Results 41 to 50 of about 114,600 (162)

Persistent Mullerian Duct Syndrome with Seminoma of Cryptorchid Testis: A Rare Case of Testicular Torsion Complication

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Persistent Mullerian duct syndrome (PDMS) is characterized by the presence of Mullerian duct derivatives in a phenotypically and genetically normal individual. This is a case of a male in his 40s who was being evaluated for infertility.
Sikander Purohit, Anuradha C. K. Rao, Mary Mathew, Brij M. K. Singh   +3 more
doaj   +1 more source

Histological Characterization and Comparative Transcriptomic Analysis of Gonads During Early Sex Differentiation in the Northern Snakehead (Channa argus)

Animal Research and One Health, EarlyView.
This study delineates the early sex differentiation timeline in the northern snakehead (Channa argus). These findings provide a foundation for future sex‐control breeding in this economically important species. ABSTRACT The northern snakehead (Channa argus) is an economically important aquaculture species in China.
Chaonan Sun, Donglei Sun, Haishen Wen, Xin Qi, Chao Li, Xiaoyan Zhang, Yun Li   +6 more
wiley   +1 more source

Persistent Mullerian Duct Syndrome with Ovarian Endometriosis-A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2016
Persistent Mullerian Duct Syndrome (PMDS) is a rare form of internal male pseudohermaphroditism, characterised by presence of Mullerian duct derivatives in a genotypic and phenotypic male.
Savitri Mallikarjun Nerune, Surekha B. Hippargi, Namrata B.Mestri, Nikhil M.Mehrotra   +3 more
doaj   +1 more source

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

Animal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

SMAD2/3 signaling regulates initiation of mouse Wolffian ducts and proximal differentiation in Müllerian ducts

FEBS Open Bio
Male and female reproductive tracts develop from anterior intermediate mesoderm with similar differentiation processes. The anterior intermediate mesoderm develops into the mesonephros, and the Wolffian duct initiates by epithelialization in the ...
Tadaaki Nakajima, Akihiro Imai, Chihiro Ishii, Kota Tsuruyama, Risa Yamanaka, Yasuhiro Tomooka, Shinta Saito, Noritaka Adachi, Satomi Kohno, Tomomi Sato   +9 more
doaj   +1 more source

Complex mullerian duct anomaly in a young female with primary amenorrhoea, infertility, and chronic pelvic pain

Journal of Human Reproductive Sciences, 2012
Mullerian duct anomalies, though rare, can be a treatable cause of pelvic pain and infertility. Various complex Mullerian duct anomalies may exist with combination of features of more than one class.
Sanyal Kumar, Bhawna Satija, Leena Wadhwa   +2 more
doaj   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Insensibilidade androgênica completa e hérnia inguinal: relato de 3 casos. [PDF]

, 1999
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Pediatria, Curso de Medicina, Florianópolis ...
Queirós, Raquel Campos Galvão de
core  

DMRT1 is required for Müllerian duct formation in the chicken embryo [PDF]

, 2015
DMRT1 is a conserved transcription factor with a central role in gonadal sex differentiation. In all vertebrates studied, DMRT1 plays an essential function in testis development and/or maintenance.
Ayers, K.L., Roeszler, K.N., Cutting, A.D., Smith, C.A., Sinclair, A.H.   +4 more
core   +1 more source

Studying Müllerian duct anomalies - from cataloguing phenotypes to discovering causation [PDF]

, 2021
Müllerian duct anomalies (MDAs) are developmental disorders of the Müllerian duct, the embryonic anlage of most of the female reproductive tract. The prevalence of MDAs is 6.7% in the general female population and 16.7% in women who exhibit recurrent ...
Santana González, Laura, Mara Artibani, Ahmed Ashour Ahmed, Laura Santana González, Artibani, Mara, Ahmed, Ahmed Ashour   +5 more
core   +1 more source