Sex assignment in conditions affecting sex development [PDF]
The newborn infant with atypical genitalia presents a challenging clinical scenario and requires expert input. There have been appreciable advances in our knowledge of the underlying causes that may lead to a mere difference or a more serious disorder of
Ahmed, S. Faisal, Markosyan, Renata
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Müllerian inhibiting substance/anti-Müllerian hormone: A novel treatment for gynecologic tumors [PDF]
Müllerian inhibiting substance (MIS), also called anti-Müllerian hormone (AMH), is a member of the transforming growth factor-β super-family of growth and differentiation response modifiers.
Donahoe, Patricia K. +2 more
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Persistent mullerian duct syndrome
Persistent Mullerian duct syndrome (PMDS) is a rare form of internal male pseudohermaphroditism in which Mullerian duct derivatives are seen in a male patient. This syndrome is characterized by the persistence of Mullerian duct derivatives (i.e.
Divya Renu, B Ganesh Rao, K Ranganath
doaj +3 more sources
Vertebral defect, anal atresia, cardiac defect, tracheoesophageal fistula/esophageal atresia, renal defect, and limb defect association with Mayer-Rokitansky-Küster-Hauser syndrome in co-occurrence:two case reports and a review of the literature [PDF]
Background: The vertebral defect, anal atresia, cardiac defect, tracheoesophageal fistula/esophageal atresia, renal defect, and limb defect association and Mayer-Rokitansky-Küster-Hauser syndrome are rare conditions.
Bjørsum-Meyer, T. +3 more
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Transcriptional landscape of the embryonic chicken Müllerian duct
Background Müllerian ducts are paired embryonic tubes that give rise to the female reproductive tract in vertebrates. Many disorders of female reproduction can be attributed to anomalies of Müllerian duct development.
Zahida Yesmin Roly +5 more
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The DNA methylome of cervical cells can predict the presence of ovarian cancer
Most ovarian cancers originate from cells originally derived from Müllerian Duct cells. Here, the authors show that the methylation profile of Müllerian Duct cells isolated from cervical samples can predict whether a woman has cervical cancer.
James E. Barrett +12 more
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Persistent Mullerian Duct Syndrome with Malignant Conversion of Mullerian Remnant
A case report of a very rare entity of persistent Müllerian duct syndrome with malignant transformation of Mullerian remnant is presented. A twenty-two-year-old phenotypically normal male presented with complain of hematuria and lower abdominal pain.
Abhilasha Jain +3 more
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Regulation of ovarian function: the role of anti-Mullerian hormone [PDF]
Anti-Mullerian hormone (AMH), also known as Mullerian inhibiting substance, is a member of the transforming growth factor beta superfamily of growth and differentiation factors.
Durlinger, A.L.L. (Alexandra) +2 more
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Dicer is required for female reproductive tract development and fertility in the mouse. [PDF]
Dicer encodes a riboendonuclease required for microRNA biosynthesis. Dicer was inactivated in Müllerian duct mesenchyme-derived tissues of the reproductive tract of the mouse, using an Amhr2-Cre allele.
Alvarez-Garcia +45 more
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"Sexual differentiation: From genes to gender" [PDF]
Amy Wisniewski is Assistant Professor of Biology at Drake University, Des Moines, Iowa. She can be contacted at amy.wisniewski@drake.eduA person's sex can be considered across various levels.
Migeon, Claude J., Wisniewski, Amy B.
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