Results 121 to 130 of about 152,902 (307)

H2O2 Activation and Alkane Oxidation by Copper Complexes With R‐dpa N3‐Tridentate Ligands: The Complex‐Based Dicopper Active Species as a Key Feature in the Efficient Alkane Oxidation

Chemistry – A European Journal, EarlyView.
Two reaction pathways, Paths 1 and 2, are involved in H2O2 activation by Cu complexes with N3‐tridentate ligands, depending on the ease of bridging structure formation. In Path 1, hydroxy radical (HO•) is formed from a hydroperoxo Cu(II) intermediate. In Path 2, a relevant complex‐based μ‐O• bridged Cu(II)2 active species is formed from a bis‐μ‐oxo Cu ...
Kyosuke Fujikawa, Momoe Kawahashi, Alexander Granichny, Siegfried Schindler, Hiroaki Kitagishi, Masahito Kodera   +5 more
wiley   +1 more source

Prevalence of lytic lesions in vertebrae.

, 2019
Prevalence of lytic lesions in vertebrae.
Thomas Reitmaier (2620993), Bernd Heinzle (6680948), Christine Cooper (3276291)   +2 more
core   +1 more source

Radiolabeled Coordination Polymer‐Loaded Microneedles for Synergistic Melanoma Brachytherapy–Immunotherapy via STING Activation and Pyroptosis

Exploration, EarlyView.
We developed a dissolvable microneedle patch that locally delivers a radiolabeled coordination polymer designed to simultaneously destroy tumor cells and stimulate antitumor immunity through STING activation and pyroptosis. This strategy significantly inhibited melanoma growth and improved the effectiveness of immune checkpoint therapy, highlighting a ...
Pian Yu, Shijun Xiang, Lu Hao, Jessica C. Hsu, Kaixuan Li, Rongxuan Yan, Ming Zhou, Yongxiang Tang, Ying Peng, Weibo Cai, Cong Peng, Peng Liu, Shuo Hu   +12 more
wiley   +1 more source

Phage lytic enzymes: a history

Virologica Sinica, 2015
There are many recent studies regarding the efficacy of bacteriophage-related lytic enzymes: the enzymes of 'bacteria-eaters' or viruses that infect bacteria. By degrading the cell wall of the targeted bacteria, these lytic enzymes have been shown to efficiently lyse Gram-positive bacteria without affecting normal flora and non-related bacteria. Recent
openaire   +3 more sources

Lytic potential of phage KO mutants.

, 2016
Lytic potential of phage KO mutants.
Chad W. Euler (401322), Douglas R. Deutsch (588547), Barbara Juncosa (845373), Patricia A. Ryan (401323), Vincent A. Fischetti (57436), W. Michael McShan (839517)   +5 more
core   +1 more source

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

Interdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang, Jiayi Yao, Xinxian Zhao, Yan Xu, Yifan Chen, Tianchi Chen, Ying Jian, Min Li   +7 more
wiley   +1 more source

Advanced Molecular Imaging Probes for Skeletal Diseases: Current Progress and Future Perspectives

iRADIOLOGY, EarlyView.
This review summarizes the potential molecular imaging techniques and probes for common orthopedic diseases, such as trauma, infection, metabolism, tumor, joint, spine and other fields, aiming to provide a basis for the development of a new generation of molecular imaging probes.
Shuo Guo, Yuling Cui, Zhiye Fan, Chenxin Jiang, Bowen Fu, Guangbin Cui, Yanli He   +6 more
wiley   +1 more source

Transcriptome analysis of Burkitt lymphoma cells treated with anti-convulsant drugs that are inhibitors of Epstein-Barr virus lytic reactivation.

PLoS ONE
Herpesviruses have two distinct life cycle stages, latency and lytic replication. Epstein-Barr virus (EBV), a gamma-herpesvirus, establishes latency in vivo and in cultured cells.
Kelly L Gorres, David M Reineke, George Miller   +2 more
doaj   +1 more source

Viral modulators of KSHV lytic replication

, 2009
Kaposi’s Sarcoma and the B-cell derived primary effusion lymphoma and multicentric Castleman’s Disease are all outcomes of infection with Kaposi’s Sarcoma– associated Herpesvirus (KSHV). A predominantly latent virus, KSHV also requires a subpopulation of
Gonzalez, Carlos M.
core   +1 more source

Binuclear Copper‐Dependent Oxidative Enzymes Involved in Fungal Natural Product Modifications

Journal of the Chinese Chemical Society, EarlyView.
This article summarizes recent biochemical characterizations of a new enzyme family named by the authors as binuclear copper‐dependent oxidative enzymes (BiNCOs). Found in fungal natural product biosynthesis, BiNCOs catalyze diverse CH functionalization reactions, including C(sp3)H halogenation, C(sp3)H hydroxylation, C(sp3)O macrocyclization, and ...
Chen‐Yu Chiang, Masao Ohashi, Yi Tang
wiley   +1 more source