Results 11 to 20 of about 2,388 (199)
Utilisation of Chimeric Lyssaviruses to Assess Vaccine Protection against Highly Divergent Lyssaviruses [PDF]
Viruses, 2018 Lyssaviruses constitute a diverse range of viruses with the ability to cause fatal encephalitis known as rabies. Existing human rabies vaccines and post exposure prophylaxes (PEP) are based on inactivated preparations of, and neutralising antibody ...
Jennifer S. Evans +6 more
doaj +6 more sources
Genomic diversity and evolution of the lyssaviruses. [PDF]
PLoS ONE, 2008 Lyssaviruses are RNA viruses with single-strand, negative-sense genomes responsible for rabies-like diseases in mammals. To date, genomic and evolutionary studies have most often utilized partial genome sequences, particularly of the nucleoprotein and ...
Olivier Delmas +6 more
doaj +8 more sources
Comparative Neutralization Activity of Commercial Rabies Immunoglobulin against Diverse Lyssaviruses [PDF]
Vaccines, 2023 Novel lyssaviruses, the causative agents of rabies, continue to be described mostly due to increased surveillance in bat hosts. Biologicals for the prevention of rabies in humans have, however, remained largely unchanged for decades.
Jessica Coertse +3 more
doaj +3 more sources
Phylogeographic Aspects of Bat Lyssaviruses in Europe: A Review
Pathogens, 2023 During the last few decades, bat lyssaviruses have become the topic of intensive molecular and epidemiological investigations. Since ancient times, rhabdoviruses have caused fatal encephalitis in humans which has led to research into effective strategies
Heliana Dundarova +10 more
doaj +2 more sources
Molecular Detection of Rabies Lyssaviruses from Dogs in Southeastern Nigeria: Evidence of TransboundaryTransmission of Rabies in West Africa [PDF]
Viruses, 2020 Despite being the first country to register confirmed cases of Mokola and Lagos bat lyssaviruses (two very distant lyssaviruses), knowledge gaps, particularly on the molecular epidemiology of lyssaviruses, still exist in Nigeria. A total of 278 specimens
Ukamaka U Eze +5 more
doaj +2 more sources
Viruses, 2021 Lyssaviruses are neurotropic rhabdoviruses thought to be restricted to mammalian hosts, and to originate from bats. The identification of lyssavirus sequences from amphibians and reptiles by metatranscriptomics thus comes as a surprise and challenges the
Martina Oberhuber +7 more
doaj +2 more sources
Renewed Public Health Threat from Emerging Lyssaviruses [PDF]
Viruses, 2021 Pathogen discovery contributes to our knowledge of bat-borne viruses and is linked to the heightened interest globally in bats as recognised reservoirs of zoonotic agents.
Anthony R. Fooks +8 more
doaj +2 more sources
Lyssaviruses in Insectivorous Bats, South Africa, 2003–2018 [PDF]
Emerging Infectious Diseases, 2020 We detected 3 lyssaviruses in insectivorous bats sampled in South Africa during 2003–2018. We used phylogenetic analysis to identify Duvenhage lyssavirus and a potentially new lyssavirus, provisionally named Matlo bat lyssavirus, that is related to West ...
Jessica Coertse +6 more
doaj +2 more sources
The Global Phylogeography of Lyssaviruses - Challenging the 'Out of Africa' Hypothesis.
PLoS Neglected Tropical Diseases, 2016 Rabies virus kills tens of thousands of people globally each year, especially in resource-limited countries. Yet, there are genetically- and antigenically-related lyssaviruses, all capable of causing the disease rabies, circulating globally among bats ...
David T S Hayman +3 more
doaj +2 more sources
Quantifying Antigenic Relationships among the Lyssaviruses [PDF]
Journal of Virology, 2010 ABSTRACT All lyssaviruses cause fatal encephalitis in mammals. There is sufficient antigenic variation within the genus to cause variable vaccine efficacy, but this variation is difficult to characterize quantitatively: sequence analysis cannot yet provide detailed antigenic information, and antigenic neutralization data have been refractory ...
Horton, DL +10 more
openaire +6 more sources