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Characterization of the role of LtgB, a putative lytic transglycosylase in Neisseria gonorrhoeae
Microbiology, 2005Neisseria gonorrhoeaereleases monomeric peptidoglycan (PG) fragments during growth. These PG fragments affect pathogenesis-related phenotypes including induction of inflammatory cytokines and killing of ciliated fallopian tube cells. Although the biological activities of these molecules have been established in multiple systems, the genes and gene ...
Karen A. Cloud+4 more
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Subcellular Location of the Soluble Lytic Transglycosylase Homologue in Staphylococcus aureus
Current Microbiology, 2004The immunodominant antigen A, IsaA, of Staphylococcus aureus was found to include a putative soluble lytic transglycosylase domain in its C-terminal region. Since the presence of this distinctive domain suggested that the protein might participate in peptidoglycan turnover, as indicated in Gram-negative bacteria, its cellular location was investigated.
Shigemi Terakubo+2 more
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1996
Although cleaving the same glycosidic bond between MurNAc and GlcNAc in murein, lytic transglycosylases differ from lysozymes by catalyzing an intramolecular transglycosylation of the glycosyl-bond onto the C6 hydroxyl group of the muramic acid residue yielding 1.6-anhydromuramic acid-carrying products.
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Although cleaving the same glycosidic bond between MurNAc and GlcNAc in murein, lytic transglycosylases differ from lysozymes by catalyzing an intramolecular transglycosylation of the glycosyl-bond onto the C6 hydroxyl group of the muramic acid residue yielding 1.6-anhydromuramic acid-carrying products.
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INHIBITION OF PSEUDOMONAS AERUGINOSA LYTIC TRANSGLYCOSYLASES BY NAG-THIAZOLINE
XXIst International Carbohydrate Symposium 2002, 2002Christopher W. Reid+2 more
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Structure and function of lytic transglycosylases from Pseudomonas aeruginosa
2010Tuula T. Teeri+5 more
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