Results 41 to 50 of about 40,509 (150)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
De nouveaux métiers, à la charnière entre accompagnement des personnes, médiation et répression, ont émergé depuis une vingtaine d’années. Ces nouveaux métiers contribuent à rendre plus floue la frontière entre police et contrôle social.
Jacques de Maillard
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Au cœur de la Recherche du temps perdu se trouve une réflexion sur les nouvelles technologies téléphoniques qui révolutionnent la phénoménologie de l’écoute et de la communication au début du XXe siècle. L’expérience de la parole à distance, le relais ou
Jesse Dylan McCarthy
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Médiations translangagières du texte littéraire en classe de langue
Cet article se propose d’aborder la médiation du texte littéraire à partir d’une approche translangagière mise en œuvre dans un dispositif universitaire plurilingue et pluriculturel d’apprentissage du français comme langue étrangère de niveau avancé ...
Nathalie Borgé
doaj +1 more source
Compétences numériques et nouvelle loi éducative espagnole (LOMLOE) : pour la médiation et le sous-titrage en cours de français [PDF]
En Espagne, une nouvelle loi éducative ayant pour objectif d’adapter le système éducatif aux défis du XXIe siècle a été approuvée et mise en place dans les établissements scolaires de l’enseignement primaire et secondaire en septembre 2022.
Sara Estévez Aubry
doaj
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source

