Results 91 to 100 of about 165,472 (305)
We investigated the therapeutic potential and mechanism of chrysin in experimental diabetic retinal disease. Using a streptozotocin (STZ)‐induced diabetic mouse model and high‐glucose‐stimulated BV2 microglia, we revealed chrysin‐responsive pyroptosis‐associated signatures and identified GBP3 as a regulated node.
Qun Liu +9 more
wiley +1 more source
Killing of virally infected cells or tumor cells by cytotoxic T lymphocytes requires targeting of lytic granules to the junction between the CTL and its target.
Min Ming +4 more
doaj +1 more source
Abstract Studies investigating paleopathologies in sauropods remain scarce despite their relative abundance in the fossil record. In this study we report new occurrence of paleopathological features, corresponding to a neoplasm found in a middle caudal vertebra (MCT.R.2120) of an advanced titanosaur from the Presidente Prudente Formation (Bauru Basin ...
Maria Luiza Peres Bertolossi +5 more
wiley +1 more source
Effect of pH on PlyPl23 lytic activity.
PlyPl23 activity on P. larvae Pl02-23 at different pH values, ranging from 5 to 9. Relative lytic activity was obtained as the ratio between the lytic activity of each test and the highest value obtained (the reference value was 70.9% lytic activity ...
Leon D. Kluskens (640869) +5 more
core +1 more source
Intensive or organic farming systems may expose pigs to management or environmental challenges. Our preliminary results concluded that organic farming might enhance adaptive immune function, showing that improvements in welfare can translate into measurable immunological benefits, based on the correlation between welfare assessment and physiological ...
Dorotea Ippolito +15 more
wiley +1 more source
Characterising the adaptive t-cell immune response against Kaposi’s sarcoma-associated herpesvirus [PDF]
Kaposi’s sarcoma-associated herpesvirus (KSHV) is causally related to Kaposi’s sarcoma (KS), the most common malignancy in individuals with untreated HIV/AIDS.
Robey, R.C.
core
The algae-lytic ability of bacterium DC10 and the influence of environmental factors on the ability
A lysing-bacterium DC10, isolated from Dianchi Lake of Yunnan Province, was characterized to be Pseudomonas sp. It was able to lyse some algae well, such as Microcystis viridis, Selenastrum capricomutum, and so on.
Li, GB +4 more
core +1 more source
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga +2 more
wiley +1 more source
Immune Responses to Epstein-Barr Virus Lytic Proteins in Patients with Nasopharyngeal Carcinoma
Immune responses to three Epstein-Barr virus (EBV) lytic proteins, DNase, thymidine kinase (TK), and BMRF-1 gene products (50/52 kDa diffused early antigen, EA-D complex) were determined in EBV-infected control individuals and patients with ...
LIU, MEI-YING;HUANG, YU-TZU;SHEEN, TZUNG-SHIAHN;CHEN, JEN-YANG;TSAI, CHING-HWA ANN +1 more
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