Results 111 to 120 of about 165,472 (305)
Chemistry – A European Journal, EarlyView.A series of N‐acetylmuramic acid (MurNAc)‐based electrophilic inhibitors targeting Ape esterase was synthesized. Their inhibitory potency ranged from micromolar to submillimolar. The study probed binding contributions of stem peptide extension, replacing the anomeric methyl group with a benzyl, and α‐fluorination of the carbonyl to enhance ...
Dmytro Voskoboinyk, Martin E. Tanner
wiley +1 more source
VirusesVirus spread at the single-cell level is largely uncharacterized. We have designed and constructed a microfluidic device in which each nanowell contains a single, infected cell (donor) and a single, uninfected cell (recipient).
Wu Liu +4 more
doaj +1 more source
, 2014 Objectives: Reduced Natural Killer (NK) cell cytotoxic activity is a recurring finding in patients with Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis (CFS/ME).
Staines, Don +6 more
core
Equine Veterinary Journal, EarlyView.Abstract Background Proximal interphalangeal joint osteoarthritis (PIPJ OA) is a common cause of poor performance in the equine athlete; however, the supporting soft tissue structures surrounding the joint are seldom evaluated. Straight sesamoidean ligament injuries have been previously hypothesised to be concomitant with PIPJ OA; however, the ...
Charlotte K. Barton +3 more
wiley +1 more source
Tpl2/AP-1 enhances murine gammaherpesvirus 68 lytic replication
, 2010 How cellular factors regulate gammaherpesvirus lytic replication is not well understood. Here, through functional screening of a cellular kinase expression library, we identified mitogen-activated protein kinase kinase kinase 8 (MAP3K8/Tpl2) as a ...
Chen, Shijia +7 more
core +1 more source
Head &Neck, EarlyView.ABSTRACT Background To characterize the clinicoepidemiologic profile of HIV‐associated oral Kaposi sarcoma (OKS) and quantitatively synthesize its frequency, anatomical distribution, and temporal patterns across antiretroviral therapy (ART) eras. Methods Six databases and gray literature were searched.
Ericles Otávio +10 more
wiley +1 more source
Phage lytic enzymes: a history
Virologica Sinica, 2015 There are many recent studies regarding the efficacy of bacteriophage-related lytic enzymes: the enzymes of 'bacteria-eaters' or viruses that infect bacteria. By degrading the cell wall of the targeted bacteria, these lytic enzymes have been shown to efficiently lyse Gram-positive bacteria without affecting normal flora and non-related bacteria. Recent
openaire +3 more sources
Isolation and Characterization of Novel Lytic Bacteriophages Infecting Carbapenem-Resistant Pathogenic Diarrheagenic and Uropathogenic Escherichia Coli [PDF]
Kenneth Ssekatawa,1,2 Ibrahim Ntulume,3 Denis Karuhize Byarugaba,3 Slawomir Michniewski,4 Eleanor Jameson,5 Eddie M Wampande,6 Jesca Nakavuma3 1Department of Science Technical and Vocational Education, Makerere University, Kampala, Uganda; 2Africa Center
Ssekatawa K +6 more
core
K-RTA inhibits EBV lytic gene expression.
, 2013 A. K-RTA inhibits the EBV lytic gene expression in Akata cells. Akata (EBV+/KSHV-) cells were transfected with K-RTA or vector plasmid (5 µg DNA). EBV lytic replication was induced by anti-human-IgGs a day later (0, 1, 5, 10 µg/ml).
Dongsheng Xu (84949) +3 more
core +1 more source