Results 61 to 70 of about 85,736 (178)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

L’atelier d’écriture théâtrale comme pratique de médiation entre création littéraire et phénomène social : quand le fait littéraire émerge du fait social

open access: yesRelief: Revue Électronique de Littérature Francaise, 2020
L’atelier d’écriture théâtrale peut être appréhendé en tant que pratique de médiation littéraire et artistique dans la mesure où il peut permettre à des individus de s’ouvrir à des objets culturels qu’ils ne fréquentent pas habituellement.
Laurianne Perzo
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Médiation et formation à la médiation scientifique (MeFo): Programme SAPS-CSTI (AAPG2020/ Edition 2022)

open access: yes
This project is in the continuity of the winning projects of the 2018-2019 AAP because the University of Tours chooses to pursue its strategy of regional structuring and strengthening of CSTI through the production of mediation capsules and the ...
Fresquet, Nadine
core   +4 more sources

Structures de médiation et intégration des immigrants haïtiens à Paris

open access: yesRevue Européenne des Migrations Internationales, 2008
Mediating Structures and the Adaptation of Haitian Immigrants in Paris. In this article, I use official French government data and interviews with Haitian immigrants to analyze the paths through which Haitians have entered and settled in France.
Margarita Mooney
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Médiation [PDF]

open access: yes, 2020
| BABYLONIA tema 3|20206Tema Lorsque nous avons commencé à concep- tualiser ce numéro spécial de Babylonia, nous ne nous attendions pas à ce que son titre – médiation – ne soit si adapté et si actuel. L’idée même de médiation prend en effet un sens
Losa, Stefano, Lambelet, Amelia
core  

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