its use for phylogenetic re-evaluation of a raccoon strain incursion into the province of Ontario [PDF]

, 2017
Raccoon rabies remains a serious public health problem throughout much of the eastern seaboard of North America due to the urban nature of the reservoir host and the many challenges inherent in multi-jurisdictional efforts to administer co-ordinated and ...
Biek, Roman, Colville, Adam, Nadin-Davis, Susan A., Real, Leslie, Trewby, Hannah   +4 more
core   +1 more source

Review of Rabies Preventions and Control [PDF]

, 2017
Rabies is an acute viral infection of the central nervous system, caused by a lyssavirus in the family Rhabdoviridae. It is zoonotic viral disease that can affect all mammals, including humans, cats, dogs, and wildlife and farm animals.
Abdela, N. (Nejash), Balcha, C. (Chernet)   +1 more
core   +2 more sources