The Predicted Lytic Transglycosylase HpaH from Xanthomonas campestris pv. vesicatoria Associates with the Type III Secretion System and Promotes Effector Protein Translocation. [PDF]
Hausner J+3 more
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Suppression of a deletion mutation in the gene encoding essential PBP2b reveals a new lytic transglycosylase involved in peripheral peptidoglycan synthesis in Streptococcus pneumoniae D39. [PDF]
Tsui HC+7 more
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The interplay between <i>Acinetobacter baumannii</i> ZigA and SltB promotes zinc homeostasis and cell envelope integrity. [PDF]
Critchlow JM+5 more
europepmc +1 more source
Phage Endolysins as Promising and Effective Candidates for Use Against Uropathogenic <i>Escherichia coli</i>. [PDF]
Wesołowski W+8 more
europepmc +1 more source
Deficiency in peptidoglycan recycling promotes β-lactam sensitivity in <i>Caulobacter crescentus</i>. [PDF]
Modi M+4 more
europepmc +1 more source
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Identification of Four Families of Peptidoglycan Lytic Transglycosylases
Journal of Molecular Evolution, 2001The lytic transglycosylases are a class of autolysins which cleave the bacterial cell wall heteropolymer peptidoglycan (murein) to facilitate its biosynthesis and turnover. A search of the National Center for Biotechnology Information (NCBI) databases using the primary sequences of the six characterized lytic transglycosylases of Escherichia coli, a ...
Anthony J. Clarke, Neil T. Blackburn
openaire +3 more sources
Assay for Lytic Transglycosylases: A Family of Peptidoglycan Lyases
Analytical Biochemistry, 2000An assay has been developed to monitor the activity of the lytic transglycosylases which does not involve the use of radiolabel. Samples of lytic transglycosylase were incubated with isolated and purified insoluble peptidoglycan as substrate for varying lengths of time.
Anthony J. Clarke, Neil T. Blackburn
openaire +3 more sources
‘Holy’ proteins II: the soluble lytic transglycosylase
Current Opinion in Structural Biology, 1994Enzymes involved in the metabolism of the bacterial cell wall peptidoglycan are excellent targets for antibiotics. Penicillins and related beta-lactam antibiotics inhibit the enzymes that act on the peptide cross-links of the peptidoglycan. The X-ray structure of the transglycosylase revealed a two-layered ring of alpha-helices in a right-handed ...
Bauke W. Dijkstra+1 more
openaire +3 more sources